港股异动 | 乐普生物-B(02157)涨超10% 临床前ADC新药MRG007授权ArriVent 总交易额高达12亿美元

智通财经
23 Jan

智通财经APP获悉,乐普生物-B(02157)涨超10%,截至发稿,涨9.58%,报2.63港元,成交额2845.82万港元。

消息面上,乐普生物昨日宣布,与ArriVent BioPharma, Inc.就针对消化道癌的潜在同类最佳抗体偶联药物MRG007达成全球独家许可协议。根据协议,乐普生物授予ArriVent在大中华区(包括中国大陆、中国香港、中国澳门和中国台湾)以外地区开发、制造和商业化MRG007的全球独家许可。乐普生物将获得总计4700万美元的一次性首付款和近期里程碑付款,和最高达11.6亿美元的开发、注册和销售等里程碑付款,以及基于大中华区以外地区净销售额的分级特许权使用费。

据悉,MRG007在消化道癌的临床前模型中表现出强大的抗肿瘤活性,在IND支持性研究中显示出较高的治疗指数。首个IND申请计划于2025年上半年提交,初步临床开发重点是结直肠癌、胰腺癌及其他消化道恶性肿瘤。

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