金吾财讯 | 中信证券指出,PD-L1 ADC药物兼具免疫治疗药物和靶向ADC的双重功效,潜在可触及市场规模有望对标全球超过500亿美元的免疫治疗药物。多个美国市场高发的癌种PD-L1阳性率超过50%。辉瑞公司的PD-L1 ADC已经在NSCLC、HNSCC重度经治人群展现出优异疗效,并且安全性可控,辉瑞预计将在25H2启动2项三期临床,为赛道大幅增加研发确定性。国内复宏汉霖(02696)的PD-L1 ADC已经在2025年前后陆续启动5项二期临床,并且预计其有望在2025年读出一期临床数据。综上,建议关注PD-L1 ADC的临床潜力和商业化价值。
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