Arvinas和辉瑞的口服PROTAC降解剂vepdegestrant公布3期试验结果

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12 Mar

当地时间3月11日,Arvinas与辉瑞联合宣布其口服PROTAC降解剂vepdegestrant的首个关键3期临床试验结果,并表示这款药物是首个在3期试验中展现出临床益处的PROTAC分子。在携带ESR1突变的激素受体(HR)阳性、HER2阴性乳腺癌患者群体中,vepdegestrant对于患者的无进展生存期(PFS)具有统计显著及临床意义的改善。在包含未携带ESR1突变患者的意向治疗(ITT)...

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