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Lexicon Pharmaceuticals

0.5098

+0.00981.96%

Post-market: 0.51000.0002+0.04%19:59 EDT

Volume:2.67M

Turnover:1.36M

Market Cap:184.29M

PE:-0.81

High:0.5262

Open:0.5001

Low:0.4980

Close:0.5000

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Overview Company News Filings

Lexicon Pharmaceuticals Inc : Leerink Partners Cuts Target Price to $4 From $5

THOMSON REUTERS

Lexicon Pharmaceuticals (LXRX) Gets a Buy from Piper Sandler

Lexicon Pharma Price Target Maintained With a $6.00/Share by HC Wainwright & Co.

Lexicon Pharmaceuticals Inc (LXRX) Q3 2024 Earnings Call Highlights: Strategic Advances Amidst ...

Lexicon Pharmaceuticals Inc reports results for the quarter - Earnings Summary

Lexicon Pharmaceuticals (LXRX) Reports Q3 Loss, Lags Revenue Estimates

Lexicon: Q3 Earnings Snapshot

Associated Press Finance

Lexicon Pharmaceuticals Q3 2024 GAAP EPS $(0.18) Misses $(0.17) Estimate, Sales $1.800M Miss $2.929M Estimate

Lexicon Pharmaceuticals options imply 14.8% move in share price post-earnings

Lexicon Pharmaceuticals Inc expected to post a loss of 16 cents a share - Earnings Preview

Lexicon Pharmaceuticals to Participate in the Jefferies London Global Healthcare Conference

Lexicon announces JASN publishes sotagliflozin data

Published Data in Journal of American Society of Nephrology Highlights Findings on Efficacy and Safety of Sotagliflozin for People With Type 1 Diabetes and Chronic Kidney Disease

Lexicon Pharma Price Target Maintained With a $6.00/Share by HC Wainwright & Co.

Lexicon Pharmaceuticals to Host Third Quarter 2024 Financial Results Conference Call and Webcast on November 12, 2024

Lexicon Pharmaceuticals Inc expected to post a loss of 16 cents a share - Earnings Preview

BRIEF-Lexicon To Present Preclinical In Vivo Efficacy Data Demonstrating Ability Of New Investigational Compound To Enhance And Maintain Semaglutide-Promoted Weight Loss

Lexicon to Present Preclinical in Vivo Efficacy Data Demonstrating Ability of New Investigational Compound to Enhance and Maintain Semaglutide-Promoted Weight Loss

THOMSON REUTERS

Lexicon to Present Preclinical IN VIVO Efficacy Data Demonstrating Ability of New Investigational Compound to Enhance and Maintain Semaglutide-Promoted Weight Loss

