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11月5日 - ** 生物技术公司Beam Therapeutics 股价下跌3.30%,至23.56美元
** 摘要显示,在该公司基于CRISPR技术的细胞疗法BEAM-101的早中期试验中,一名镰状细胞病患者因呼吸衰竭死亡。 (link)
** 呼吸衰竭很可能与一种名为 "busulfan "的化疗调理有关,这种化疗用于为患者输液做准备。
** 死亡发生在输注后四个月
** 公司称已有八名患者接受了 BEAM-101 治疗
** 虽然病人的死亡是不幸的,但我们认为这一事件凸显了对毒性较低的预处理方案的需求。
** Vertex 和CRISPR Therapeutics的 Casgevy和蓝鸟生物的 Lyfgenia被批准用于治疗镰状细胞病,这是一组遗传性血液疾病。
** BEAM 第三季度净亏损为 9,670 万美元,合每股亏损 1.17 美元,去年同期净亏损为 9,610 万美元,合每股亏损 1.22 美元。
** BEAM 股价今年以来下跌了约 15
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