【辉瑞公布博瑞纳®CROWN研究亚洲亚组结果，63%ALK阳性晚期非小细胞肺癌患者五年后仍未发生疾病进展】金十数据9月15日讯，辉瑞公司在2024年欧洲肿瘤内科学会（ESMO）期间公布了第三代ALK抑制剂博瑞纳®（洛拉替尼）CROWN Ⅲ期研究亚洲亚组的最新数据。数据显示，63%的患者在5年后仍未发生疾病进展或死亡, 洛拉替尼可改善患者的客观缓解率（ORR）和颅内缓解率（IC ORR）。5年随访数据显示，洛拉替尼在亚洲亚组中的有效性与安全性与CROWN研究整体人群结果一致，为ALK阳性NSCLC患者带来前所未有的获益。为洛拉替尼在一线的应用提供了证据支持。
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