Innate Pharma SA (IPHA) said Monday it has dosed its first patient in a phase 1 study to investigate the safety and tolerability of IPH4502, an antibody-drug conjugate for the potential treatment of patients with advanced solid tumors known to express Nectin-4.
IPH4502 is designed to target Nectin-4, a cell adhesion molecule in several types of solid tumors, including urothelial carcinoma, breast cancer, non-small cell lung cancer, and gastrointestinal cancer, the company said.
The study plans to enroll about 105 patients, the company said.
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