百时美施贵宝(Bristol Myers Squibb)公司周一宣布,评估Breyanzi药物用于治疗复发难治性惰性B细胞非霍奇金淋巴瘤成人患者的 TRANSCEND FL二期试验在边缘区淋巴瘤队列研究中达到了主要终点。
该2期试验显示了具有统计学和临床意义的总体缓解率(ORR)。它还达到了完全缓解率(CRR)的关键次要终点,未观察到新的安全性信号。
百时美施贵宝公司指出:“凭借这些数据,Breyanzi证明了其针对第五种癌症类型的疗效和可控的安全性,这是所有针对CD19的CAR-T细胞疗法中数据最高的。”
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