Voyager Therapeutics (VYGR) said Wednesday it selected its lead development candidate for tau silencing gene therapy program in Alzheimer's disease and expects to file regulatory applications for the candidate in the US and Canada in 2026.
The company said that the candidate, VY1706, showed reductions in levels of tau - the protein that contributes Alzheimer's if accumulated abnormally - by 50% to 73% across the brain in a non-human primate study.
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