Is This a New Reason to Buy Pfizer Stock Hand Over Fist?

Motley Fool
29 Nov 2024
  • Pfizer is forging ahead with a new collaboration for developing obesity drugs.
  • It's working with a biotech that has a very ambitious drug development platform.
  • It'll be a while before investors find out if the platform is too ambitious or just right.

Despite Pfizer's (PFE 0.23%) recent struggles with falling earnings and a bid by an activist investor to unseat its leadership, the pharma juggernaut is still actively advancing its core priorities and giving investors plenty of reasons to consider buying its stock while it's cheap.

With that in mind, here's one new initiative that's worth thinking about if you're wondering about whether to make an investment.

This new play could lead to super-effective medicines down the line

On Nov. 20, Pfizer announced that its strategic partnership with Flagship Pioneering, a highly prestigious biopharma venture capital (VC) group, had agreed on a new collaboration.

Per the agreement, one of Flagship's portfolio companies, a private biotech called Ampersand Biomedicines, will work with Pfizer to potentially develop new medicines for obesity. Given that the market for weight loss drugs could be as large as $100 billion by 2030, there's little doubt that there's great potential for these businesses as they work together.

Ampersand's technology platform aims to streamline the development of multi-component drugs that can localize themselves precisely to the appropriate physiological locations in the patient's body, perhaps including targeted locations inside specific types of cells, and then deliver a high-impact payload for the intended medicinal effect.

Unlike technologies that are conceptually similar in terms of their goals, such as antibody-drug conjugates (ADCs), Ampersand's technology can supposedly be implemented across a wide range of different therapeutic formats and drug delivery systems, utilizing everything from small molecules to biologics and even nucleic acids like mRNA.

In plain English, this means that the biotech could develop novel approaches to treating obesity and that those novel approaches might end up being significantly more effective than the drugs that are currently on the market or in development elsewhere.

But that's an ambitious goal. This is not to suggest that its highly flexible multiformat approach is impossible, but in practice it'll need to tackle a bunch of engineering issues beyond what would normally be expected. It would need to carefully calibrate the physical and chemical interactions between each drug format and each delivery system from scratch -- and doing it correctly even for one combination is a very complicated and challenging process.

Wait to see concrete results

Even so, don't get too bearish on the Ampersand-Pfizer collaboration. The pair will have plenty of resources to work with, as well as access to a lot of the best intellectual property (IP) and the talent for developing many of the somewhat disparate biotechnologies in its repertoire. Likewise, the two businesses have a massive trove of biological data to work with, which will certainly improve their odds of success.

At the same time, there is no reason to rush to buy Pfizer's stock on the basis of this new collaboration. There's no guarantee that Ampersand's approach will lead to any new medicines within the next five years or so, even with the help of Pfizer's formidable research and development (R&D) resources and expert guidance. Presently, there's no indication that the pair will be launching any new clinical trials anytime soon.

This collaboration is just getting started, and it will likely entail quite a lot of laboratory work as well as extensive pre-clinical testing that probably hasn't even been envisioned as of yet. Even if they did somehow start actual clinical trials relatively soon, trials can fail or take years to conclude in entirety, so the prospects of anyone making money quickly on the basis of this collaboration are effectively zero.

That means if Pfizer ever does commercialize a drug stemming from this collaboration, it'll be a very laggardly latecomer to the market for anti-obesity medicines. Thus, it would need to produce a very powerful and/or highly tolerable new medicine if it wanted to secure a significant market share. So, keep an eye out for announcements about any new obesity medicines in the works. Until then, there's not much reason to update your investment thesis on Pfizer.

Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.

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