COPENHAGEN, March 10 (Reuters) - Novo Nordisk said on Monday its experimental next-generation drug CagriSema helped overweight or obese patients with type 2 diabetes cut their weight by 15.7% after 68 weeks.
US-listed shares of Novo Nordisk dropped 8% in morning trading.
The data is seen as crucial for the future potential for its experimental next-generation obesity drug, after results published in December from another trial with the drug in people without diabetes showed lower-than-expected weight loss.
The new data released on Monday from the phase III trial called REDEFINE 2 was based on about 1,200 people with type 2 diabetes and a body mass index (BMI) of or above 27 after 68 weeks.
The REDEFINE 2 trial was based on a flexible protocol, allowing patients to modify their dosing throughout the trial, Novo Nordisk said in a statement.
After 68 weeks, 61.9% of patients treated with CagriSema were on the highest dose, it added.
If all people adhered to treatment with CagriSema, patients overall achieved weight loss of 15.7% after 68 weeks, compared to 31.1% with placebo.
CagriSema is a weekly injection that combines semaglutide, which is the active ingredient in Wegovy and mimics the gut hormone GLP-1, and a separate molecule called cagrilintide that mimics the pancreatic hormone amylin, into a weekly injection.
The two hormones combined suppress hunger and help control patients' blood glucose.
Disclaimer: Investing carries risk. This is not financial advice. The above content should not be regarded as an offer, recommendation, or solicitation on acquiring or disposing of any financial products, any associated discussions, comments, or posts by author or other users should not be considered as such either. It is solely for general information purpose only, which does not consider your own investment objectives, financial situations or needs. TTM assumes no responsibility or warranty for the accuracy and completeness of the information, investors should do their own research and may seek professional advice before investing.