Relmada Therapeutics Study of Major Depressive Disorder Treatment Assessed as Futile

Dow Jones

04 Dec 2024

By Denny Jacob

Relmada Therapeutics said an interim analysis of a study assessing a treatment for major depressive disorder is futile and unlikely to meet the primary efficacy endpoint with statistical significance.

The late-stage biotechnology company said an interim analysis of Reliance II conducted by the Independent Data Monitoring Committee determined its assessment of the Phase 3 study. Reliance II was designed to evaluate REL-1017 as an adjunctive treatment for major depressive disorder to be used in combination with other approved anti-depressants.

Relmada said no new safety signals were reported.

"Based on these results, Relmada will evaluate the full dataset to determine next steps for the REL-1017 program," said Chief Executive Sergio Traversa. He added that Relmada will continue to advance a Phase 1 study of REL-P11 as a treatment of metabolic disease.

Trading was halted at 7:25 a.m. ET ahead of its disclosure and has yet to resume trading as of 7:47 a.m. ET.

Write to Denny Jacob at denny.jacob@wsj.com

(END) Dow Jones Newswires

December 04, 2024 07:50 ET (12:50 GMT)

Copyright (c) 2024 Dow Jones & Company, Inc.

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Reliance II was designed to evaluate REL-1017 as an adjunctive treatment for major depressive disorder to be used in combination with other approved anti-depressants. \n</p>\n<p>\n  Relmada said no new safety signals were reported. \n</p>\n<p>\n  \"Based on these results, Relmada will evaluate the full dataset to determine next steps for the REL-1017 program,\" said Chief Executive Sergio Traversa. 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Reliance II was designed to evaluate REL-1017 as an adjunctive treatment for major depressive disorder to be used in combination with other approved anti-depressants.Relmada said no new safety signals were reported.\"Based on these results, Relmada will evaluate the full dataset to determine next steps for the REL-1017 program,\" said Chief Executive Sergio Traversa. He added that Relmada will continue to advance a Phase 1 study of REL-P11 as a treatment of metabolic disease.Trading was halted at 7:25 a.m. ET ahead of its disclosure and has yet to resume trading as of 7:47 a.m. ET.","collect":0,"end_time":0,"defaultTopTitle":"","property":[],"viewcount":null,"language":"en","relate_stocks":{"BK4139":"生物科技","BK4007":"制药","RLMD":"Relmada Therapeutics, Inc.","LENZ":"Therapeutics"},"translate_title":"Relmada Therapeutics重度抑郁症治疗研究被评估为无效","themeId":null,"isJumpTheme":false,"ttsUrl":null,"symbols_score_info":{"LENZ":1,"RLMD":0.9},"content_text":"By Denny Jacob \n\n\n \n\n\n  Relmada Therapeutics said an interim analysis of a study assessing a treatment for major depressive disorder is futile and unlikely to meet the primary efficacy endpoint with statistical significance. \n\n\n  The late-stage biotechnology company said an interim analysis of Reliance II conducted by the Independent Data Monitoring Committee determined its assessment of the Phase 3 study. 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