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Activity Index Rises In December","url":"https://stock-news.laohu8.com/highlight/detail?id=2506308445","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506308445?lang=en_us&edition=fundamental","pubTime":"2025-01-27 22:43","pubTimestamp":1737989032,"startTime":"0","endTime":"0","summary":" 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Monday","url":"https://stock-news.laohu8.com/highlight/detail?id=2506550370","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506550370?lang=en_us&edition=fundamental","pubTime":"2025-01-27 22:11","pubTimestamp":1737987112,"startTime":"0","endTime":"0","summary":"Health care stocks were mixed premarket Monday, with The Health Care Select Sector SPDR Fund  up 0.4% and the iShares Biotechnology ETF  0.3% lower.Akero Therapeutics  shares were up over 110% after the company said a phase 2b study of its lead product candidate efruxifermin showed a \"statistically significant\" reversal of compensated cirrhosis caused by metabolic dysfunction-associated steatohepatitis, or MASH.Allakos  stock was down past 73% after the company said its phase 1 trial of AK006 in chronic spontaneous urticaria failed to demonstrate therapeutic efficacy and its development will be terminated immediately.Innate Pharma  shares were up over 7% after the company said it has dosed its first patient in a phase 1 study to investigate the safety and tolerability of IPH4502, an antibody-drug conjugate for the potential treatment of patients with advanced solid tumors known to express Nectin-4.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["ALLK","AKRO","BK4139","XLV","BK4581","IBB","BK4505","BK4585","IPHA","BK4588"],"gpt_icon":0},{"id":"2506377071","title":"Chinese AI Platform Fuels Jitters on Wall Street, Driving Premarket Losses for US Equity Futures","url":"https://stock-news.laohu8.com/highlight/detail?id=2506377071","media":"MT Newswires 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Why","url":"https://stock-news.laohu8.com/highlight/detail?id=2506469370","media":"Benzinga","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506469370?lang=en_us&edition=fundamental","pubTime":"2025-01-27 22:01","pubTimestamp":1737986519,"startTime":"0","endTime":"0","summary":"On Monday, Akero Therapeutics, Inc. released preliminary topline week 96 results from SYMMETRY Phase 2b study evaluating the efficacy and safety of its lead product candidate efruxifermin  in patients with biopsy-confirmed compensated cirrhosis , Child-Pugh Class A, due to metabolic dysfunction-associated steatohepatitis .Among patients with baseline and week 96 biopsies , 39% of patients treated with 50mg EFX  experienced reversal of cirrhosis with no worsening of MASH, representing a 24% effect size over placebo at 15% .In the Intent to Treat  population , with all missing week 96 biopsies treated as failures, 29% of patients in the 50mg EFX group  experienced reversal of cirrhosis with no worsening of MASH, representing a 17% effect size over placebo at 12% .With more than a doubling of effect size from weeks 36 to 96 in the 50mg group , the SYMMETRY study underscores the benefit of longer EFX treatment for patients with compensated cirrhosis .","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/liver-disease-focused-akero-therapeutics-140159595.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["EFX","LU0054578231.USD","BK4161","LU0053671581.USD","BK4123","AKRO","BK4588","BK4139","ITT","BK4505","BK4585"],"gpt_icon":0},{"id":"2506337722","title":"Akero Therapeutics MASH data ‘best-case-scenario,’ says Citi","url":"https://stock-news.laohu8.com/highlight/detail?id=2506337722","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506337722?lang=en_us&edition=fundamental","pubTime":"2025-01-27 21:46","pubTimestamp":1737985594,"startTime":"0","endTime":"0","summary":"Citi analyst Jonathan Woo says Akero Therapeutics (AKRO)’ 96-week data update from its SYMMETRY trial of efruxifermin for patients with compensated...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/akero-therapeutics-mash-data-best-case-scenario-says-citi?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/akero-therapeutics-mash-data-best-case-scenario-says-citi?