Top Midday Decliners

MT Newswires Live

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Pharmaceuticals Inc : Leerink Partners Cuts Target Price to $4 From $5","url":"https://stock-news.laohu8.com/highlight/detail?id=2483878243","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483878243?lang=en_us&edition=fundamental","pubTime":"2024-11-14 19:30","pubTimestamp":1731583811,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241114:nFWN3ML0NA:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LXRX","BK4139"],"gpt_icon":0},{"id":"2483894000","title":"Lexicon Pharmaceuticals (LXRX) Gets a Buy from Piper 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Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2483606211","media":"Reuters","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483606211?lang=en_us&edition=fundamental","pubTime":"2024-11-13 07:27","pubTimestamp":1731454034,"startTime":"0","endTime":"0","summary":"* Lexicon Pharmaceuticals Inc    reported a quarterly adjusted loss of 18 cents per share for the quarter , higher than the same quarter last year, when the company reported EPS of -21 cents.  The mea","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LXRX"],"gpt_icon":0},{"id":"2483094560","title":"Lexicon Pharmaceuticals (LXRX) Reports Q3 Loss, Lags Revenue Estimates","url":"https://stock-news.laohu8.com/highlight/detail?id=2483094560","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483094560?lang=en_us&edition=fundamental","pubTime":"2024-11-13 06:25","pubTimestamp":1731450305,"startTime":"0","endTime":"0","summary":"Lexicon Pharmaceuticals  came out with a quarterly loss of $0.18 per share versus the Zacks Consensus Estimate of a loss of $0.17. This compares to loss of $0.21 per share a year ago. These figures are adjusted for non-recurring items.This quarterly report represents an earnings surprise of -5.88%. A quarter ago, it was expected that this drugmaker would post a loss of $0.18 per share when it actually produced a loss of $0.17, delivering a surprise of 5.56%.Over the last four quarters, the company has surpassed consensus EPS estimates two times.Lexicon , which belongs to the Zacks Medical - Biomedical and Genetics industry, posted revenues of $1.75 million for the quarter ended September 2024, missing the Zacks Consensus Estimate by 44.18%. This compares to year-ago revenues of $0.16 million. The company has topped consensus revenue estimates just once over the last four quarters.Investors should be mindful of the fact that the outlook for the industry can have a material impact on the","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/26ddEdIk.0DefsBmi91u3Q--~B/aD01OTg7dz05MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/21b1f011539d3e31c28282071d344177","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/26ddEdIk.0DefsBmi91u3Q--~B/aD01OTg7dz05MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/21b1f011539d3e31c28282071d344177"],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/lexicon-pharmaceuticals-lxrx-reports-q3-222505799.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LXRX"],"gpt_icon":0},{"id":"2483050828","title":"Lexicon: Q3 Earnings Snapshot","url":"https://stock-news.laohu8.com/highlight/detail?id=2483050828","media":"Associated Press Finance","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483050828?lang=en_us&edition=fundamental","pubTime":"2024-11-13 05:25","pubTimestamp":1731446732,"startTime":"0","endTime":"0","summary":"THE WOODLANDS, Texas  — THE WOODLANDS, Texas  — Lexicon Pharmaceuticals Inc.  on Tuesday reported a loss of $64.8 million in its third quarter.On a per-share basis, the The Woodlands, Texas-based company said it had a loss of 18 cents.The results missed Wall Street expectations. The average estimate of four analysts surveyed by Zacks Investment Research was for a loss of 17 cents per share.The drugmaker posted revenue of $1.8 million in the period, also missing Street forecasts. Four analysts surveyed by Zacks expected $3.1 million.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/lexicon-q3-earnings-snapshot-212532650.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LXRX"],"gpt_icon":0},{"id":"2483105291","title":"Lexicon Pharmaceuticals Q3 2024 GAAP EPS $(0.18) Misses $(0.17) Estimate, Sales $1.800M Miss $2.929M Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2483105291","media":"Benzinga","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483105291?lang=en_us&edition=fundamental","pubTime":"2024-11-13 05:08","pubTimestamp":1731445698,"startTime":"0","endTime":"0","summary":"Lexicon Pharmaceuticals (NASDAQ:LXRX) reported quarterly losses of $(0.18) per share which missed the analyst consensus estimate of $(0.17) by 5.88 percent.  The company reported quarterly sales of $1.800 million which","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/24/11/41919052/lexicon-pharmaceuticals-q3-2024-gaap-eps-0-18-misses-0-17-estimate-sales-1-800m-miss-2-929m-estimat","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":"Lexicon Pharmaceuticals Q3 2024 GAAP EPS $(0.18) Misses $(0.17) Estimate, Sales $1.800M Miss $2.929M Estimate","news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LXRX"],"gpt_icon":0},{"id":"2483676054","title":"Lexicon Pharmaceuticals options imply 14.8% move in share price post-earnings","url":"https://stock-news.laohu8.com/highlight/detail?id=2483676054","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2483676054?lang=en_us&edition=fundamental","pubTime":"2024-11-13 04:30","pubTimestamp":1731443424,"startTime":"0","endTime":"0","summary":"Pre-earnings options volume in Lexicon (LXRX) Pharmaceuticals is normal with calls leading puts 11:2. Implied volatility suggests the market is ant...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/lexicon-pharmaceuticals-options-imply-14-8-move-in-share-price-post-earnings?