智通财经APP讯,中国生物制药(01177)发布公告,CPX102是在IL-29的基础上,经蛋白质工程优化得到的雾化吸入溶液,属于III型干扰素的一种。目前集团正针对该项目在中国开展IIb期临床试验,用于治疗儿童呼吸道合胞病毒(RSV)感染。 CPX102并不直接杀伤或抑制病毒,而是通过诱导细胞表面受体,促使细胞生成抗病毒蛋白,进而抑制病毒的复制。此外,CPX102还能通过调节细胞毒性T淋巴细胞(CTL细胞)、自然杀伤细胞(NK细胞)、巨噬细胞等免疫细胞,激活自身天然免疫,从而起到抗病毒的作用。
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