国泰君安研报指出,诺诚健华(9969.HK)Tyk2(ICP-488)治疗中重度斑块状银屑病二期临床数据优异。ICP-488国内进度领先,展示出不输同类竞品潜力,血液瘤管线进展顺利,慢病管线加速推进。公司创新管线推进顺利,拓展自免和实体瘤治疗。①Tafasitamab中国r/rDLBCL 的BLA已受理,预计25年获批。②预计ICP332(TYK2-JH1)在2024Q4开启AD的III期以及开启白癜风II/III期;美国首例患者已给药。③ICP-723 (NTRK)的晚期实体瘤注册临床试验加速推进,预计2025Q1递交NDA。⑤ICP-189联合伏美替尼仍在进展中,预计2024年底取得 PoC。
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