Asian equities traded in the US as American depositary receipts fell Wednesday morning with the S&P Asia 50 ADR Index declining 0.6% to 2,049.37

From North Asia, the gainers were led by computer hardware maker Canaan (CAN) and ad agency iClick Interactive Asia Group (ICLK), which rose 4.5% and 3.8% respectively. They were followed by automotive e-commerce platform Cango (CANG) and brand platform 36Kr (KRKR), which were up 3.7% and 3.1% respectively.

The decliners from North Asia were led by property technology company Fangdd Network Group (DUO) and education company 17 Education & Technology Group (YQ), which fell 11% and 6.8% respectively. They were followed by e-commerce fashion platform MOGU (MOGU) and used car e-commerce platform Uxin (UXIN), which dropped 5.6% each.

From South Asia, the gainers were led by tech conglomerate Sea (SE) and pharmaceutical company Dr. Reddy's Laboratories (RDY), which rose 1.1% and 0.8% respectively. They were followed by IT firm Wipro (WIT) and financial services company HDFC Bank (HDB), which were up 0.5% and 0.3% respectively.

The decliners from South Asia were led by telecommunications operators PLDT (PHI) and Telekomunikasi Indonesia (TLK), which lost 1.6% and 0.6% respectively. They were followed by business process management company WNS (WNS) and IT firm Infosys (INFY), which were down 0.2% and 0.1% respectively.