European equities traded in the US as American depositary receipts were slightly lower late Wednesday morning, declining 0.14% to 1,346.88 on the S&P Europe Select ADR Index.

From continental Europe, the gainers were led by semiconductor company Sequans Communications (SQNS) and biopharmaceutical firm DBV Technologies (DBVT), which rose 3.3% and 2.1%, respectively. They were followed by software firm SAP (SAP) and internet advertising company Criteo (CRTO), which were up 1.8% and 1.6%, respectively.

The decliners from continental Europe were led by furniture maker Natuzzi (NTZ) and pharmaceutical company Ascendis Pharma (ASND), which fell 6.4% and 5.7% respectively. They were followed by biotech firm Evaxion Biotech (EVAX) and biopharmaceutical company Genfit (GNFT), which lost 4% and 3.7% respectively.

From the UK and Ireland, the gainers were led by biopharmaceutical companies Biodexa Pharmaceuticals (BDRX) and Adaptimmune Therapeutics (ADAP), which increased 3.3% and 0.9% respectively. They were followed by biopharmaceutical company NuCana (NCNA) and hospitality company InterContinental Hotels Group (IHG), which were up 0.8% and 0.7% respectively.

The decliners from the UK and Ireland were led by biopharmaceutical companies Bicycle Therapeutics (BCYC) and Akari Therapeutics (AKTX), which dropped 6.4% and 3.5% respectively. They were followed by biopharmaceutical company Mereo BioPharma Group (MREO) and utilities company National Grid (NGG), which were down 2.3% and 2.1% respectively.