安进首创C5aR拮抗剂“阿伐可泮”于中国获批上市

智通财经
05 Nov 2024

智通财经APP获悉,11月5日,国家药品监督管理局(NMPA)官网显示,安进(AMGN.US)和CSL Vifor共同开发的阿伐可泮胶囊(avacopan)的上市申请已获得批准,推测用于治疗抗中性粒细胞胞质抗体(ANCA)相关血管炎(AAV)。据悉,阿伐可泮是一种补体5a受体(C5aR)拮抗剂,可抑制C5aR和过敏毒素C5a之间的相互作用。阿伐可泮阻断C5a介导的中性粒细胞激活和迁移。该药于...

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