港股异动 | 基石药业-B(02616)涨近7% 三抗新药已在澳大利亚递交临床试验申请

智通财经
02 Jan

智通财经APP获悉,基石药业-B(02616)涨近7%,截至发稿,涨6.96%,报2.46港元,成交额1192.43万港元。

消息面上,基石药业此前宣布,公司用于治疗多种实体瘤的管线2.0重磅产品CS2009(PD-1/VEGF/CTLA-4三特异性抗体)已在澳大利亚递交临床试验申请。该研究也已于Clinicaltrials.gov网站登记(登记号:NCT06741644)并公示。临床前数据显示,CS2009具有明显优于潜在竞品的抗肿瘤活性,有望覆盖广泛瘤种、包括非小细胞肺癌,卵巢癌,肾细胞癌,宫颈癌,肝癌,胃癌等,成为同类首创/同类最优的下一代肿瘤免疫骨架产品。

另外,公司管线2.0重磅产品CS5001(ROR1 ADC)全球多中心1b期临床试验顺利完成首例患者入组。临床数据显示,CS5001作为单药治疗侵袭性和惰性晚期淋巴瘤的客观缓解率(ORR)高于同类竞品,具有快速上市注册及冲击一线联合治疗格局的潜力。据悉,CS5001全球多中心试验在美国、澳大利亚和中国同步进行,目前已推进至1b期进行剂量优化,后续潜在扩展为II期单臂注册研究。

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