科伦博泰生物-B盘中涨超5% TROP2 ADC芦康沙妥珠单抗第二项适应症获批上市

新浪港股
13 Mar
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  科伦博泰生物-B(06990)盘中涨超5%,截至发稿,股价上涨3.24%,现报242港元,成交额9741.92万港元。

  科伦博泰生物近日公布,公司靶向人滋养细胞表面抗原2(TROP2)的抗体药物偶联物(ADC)芦康沙妥珠单抗(sac-TMT,前称SKB264/MK-2870)(佳泰莱®)获国家药品监督管理局(NMPA)批准第二个适应症,用于治疗经表皮生长因子受体(EGFR)酪氨酸激酶抑制剂(TKI)和含铂化疗治疗后进展的EGFR基因突变阳性的局部晚期或转移性非鳞状非小细胞肺癌(NSCLC)成人患者。这是全球首个在肺癌适应症获批上市的TROP2ADC药物。与目前标准治疗相比,芦康沙妥珠单抗(sac-TMT)显著延长此类患者的总生存获益。

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