VHL综合征VonHippel-Lindau(VHL)综合征是一种罕见的遗传病,是VHL抑癌基因突变引起的一种常染色体显性遗传,全球约有20万人患病。VHL基因定位于3p25-3p26,全长10kb,编码VHL蛋白(pVHL)。pVHL由α和β结构域构成,主要通过α结构域与延长因子C结合,进而与延长因子B、Cullin蛋白2(CUL2)、环框蛋白1(RBX1)形成VCR-CB复合物。VCR-CB...
Source LinkDisclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.