** Industrial and aerospace co Honeywell International HON.O down ~5.5% at $210.53 in afternoon trading

** Expects 2025 adjusted profit between $10.10 and $10.50 per share, below analysts' average estimate of $10.93, according to data compiled by LSEG.

** 2025 sales outlook of between $39.6 bln and $40.6 bln also falls short of analysts' expectations of $41.22 bln

** Co says on Thursday it will separate its aerospace and automation businesses into separate entities, alongside its previously announced spin-off of the advanced materials unit

** Some experts suggest gains from the separation will take time to materialize

** HON has been grappling with sluggish demand in its industrial automation segment as a pandemic-driven boom in e-commerce moderates

** 13 of 27 brokerages rate the stock "buy" or "higher", 14 "hold"; with a median PT of $240, according to data compiled by LSEG

** Including session's move, shares down ~6.7% YTD after rising 7.7% in 2024

(Reporting by Rupali Chaudhary in Bengaluru)

((Rupali.Chaudhary@thomsonreuters.com))