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/lexicon-pharmaceuticals-options-imply-14-8-move-in-share-price-post-earnings?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LXRX"],"gpt_icon":0},{"id":"2482469198","title":"Lexicon Pharmaceuticals Inc  expected to post a loss of 16 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2482469198","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2482469198?lang=en_us&edition=fundamental","pubTime":"2024-11-09 08:26","pubTimestamp":1731111965,"startTime":"0","endTime":"0","summary":"Lexicon Pharmaceuticals Inc  expected to post a loss of16cents a share - Earnings Preview Lexicon Pharmaceuticals Inc LXRX.OQ LXRX.O is expected to show a rise in quarterly revenue when it reports  re","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241109:nL8N3MG02E:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LXRX"],"gpt_icon":0},{"id":"2481606066","title":"Lexicon Pharmaceuticals to Participate in the Jefferies London Global Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2481606066","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481606066?lang=en_us&edition=fundamental","pubTime":"2024-11-06 21:00","pubTimestamp":1730898000,"startTime":"0","endTime":"0","summary":"THE WOODLANDS, Texas, Nov.  06, 2024  (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced its participation in the Jefferies London Global Healthcare Conference. Lexicon m","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/11/06/2975653/0/en/Lexicon-Pharmaceuticals-to-Participate-in-the-Jefferies-London-Global-Healthcare-Conference.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4137","HCSG","LXRX"],"gpt_icon":0},{"id":"2481652264","title":"Lexicon announces JASN publishes sotagliflozin data","url":"https://stock-news.laohu8.com/highlight/detail?id=2481652264","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481652264?lang=en_us&edition=fundamental","pubTime":"2024-11-06 05:50","pubTimestamp":1730843419,"startTime":"0","endTime":"0","summary":"Lexicon (LXRX) announced the peer-reviewed Journal of American Society of Nephrology, or JASN, has published a research paper analyzing the efficac...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/lexicon-announces-jasn-publishes-sotagliflozin-data?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/lexicon-announces-jasn-publishes-sotagliflozin-data?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LXRX","BK4139"],"gpt_icon":0},{"id":"2481022656","title":"Published Data in Journal of American Society of Nephrology Highlights Findings on Efficacy and Safety of Sotagliflozin for People With Type 1 Diabetes and Chronic Kidney Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2481022656","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481022656?lang=en_us&edition=fundamental","pubTime":"2024-11-06 05:05","pubTimestamp":1730840700,"startTime":"0","endTime":"0","summary":"People with T1D and CKD treated with sotagliflozin and insulin had similar lowering effects on glycated hemoglobin , the primary endpoint, as people with T1D who do not have CKD. Sotagliflozin was associated with a lower to neutral risk of severe hypoglycemia and did not significantly increase the risk of diabetic ketoacidosis  among a small number of DKA events. The findings from the study, “Efficacy and Safety of Sotagliflozin in Patients with Type 1 Diabetes and CKD,” concluded that people with T1D and CKD treated with sotagliflozin and insulin had similar lowering effects on glycated hemoglobin , the primary endpoint of the underlying clinical trials, as T1D patients who do not have CKD. Further, the findings show that sotagliflozin was associated with a lower to neutral risk of severe hypoglycemia and did not significantly increase the risk of diabetic ketoacidosis  among a small number of DKA events.Results were generally similar in inTandem3 except systolic BP was significantly ","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/z4OL.khIWMuwruXdjunukQ--~B/aD01MDt3PTE2NjthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/globenewswire.com/0ead9423451a49118cdc67bcbc937222","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/z4OL.khIWMuwruXdjunukQ--~B/aD01MDt3PTE2NjthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/globenewswire.com/0ead9423451a49118cdc67bcbc937222"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/published-data-journal-american-society-210500951.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4585","BK4139","LU0320765646.SGD","LU1829250122.USD","BK4107","BK4588","BP","LU0162691827.USD","LU1162221912.USD","LXRX","BK4117","BK4201","AFG","LU0072461881.USD"],"gpt_icon":0},{"id":"2481068334","title":"Lexicon Pharma Price Target Maintained With a $6.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2481068334","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481068334?lang=en_us&edition=fundamental","pubTime":"2024-11-05 22:57","pubTimestamp":1730818620,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/LXRX/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 05, 2024 09:57 ET (14:57 GMT)","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LXRX"],"gpt_icon":0},{"id":"2481506297","title":"Lexicon Pharmaceuticals to Host Third Quarter 2024 Financial Results Conference Call and Webcast on November 12, 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2481506297","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481506297?lang=en_us&edition=fundamental","pubTime":"2024-11-05 21:00","pubTimestamp":1730811600,"startTime":"0","endTime":"0","summary":"THE WOODLANDS, Texas, Nov.  05, 2024  (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) will release its third quarter 2024 financial results on Tuesday, November 12, 2024 after the mar","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/11/05/2974885/0/en/Lexicon-Pharmaceuticals-to-Host-Third-Quarter-2024-Financial-Results-Conference-Call-and-Webcast-on-November-12-2024.