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4505","AKRO","BK4588","BK4139","BK4585"],"gpt_icon":0},{"id":"2506837236","title":"Exchange-Traded Funds, Equity Futures Lower Pre-Bell Monday as China's DeepSeek Disrupts Tech Sector","url":"https://stock-news.laohu8.com/highlight/detail?id=2506837236","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506837236?lang=en_us&edition=fundamental","pubTime":"2025-01-27 21:28","pubTimestamp":1737984504,"startTime":"0","endTime":"0","summary":"The broad market exchange-traded fund SPDR S&P 500 ETF Trust (SPY) was down 2.1% and the actively traded Invesco QQQ Trust (QQQ) fell 4% in Monday's premarket activity, on rising investor concerns ove","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IPK","IYH","IGV","IYK","PMR","JG","XLK",".IXIC","RTH","XLI","EEM","BITO","USO","SLV","XLF","FAS","XLE","EQR","RYAAY","DEC",".SPX","VIS","XLV","BAM","VDC","EXI","IVV","VHT","IYW","XLY","FAZ",".DJI","IYE","XSD","QQQ","SOXX","AKRO","DADA","GLD","IYJ","XRT","SPY","IBB","XLP","UNG","IGM"],"gpt_icon":1},{"id":"2506371656","title":"Akero Therapeutics Says Phase 2b Efruxifermin Study Shows 'Statistically Significant' Reversal of Cirrhosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2506371656","media":"MT Newswires 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In the intent-to-treat group, 29% of patients treated achieved reversal, compared with about 12% for placebo, the company added.Efruxifermin was well-tolerated, with no deaths in the treatment groups and most side effects being mild, transient, and gastrointestinal in nature, according to Akero.The company said it is advancing its evaluation of efruxifermin in an ongoing phase 3 trial.The company's shares soared past 115% in recent Monday premarket activity.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["AKRO","BK4505","BK4139","BK4585","BK4588"],"gpt_icon":0},{"id":"2506379586","title":"Akero soars as drug shows it reverses scarring in liver disease patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2506379586","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506379586?lang=en_us&edition=fundamental","pubTime":"2025-01-27 20:25","pubTimestamp":1737980750,"startTime":"0","endTime":"0","summary":"UPDATE 3-Akero soars as drug shows it reverses scarring in liver disease patientsUpdates share move in paragraphs 1 and 8, adds analyst comment in paragraph 7By Sriparna  Roy","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250127:nL3N3ON0PJ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2063271972.USD","LU1093756325.SGD","LLY","LU0256863902.USD","LU2361045086.USD","LU2468319806.SGD","IE0004445239.USD","LU0354030438.USD","LU2324357040.USD","LU1061106388.HKD","LU0094547139.USD","LU1267930730.SGD","LU0256863811.USD","LU1551013425.SGD","SG9999015986.USD","LU0203202063.USD","LU2237443382.USD","LU1057294990.SGD","LU2112291526.USD","LU2211815571.USD","IE00BFTCPJ56.SGD","LU1988902786.USD","LU2237443465.HKD","LU2237443895.HKD","LU0471298694.HKD","LU1280957306.USD","LU0320765059.SGD","LU0943347566.SGD","IE00BJJMRZ35.SGD","LU0820561909.HKD","IE00B1BXHZ80.USD","AKRO","SG9999018857.SGD","LU0006306889.USD","BK4534","LU1804176565.USD","LU1720051017.SGD","LU0238689110.USD","LU1868837300.USD","LU1974910355.USD","BK4581","SG9999001176.USD","LU2264538146.SGD","LU2023250504.SGD","LU2237443549.SGD","LU1917777945.USD","LU1868836757.USD","LU2265009873.SGD","LU0122379950.USD","LU0289739699.SGD"],"gpt_icon":1},{"id":"2506376578","title":"Akero Therapeutics Shares Double After Positive Study Results for Efruxifermin","url":"https://stock-news.laohu8.com/highlight/detail?id=2506376578","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506376578?lang=en_us&edition=fundamental","pubTime":"2025-01-27 19:59","pubTimestamp":1737979140,"startTime":"0","endTime":"0","summary":"Akero Therapeutics shares doubled to $55.64 in premarket trading after the company said it saw positive preliminary topline results from its Phase 2b study evaluating the efficacy and safety of its lead product candidate, efruxifermin.The company said that efruxifermin is for use in patients with biopsy-confirmed compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis.Among patients with baseline and week 96 biopsies, 39% of patients treated with 50 milligrams experienced reversal of cirrhosis with no worsening of MASH, compared to 15% for placebo.In a subgroup of patients with baseline and week 96 biopsies who were not taking GLP-1 at baseline, 45% in the 50 milligram efruxifermin group experienced reversal of cirrhosis with no worsening of MASH, compared to 17% for placebo, suggesting that the observed reversal of cirrhosis was not attributable to GLP-1 therapy.Efruxifermin was reported to be generally well-tolerated. There were no deaths on efruxifermin, but on","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":"Akero Therapeutics Shares Double After Positive Study Results for Efruxifermin","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","BK4505","BK4585","BK4139","AKRO"],"gpt_icon":0},{"id":"2506665375","title":"Akero shares double after preliminary results from mid-stage trial for liver disease drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2506665375","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506665375?lang=en_us&edition=fundamental","pubTime":"2025-01-27 19:48","pubTimestamp":1737978539,"startTime":"0","endTime":"0","summary":"Akero shares double after preliminary results from mid-stage trial for liver disease drugJan 27  - Akero Therapeutics AKRO.O shares gained 106% before the bell on Monday after the company reported results from a mid-stage trial studying its lead drug in patients with a type of liver disease.The experimental drug efruxifermin is being studied in patients with scarring due to a type of fatty liver disease known as metabolic dysfunction-associated steatohepatitis.  ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250127:nL3N3ON0P2:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AKRO","BK4588","BK4139","BK4585","BK4505"],"gpt_icon":0},{"id":"2506375348","title":"Akero Therapeutics Shares Double Pre-Bell After Preliminary Results From Phase 2b Trial of Lead Product Candidate","url":"https://stock-news.laohu8.com/highlight/detail?id=2506375348","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506375348?lang=en_us&edition=fundamental","pubTime":"2025-01-27 19:48","pubTimestamp":1737978490,"startTime":"0","endTime":"0","summary":"Akero Therapeutics Shares Double Pre-Bell After Preliminary Results From Phase 2b Trial of Lead Product Candidate","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4588","BK4505","BK4585","BK4139","AKRO"],"gpt_icon":0},{"id":"2506373773","title":"Akero Therapeutics Shares Jump 91% Premarket After Co Reports Prelim Mid-Stage Data on Liver Disease Drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2506373773","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506373773?lang=en_us&edition=fundamental","pubTime":"2025-01-27 19:43","pubTimestamp":1737978214,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250127:nL3N3ON0OZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4505","AKRO","BK4588","BK4139","BK4585"],"gpt_icon":0},{"id":"2506735653","title":"Akero Therapeutics Reports Preliminary Topline Results Showing Statistically Significant Reversal of Compensated Cirrhosis (F4) Due to Mash—by Both Completer and ITT Analyses—at Week 96 in Phase 2B Symmetry Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2506735653","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506735653?lang=en_us&edition=fundamental","pubTime":"2025-01-27 19:30","pubTimestamp":1737977404,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250127:nFWN3OL088:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4505","BK4585","BK4588","AKRO"],"gpt_icon":0},{"id":"2506929373","title":"Akero Therapeutics Reports Preliminary Topline Results Showing Statistically Significant Reversal of Compensated Cirrhosis (F4) Due to MASH—by Both Completer and ITT Analyses—at Week 96 in Phase 2b SYMMETRY Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2506929373","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506929373?lang=en_us&edition=fundamental","pubTime":"2025-01-27 19:30","pubTimestamp":1737977400,"startTime":"0","endTime":"0","summary":"Among patients with baseline and week 96 biopsies, 39% of the 50mg EFX group (p=0.009) demonstrated ≥1 stage improvement in fibrosis with no worsening of MASH, representing a 24% effect size over plac","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/01/27/3015438/0/en/Akero-Therapeutics-Reports-Preliminary-Topline-Results-Showing-Statistically-Significant-Reversal-of-Compensated-Cirrhosis-F4-Due-to-MASH-by-Both-Completer-and-ITT-Analyses-at-Week.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ITT","LU0054578231.USD","BK4505","BK4588","EFX","BK4161","LU0053671581.USD","BK4123","BK4139","BK4585","AKRO"],"gpt_icon":0},{"id":"2506481345","title":"Akero Therapeutics to Present Preliminary Topline Week 96 Results from Phase 2b SYMMETRY Study Investigating Efruxifermin in Patients with Compensated Cirrhosis (F4) Due to MASH","url":"https://stock-news.laohu8.com/highlight/detail?id=2506481345","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506481345?lang=en_us&edition=fundamental","pubTime":"2025-01-25 05:05","pubTimestamp":1737752700,"startTime":"0","endTime":"0","summary":"Investor webcast on Monday, January 27, 2025, at 8:00 a.m. ET to present clinical data SOUTH SAN FRANCISCO, Calif., Jan.  24, 2025  (GLOBE NEWSWIRE) -- Akero Therapeutics, Inc. (Nasdaq: AKRO), a clini","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/01/24/3015109/0/en/Akero-Therapeutics-to-Present-Preliminary-Topline-Week-96-Results-from-Phase-2b-SYMMETRY-Study-Investigating-Efruxifermin-in-Patients-with-Compensated-Cirrhosis-F4-Due-to-MASH.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4505","AKRO","BK4123","BK4585","EFX","BK4588"],"gpt_icon":0},{"id":"2504917592","title":"Akero Therapeutics Price Target Maintained With a $50.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2504917592","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2504917592?lang=en_us&edition=fundamental","pubTime":"2025-01-17 00:53","pubTimestamp":1737046380,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/AKRO/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  January 16, 2025 11:53 ET (16:53 GMT)","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["AKRO"],"gpt_icon":0}],"pageSize":16,"totalPage":8,"pageCount":5,"totalSize":113}]}}