PLoS One:免疫疗法可显著改善儿童1型糖尿病患者的血糖水平,但胰岛功能改善尚待观察

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该研究通过Meta分析评估了免疫疗法对1型糖尿病(T1DM)患者的C肽、HbA1c及胰岛素剂量的影响。结果显示,免疫治疗显著降低了HbA1c水平(MD=-0.63,p=0.03),但对C肽水平的改善无统计学意义(MD=1.51,p=0.42)。不同免疫疗法的效果存在差异,如Anakinra显著提升C肽水平并降低HbA1c,而Canakinumab则降低C肽水平。总体而言,免疫疗法在改善血糖控制方面...

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