智通财经APP获悉,绿叶制药(02186)涨近5%,截至发稿,涨4.98%,报2.11港元,成交额3177.41万港元。
消息面上,近日,绿叶制药发布公告,集团自主开发的新一代抗精神病药物LY03020已获得美国食品药品监督管理局许可开展临床试验,拟用于治疗精神分裂症。LY03020基于集团新分子实体╱新治疗实体技术平台开发,是全球首个痕量胺相关受体1和5-羟色胺2C受体双靶点激动剂。LY03020亦在中国进入临床阶段。
据介绍,面对广泛未被满足的临床需求,新一代抗精神分裂症药物被寄予厚望:不同于已上市抗精神分裂症药物抑制突触后膜D2和5-HT2A受体的机制,该类药物主要以激动突触前膜为特征,有望减少锥体外系反应和代谢综合征等不良反应,显著改善精神分裂症阳性、阴性症状和认知症状等。
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