智通财经APP获悉,科济药业-B(02171)早盘涨近5%,截至发稿,涨3.84%,报9.46港元,成交额1885.51万港元。
消息面上,科济药业宣布,公司自主研发、针对CD19/CD20双标靶的通用型CAR-T细胞治疗候选产品KJ-C2219,已在中国启动一项针对复发陂难治性B细胞非何杰金氏淋巴瘤研究者发起的临床试验。KJ-C2219基于THANK-u Plus平台开发,计划用于治疗血液恶性肿瘤和自体免疫疾病。
此外,科济药业公布,关键II期临床试验CT041-ST-01(NCT04581473)已取得阳性结果。该试验是一项在中国进行的随机对照、多中心的临床试验,旨在评估舒瑞基奥仑赛注射液(研发代码:CT041,一种靶向Claudin18.2自体 CAR-T细胞候选产品)治疗Claudin18.2表达阳性、既往接受过至少2线治疗失败的晚期胃╱食管胃结合部腺癌的有效性和安全性,受试者以2:1的比例随机分配至舒瑞基奥仑赛注射液组或研究者选择治疗组(包括紫杉醇、多西他赛、伊立替康、阿帕替尼或纳武利尤单抗)。
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