Updates

** Shares of drugmaker Eli Lilly LLY.N rise 12.7% to $828.67 premarket

** Company says its small molecule oral drug orforglipron led to an average weight loss of 7.9% and lowered blood sugar for overweight patients with type 2 diabetes in a late-stage trial

** Shares of Structure Therapeutics GPCR.O, which is also developing a small molecule oral weight loss drug, gain 17.7% before the bell

** U.S.-listed shares of Lilly's obesity drug rival Novo Nordisk NOVOb.CO down 6%

** Other weight-loss drug developers such as Viking Therapeutics VKTX.O down 5.1% and Amgen AMGN.O down 2.8%

** Up to last close, LLY shares down 4.8%, VKTX down 41.2% YTD

(Reporting by Christy Santhosh in Bengaluru)

((Christy.Santhosh@thomsonreuters.com))