Silexion Shares Rise Late Following Pretrial Data From Pancreatic Cancer Treatment Showing Efficacy

MT Newswires Live

Jan 16, 2025

Silexion Therapeutics (SLXN) was 74% higher in Wednesday's after-hours session, after it disclosed preclinical data demonstrated the synergistic efficacy of its SIL-204 candidate to treat certain form of pancreatic cancer.

The data show that SIL-204 worked well in combination with the primary components of two chemotherapies, 5-fluorouracil and irinotecan, in human cell lines containing pancreatic cancer with KRAS G12D mutations, the most common form of the disease. SIL-204 also showed synergistic activity with gemcitabine, another chemotherapeutic agent, Silexion said.

The company currently is preparing SIL-204 for upcoming clinical trials, with toxicology studies set to begin within a few months and phase 2/3 testing planned for H1 2026, beginning with locally advanced pancreatic cancer.

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SIL-204 also showed synergistic activity with gemcitabine, another chemotherapeutic agent, Silexion said.</p><p>The company currently is preparing SIL-204 for upcoming clinical trials, with toxicology studies set to begin within a few months and phase 2/3 testing planned for H1 2026, beginning with locally advanced pancreatic cancer.</p></body></html>\n\n</article>\n</div>\n</body>\n</html>\n","isBrief":false,"type":0,"news_type":1,"symbol":"BK4139","symbol_name":"生物科技","start_time":0,"source_url":"https://www.mtnewswires.com/","article_id":"2503603791","we_media_id":"1092851196","thumbnails":[],"rights":null,"url":"https://stock-news.laohu8.com/highlight/detail?id=2503603791","pubTimestamp":1736979797,"columns":[],"sourceInfo":{"source_id":"mtnewswires_news","name":"MT Newswires"},"weMediaInfo":{"media_name":"MT Newswires Live","introduction":"The most recognized names in North America, Europe and Asia rely on MT Newswires to power their applications. 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