Sarepta Therapeutics stock falls after DMM patient dies of liver failure

Dow Jones
18 Mar

MW Sarepta Therapeutics stock falls after DMM patient dies of liver failure

Sarepta Therapeutics Inc.'s stock was down 21.6% in premarket trades on Tuesday after the commercial-stage biopharmaceutical company said a patient died from liver failure after using its drug Elevidys, which is used to treat Duchenne muscular dystrophy.

While liver failure is a known possible side effect of Elevidys, it had not yet been reported until now, Sarepta (SRPT) said.

"Acute liver failure leading to death represents a severity of acute liver injury notpreviously reported for Elevidys, which to date has been used to treat more than 800 patients inclinical trials or as a prescribed therapy," the company said.

Prior to Tuesday's moves, Sarepta's stock was down 16.7% so far in 2025, while Nasdaq COMP has dropped 7.8%.

-Steve Gelsi

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March 18, 2025 09:02 ET (13:02 GMT)

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