智通财经APP获悉，科伦博泰生物-B(06990)涨超5%，截至发稿，涨5.27%，报193.5港元，成交额5210.24万港元。
天风证券发布研报称，科伦博泰拥有自主知识产权的ADC研发平台OptiDC，具备从研发到生产的全流程开发体系。截至2024年6月，公司共有5款ADC处于临床开发阶段，其中A166(HER2-ADC)和SKB264 (TROP2-ADC)已经进入NDA阶段，SKB315 (Claudin18.2-ADC)、SKB410(Nectin-4)和SKB518(PTK7)处于临床Ⅰ期阶段，多款产品处于临床前研究阶段。公司的ADC研发能力深受国际巨头默沙东认可，就SKB264以及其他在研品种达成多项合作，共计合作款项约118亿美元。
该行续指，公司目前有四款药物的NDA申请已获CDE受理，分别是A167(PD-L1单抗)、A166(HER2 ADC)、A140(西妥昔单抗生物类似药)和SKB264(TROP2ADC)。后续管线已形成梯队，A223 (JAK1/2抑制剂)、A400 (RET抑制剂)等管线已进入II期临床;SKB410(Nectin4 ADC)、SKB378(TSLP单抗)和SKB518(PTK7)等管线处于I期临床试验阶段。
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