金吾财讯 | Sage Therapeutics(SAGE)盘初一度跌超12%，截至发稿，涨0.89%，报6.78美元。消息面上，Sage Therapeutics周二宣布阿尔茨海默病治疗药物dalzanemdor(SAGE-718)的中期试验未能达到主要终点后，盘前一度下跌超30%，截至发稿，该股下跌11%。该公司援引第二阶段LIGHTWAVE试验的数据说，根据该研究主要目标临床规模来衡量，dalzanemdor在疾病影响方面与基线相比并没有统计学上的显著差异。考虑到试验的结果，这家总部位于马萨诸塞州剑桥的生物技术公司表示，将不再开发用于阿尔茨海默病的dalzanemdor。然而，该公司补充说，没有出现新的安全信号，而且研究药物在患者中耐受性良好。
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