Wall Street's main indexes fell on Wednesday as investors worried about the potential impact of U.S. President Donald Trump's sweeping tariffs on the global economy, corporate earnings and inflation. .N

At 11:37 am ET, the Dow Jones Industrial Average .DJI was up 0.38% at 42,149.24. The S&P 500 .SPX was up 0.44% at 5,657.72 and the Nasdaq Composite .IXIC was up 0.56% at 17,547.44.

The top three S&P 500 .PG.INX percentage gainers:

** Moderna Inc MRNA.OQ, up 4.9%

** Caesars Entertainment Inc CZR.OQ, up 4.6%

** Tesla Inc TSLA.OQ, up 4.2%

The top three S&P 500 .PL.INX percentage losers:

** Altria Group Inc MO.N, down 2.9%

** Texas Pacific Land Corp TPL.N, down 2.3%

** Mosaic Co MOS.N, down 2.1%

The top three NYSE .PG.N percentage gainers:

** Rocket Companies Inc RKT.N, up 12.1%

** Babcock & Wilcox Enterprises Inc BW.N, up 9.3%

** Sunnova Energy International Inc NOVA.N, up 9.2%

The top three NYSE .PL.N percentage losers:

** Beachbody Company Inc BODI.N, down 10.9%

** Pacs Group Inc PACS.N, down 8.8%

** BlackBerry Ltd BB.N, down 7.8%

The top three Nasdaq .PG.O percentage gainers:

** Innovation Beverage Group Ltd IBG.OQ, up 146.4%

** Digital Ally Inc DGLY.OQ, up 139.6%

** American Rebel Holdings Inc AREB.OQ, up 128.9%

The top three Nasdaq .PL.O percentage losers:

** Jayud Global Logistics Ltd JYD.OQ, down 93.5%

** ReShape Lifesciences Inc RSLS.OQ, down 68.8%

** BingEx Ltd FLX.OQ, down 53.7%

** Grifols SA <GRFS.O>:

BUZZ - Jumps after report of Brookfield resuming takeover talks nL5N3QG08O

** SmartStop Self-Storage REIT Inc <SMA.N>:

BUZZ - Set to open above offer price in NYSE debut after $810 million IPO nL6N3QG0M5

** Newsmax Inc <NMAX.N>:

BUZZ - Stock takes breather after staggering rally nL6N3QG0LC

** Charles Schwab Corp <SCHW.N>:

BUZZ - Rises after Citi upgrades to 'buy' nL3N3QF188

** CenterPoint Energy Inc <CNP.N>:

BUZZ - Jefferies starts coverage on CenterPoint Energy with 'buy' rating nL3N3QG0LC

** nCino Inc <NCNO.O>:

BUZZ - Plummets after annual outlook, Q4 EPS miss nL6N3QG0G6

** Comerica Inc <CMA.N>:

BUZZ - Raymond James cuts Comerica price target to $67 nL6N3QG0GH

** Beacon Roofing Supply Inc <BECN.O>:

BUZZ - RBC cuts Beacon Roofing Supply rating on QXO offer price nL3N3QG0MD

** Truist Financial Corp <TFC.N>:

BUZZ - Falls on Raymond James cut to "market perform" nL6N3QG0GW

** Sitio Royalties Corp <STR.N>:

BUZZ - Mizuho starts coverage on Sitio Royalties with 'neutral' rating nL3N3QG0NB

** WesBanco Inc <WSBC.O>:

BUZZ - Raymond James cuts WesBanco PT on Premier Financial acquisition closing delays nL6N3QG0HC

** Robinhood Markets Inc <HOOD.O>:

BUZZ - Citigroup lowers Robinhood PT on crypto pullback nL6N3QG0HO

** Corebridge Financial Inc <CRBG.N>:

BUZZ - Slides after UBS downgrades to 'sell', cuts PT nL3N3QG0OU

** Morgan Stanley <MS.N>:

BUZZ - BofA cuts Morgan Stanley PT citing seasonal challenges nL6N3QG0HV

** Paramount Global <PARA.O>:

BUZZ - Falls after Deutsche Bank downgrades rating, cuts PT nL3N3QG0P4

** Greenwich LifeSciences Inc <GLSI.O>:

BUZZ - Rises on immune response data from breast cancer therapy trial nL6N3QG0HR

** CoreWeave Inc <CRWV.O>:

BUZZ - Shares resume stunning rally nL6N3QG0M6

** Raymond James Financial Inc <RJF.N>:

BUZZ - Citi cuts Raymond James PT citing market volatility, tariff uncertainty nL6N3QG0IK

