The most-talked-about stocks in the Reddit subforum Wallstreetbets were mostly lower hours before Wednesday's opening bell.

Enphase Energy (ENPH) fell by 15.1% in pre-bell hours, reversing a 2% increase from the previous session. Enphase Energy reported Q3 non-GAAP earnings of $0.65 per diluted share, down from $1.02 a year earlier.

McDonald's (MCD) declined by 7% in premarket activity, following a 0.1% fall from the previous session. The US Centers for Disease Control and Prevention said an E. coli outbreak in 10 states is linked to the company's Quarter Pounder burgers.

Oklo (OKLO) was 3.2% lower pre-bell, extending losses after closing Tuesday with a 6.6% fall.

Nvidia (NVDA) was 0.7% lower in premarket hours, following a 0.1% decline from the previous session.

Tesla (TSLA) declined by 0.6% premarket, following a 0.4% fall at Tuesday's close.

Advanced Micro Devices (AMD) fell by 0.5% hours before market open, after closing Tuesday with a 2.4% decline.

Microsoft (MSFT) was down 0.1% in pre-bell hours, swinging from a 2.1% increase from the previous session.

Bucking the trend, Trump Media & Technology (DJT) rose by 5.7% in premarket activity, following a 9.9% increase at Tuesday's close. Trump Media & Technology said it released an app for Android TVs to access its Truth+ streaming platform.

Price: 78.45, Change: -13.78, Percent Change: -14.94