Health care stocks were mixed premarket Tuesday, with The Health Care Select Sector SPDR Fund (XLV) marginally higher and the iShares Biotechnology ETF (IBB) down 0.6%.

Illumina (ILMN) is now prohibited from exporting gene sequencers to China as the company was added to the country's "Unreliable Entity List," according to a statement from China's Ministry of Commerce. Illumina shares were down more than 4% pre-bell.

Wave Life Sciences (WVE) stock was nearly 4% higher after the company reported that it swung to Q4 net income as revenue rose during the period.

BeiGene (ONC) shares were up over 2% after the company said the US Food and Drug Administration approved Tevimbra, in combination with platinum-containing chemotherapy, for the first-line treatment of certain adults with unresectable or metastatic esophageal squamous cell carcinoma.