** Webster Financial Corp WBS.N:

BUZZ - Raymond James cuts Webster Financial PT on conservative growth outlook nL6N3QG0IQ

** Waton Financial Ltd <WTF.O>:

BUZZ - Slumps after near five-fold gain on Nasdaq debut nL6N3QG0LB

** Blackberry Ltd <BB.N>:

BUZZ - Plunges on gloomy annual revenue forecast nL3N3QG0WD

** United Airlines Holdings Inc <UAL.O>:

BUZZ - Falls after Raymond James cuts rating on earnings risk nL3N3QG0QU

** Rivian Automotive Inc <RIVN.O>:

BUZZ - Falls after reporting decline in first-quarter deliveries nL3N3QG0WM

** Molson Coors Beverage Co <TAP.N>:

** Diageo PLC <DGE.N>:

** Boston Beer Company Inc <SAM.N>:

** Brown-Forman Corp <BFb.N>:

BUZZ - Berenberg prefers beer and soft drinks over spirits in 2025 nL5N3QG0H3

** South State Corp <SSB.N>:

BUZZ - Raymond James upgrades SouthState to 'strong buy', cuts PT nL6N3QG0JQ

** Idacorp Inc <IDA.N>:

BUZZ - Jefferies upgrades Idacorp to 'buy', predicts robust assets value growth nL6N3QG0J9

** Tesla Inc <TSLA.O>:

BUZZ - Falls as Q1 deliveries miss estimates nL3N3QG0XH

** Coinbase Global Inc <COIN.O>:

** Riot Platforms Inc <RIOT.O>:

** MARA Holdings Inc <MARA.O>:

** Hut 8 Corp <HUT.O>:

BUZZ - Crypto stocks track weak bitcoin lower nL6N3QG0K0

** Marex Group PLC <MRX.O>:

BUZZ - Rises after Q1 prelim results nL6N3QG0JP

** Allakos Inc <ALLK.O>:

BUZZ - Soars on buyout deal with Concentra Biosciences nL6N3QG0K4

** Norwegian Cruise Line Holdings Ltd <NCLH.N>:

BUZZ - Shares down after exchangeable debt refinancing nL6N3QG0KG

** Third Coast Bancshares Inc <TCBX.O>:

BUZZ - Raymond James downgrades Third Coast to "market perform" on growth slowdown nL6N3QG0KM

** M-tron Industries Inc <MPTI.N>:

BUZZ - Rises on $12 million aircraft component contract nL3N3QG0W8

** Edgewise Therapeutics Inc <EWTX.O>:

BUZZ - Falls on safety, efficacy doubts for heart disease drug nL6N3QG0G5

** Rocket Companies Inc <RKT.N>:

BUZZ - Jumps after brokerages upgrade rating on stock nL3N3QG0PN

** TKO Group Holdings Inc <TKO.N>:

BUZZ - Rises on unit UFC's deal with Meta nL3N3QG0YI

** Petco Health and Wellness Company Inc <WOOF.O>:

BUZZ - Jumps after CEO discloses stock purchase nL6N3QG0LT

** Trump Media & Technology Group Corp <DJT.O>:

BUZZ - Falls after report of potential $2.3 billion stake sale nL3N3QG0ST

** Nasdaq Inc <NDAQ.O>:

BUZZ - BofA raises Nasdaq PT citing index revenue and pricing tailwinds nL6N3QG0M7

** Astrana Health Inc <ASTH.O>:

BUZZ - Barclays initiates Astrana Health, noting risks on pending acquisition nL3N3QG0YP

** CME Group Inc <CME.O>:

BUZZ - BofA raises exchange operator CME PT citing macroeconomic and retail factors nL6N3QG0NK

(Compiled by Rajarshi Roy and Aatreyee Dasgupta)

((Rajarshi.Roy@thomsonreuters.com))