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","HST","BK4139","BK4218","LXRX","BK4588","BK4181"],"gpt_icon":0},{"id":"2480580525","title":"Lexicon Pharmaceuticals Inc    expected to post a loss of 16 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2480580525","media":"Reuters","labels":["preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480580525?lang=en_us&edition=fundamental","pubTime":"2024-11-04 23:38","pubTimestamp":1730734701,"startTime":"0","endTime":"0","summary":"* Lexicon Pharmaceuticals Inc     is expected to show a rise in quarterly revenue when it reports  results on November 6 (estimated) for the period ending September 30 2024   * The The Woodlands Texas","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Lexicon Pharmaceuticals Inc    expected to post a loss of 16 cents a share - Earnings Preview","news_tag":"preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LXRX"],"gpt_icon":0},{"id":"2480896105","title":"BRIEF-Lexicon To Present Preclinical In Vivo Efficacy Data Demonstrating Ability Of New Investigational Compound To Enhance And Maintain Semaglutide-Promoted Weight Loss","url":"https://stock-news.laohu8.com/highlight/detail?id=2480896105","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480896105?lang=en_us&edition=fundamental","pubTime":"2024-11-04 22:28","pubTimestamp":1730730538,"startTime":"0","endTime":"0","summary":"Nov 4 (Reuters) - Lexicon Pharmaceuticals Inc   :   * LEXICON TO PRESENT PRECLINICAL IN VIVO EFFICACY DATA DEMONSTRATING ABILITY OF NEW INVESTIGATIONAL COMPOUND TO ENHANCE AND MAINTAIN SEMAGLUTIDE-PROMOTED WEIGHT LOSSSource text:    Further company coverage:    (Reuters.Briefs@thomsonreuters.com)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LXRX","ABIL"],"gpt_icon":0},{"id":"2480729307","title":"Lexicon to Present Preclinical in Vivo Efficacy Data Demonstrating Ability of New Investigational Compound to Enhance and Maintain Semaglutide-Promoted Weight Loss","url":"https://stock-news.laohu8.com/highlight/detail?id=2480729307","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480729307?lang=en_us&edition=fundamental","pubTime":"2024-11-04 21:00","pubTimestamp":1730725210,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241104:nFWN3MB0Q6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["LXRX","BK4139"],"gpt_icon":0},{"id":"2480130010","title":"Lexicon to Present Preclinical IN VIVO Efficacy Data Demonstrating Ability of New Investigational Compound to Enhance and Maintain Semaglutide-Promoted Weight Loss","url":"https://stock-news.laohu8.com/highlight/detail?id=2480130010","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480130010?lang=en_us&edition=fundamental","pubTime":"2024-11-04 21:00","pubTimestamp":1730725200,"startTime":"0","endTime":"0","summary":"Investigational New Drug  application planned in 2025 for LX9851, afirst-in-class, potent, selective, orally bioavailable molecule, as an anti-obesity agent. Preclinical in vivo efficacy data from the first study showed that treatment with LX9851 resulted in significant reductions in weight, food intake and fat mass in diet-induced obese  mice. Among other important findings, LX9851 mitigated weight regain following discontinuation of the GLP-1 analogue semaglutide. This study  investigated the body-weight reduction and weight maintenance effects of Lexicon’s first-in-class small molecule ACSL5 inhibitor, as a monotherapy and in combination with semaglutide, in a DIO mouse model. On Day 28, fat and lean body mass were measured by DEXA . All treatments with LX9851 resulted in a reduction in fat mass compared to vehicle control. The greatest weight reduction with no significant effect on lean body mass was observed when LX9851 was combined with semaglutide. The combination therapy also r","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/z4OL.khIWMuwruXdjunukQ--~B/aD01MDt3PTE2NjthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/globenewswire.com/0ead9423451a49118cdc67bcbc937222","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/z4OL.khIWMuwruXdjunukQ--~B/aD01MDt3PTE2NjthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/globenewswire.com/0ead9423451a49118cdc67bcbc937222"],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/lexicon-present-preclinical-vivo-efficacy-130000394.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["ABIL","LXRX","VIVO"],"gpt_icon":0},{"id":"2480853258","title":"Top Midday Decliners","url":"https://stock-news.laohu8.com/highlight/detail?id=2480853258","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480853258?lang=en_us&edition=fundamental","pubTime":"2024-11-02 02:16","pubTimestamp":1730484970,"startTime":"0","endTime":"0","summary":"ESSA Pharma  said late Thursday it decided to terminate the phase 2 trial evaluating the combination of masofaniten and enzalutamide in patients with metastatic castration-resistant prostate cancer compared with enzalutamide alone.Shares slumped 71%, with intraday trading volume at over 27.6 million compared with a daily average of about 59,000.Lexicon Pharmaceuticals  said late Thursday that the Endocrinologic and Metabolic Drugs Advisory Committee of the US Food and Drug Administration voted 11-3 against recommending Zynquista  as an add-on to insulin therapy for glycemic control in adults suffering from type 1 diabetes and chronic kidney disease.Shares sank 37% as intraday trading volume catapulted to more than 16.8 million from a daily average of about 2.7 million.Autonomix Medical  unveiled Friday the launch of a public offering of up to 698,812 common stock units at $14.31 each.Shares retreated 24%, with intraday trading volume at over 341,000 versus a daily average of roughly 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