BRIEF-Karyopharm Announces Favorable Change In Co-Primary Endpoint For Pivotal Phase 3 SENTRY Trial In Myelofibrosis

Reuters

2024-10-31

Oct 31 (Reuters) - Karyopharm Therapeutics Inc :

* KARYOPHARM ANNOUNCES FAVORABLE CHANGE IN CO-PRIMARY ENDPOINT FOR PIVOTAL PHASE 3 SENTRY TRIAL IN MYELOFIBROSIS

* KARYOPHARM THERAPEUTICS INC - CO-PRIMARY ENDPOINT CHANGED TO ABSOLUTE TOTAL SYMPTOM SCORE (ABS-TSS)

* KARYOPHARM THERAPEUTICS INC - SPLEEN VOLUME RESPONSE RATE ≥ 35% (SVR35) REMAINS CO-PRIMARY ENDPOINT

* KARYOPHARM THERAPEUTICS INC - SENTRY TRIAL SAMPLE SIZE INCREASED TO APPROXIMATELY 350 PATIENTS

Source text: Further company coverage:

((Reuters.Briefs@thomsonreuters.com;))

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