重症肌无力(MG)MG发病机制重症肌无力(MG)是一种由乙酰胆碱受体抗体介导的一种获得性神经-肌肉接头(NMJ)传递障碍的器官特异性自身免疫性疾病,临床表现为全身骨骼肌波动性无力与易疲劳,活动后加重,休息后好转;具体症状可表现为呼吸困难、吞咽困难、语言和视力受损。在NMJ,神经通过释放神经递质(i.e乙酰胆碱)与肌肉上的受体相互作用,刺激肌肉收缩。乙酰胆碱受体(AChR)抗体是最常见的致病性抗体,...
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