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Alnylam Pharmaceuticals

223.27

-9.6800-4.16%

Volume:704.05K

Turnover:162.32M

Market Cap:28.90B

PE:-102.46

High:246.15

Open:246.15

Low:222.57

Close:232.95

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Overview Company News Filings

BUZZ-U.S. STOCKS ON THE MOVE-Cowell, Nike, Alnylam Pharma

Alnylam's Amvuttra Seen as Mega Blockbuster -- Market Talk

Alnylam shares rise on expanded heart drug approval

Alnylam Pharmaceuticals Inc : Wells Fargo Raises Target Price to $287 From $275

THOMSON REUTERS

BUZZ-Alnylam zooms as FDA expands approval of rare heart disease drug

Alnylam Pharmaceuticals Shares up About 7% Premarket After FDA Expands Approval for Drug to Treat Rare Heart Disease

THOMSON REUTERS

Alnylam Pharmaceuticals Inc : Scotiabank Raises Target Price to $338 From $300

THOMSON REUTERS

Alnylam Pharmaceuticals Recieives US FDA Approval for ATTR-CM Drug

MT Newswires Live

Barclays Keeps Their Buy Rating on Alnylam Pharma (ALNY)

U.S. RESEARCH ROUNDUP-Darden Restaurants, Nike, Optinose

Alnylam Pharmaceuticals Inc : RBC Raises Target Price to $330 From $310

THOMSON REUTERS

Alnylam's Amvuttra Gets Approval for Expanded Indication From FDA

Alnylam’s Amvuttra approved by FDA in cardiomyopathy

BRIEF-Alnylam Announces FDA Approval of AMVUTTRA® (vutrisiran)

Alnylam Pharmaceuticals Inc - Majority of Patients Expected to Pay $0 in Out-of-Pocket Costs for Amvuttra

THOMSON REUTERS

Alnylam Pharmaceuticals- Remains on Track to Proceed With Additional Global Regulatory Submissions for Vutrisiran in 2025

THOMSON REUTERS

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The FDA's approval of Alnylam's Amvuttra in the cardiomyopathy of transthyretin-mediated amyloidosis, or ATTR-CM, puts the drug well on track to achieving mega blockbuster status, Citi says. Analysts David Lebowitz and Ike Lee say the drug's label was clean and overall in line with their expectations, which they say will enable strong uptake. The green light makes Amvuttra the only U.S. drug approved to address both cardiomyopathy and polyneuropathy manifestations of ATTR amyloidosis, a factor Citi says could resonate with practitioners. Alnylam up 4.5% premarket to $265. ","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","ALNY","BK4548","BK4588","BK4585"],"gpt_icon":0},{"id":"2521407071","title":"Alnylam shares rise on expanded heart drug approval","url":"https://stock-news.laohu8.com/highlight/detail?id=2521407071","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521407071?lang=en_us&edition=fundamental","pubTime":"2025-03-21 19:32","pubTimestamp":1742556760,"startTime":"0","endTime":"0","summary":"Alnylam shares rise on expanded heart drug approval  March 21 (Reuters) - Alnylam Pharmaceuticals' ALNY.O shares rose about 7% before the bell on Friday following U.S. approval for its drug for a rare","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250321:nL4N3Q40NM:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BBIO","SG9999003800.SGD","LU0289739699.SGD","LU0321505868.SGD","LU0456855351.SGD","LU0170899867.USD","IE00BLSP4239.USD","LU0225771236.USD","LU0058720904.USD","LU0868494617.USD","ALNY","BK4548","BK4599","IE00B19Z3B42.SGD","LU0321505439.SGD","SG9999001176.SGD","IE000M9KFDE8.USD","LU0306806265.USD","LU0122379950.USD","SG9999002224.SGD","BK4592","BK4139","LU1023059063.AUD","LU0234572021.USD","LU1066053197.SGD","SG9999013999.USD","LU0225284248.USD","LU1894683264.USD","LU1057294990.SGD","BK4505","BK4007","IE00BLSP4452.SGD","SGXZ57979304.SGD","SG9999011175.SGD","IE0002270589.USD","BK4533","IE00BBT3K403.USD","LU0985481810.HKD","BK4581","BK4550","SG9999001176.USD","SG9999002232.USD","IE00B19Z3581.USD","BK4568","LU1066051498.USD","BK4588","LU1883839398.USD","LU1894683348.USD","BK4585"],"gpt_icon":1},{"id":"2521186407","title":"Alnylam Pharmaceuticals Inc : Wells Fargo Raises Target Price to $287 From $275","url":"https://stock-news.laohu8.com/highlight/detail?id=2521186407","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521186407?lang=en_us&edition=fundamental","pubTime":"2025-03-21 19:29","pubTimestamp":1742556580,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250321:nFWN3Q40W0:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ALNY","BK4548","BK4588","BK4585"],"gpt_icon":0},{"id":"2521047604","title":"BUZZ-Alnylam zooms as FDA expands approval of rare heart disease drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2521047604","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521047604?lang=en_us&edition=fundamental","pubTime":"2025-03-21 19:06","pubTimestamp":1742555189,"startTime":"0","endTime":"0","summary":"BUZZ-Alnylam zooms as FDA expands approval of rare heart disease drug** Shares of drug developer Alnylam Pharmaceuticals ALNY.O rise 6.5% to $270 premarket** On Thursday, US FDA approved ALNY's injectable drug, Amvuttra, to treat transthyretin amyloid cardiomyopathy , a rare and deadly heart disease** Amvuttra was first approved in 2022 to treat nerve damage related to ATTR-CM** Amvuttra is the first treatment to address both nerve and heart forms of ATTR-CM, working by reducing production of the disease-causing protein** List price of Amvuttra is $119,351 per prefilled syringe, administered every 3 months, with no planned change for ATTR-CM treatment** Brokerage Jefferies said it expects Amvuttra's price to decrease over time as prescription volumes rise, with initial impacts likely in the H2 of this year** ALNY gained 71.4%, in the last 12 months  ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250321:nL4N3Q40TA:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","ALNY","BK4548","BK4588","BK4585"],"gpt_icon":0},{"id":"2521404424","title":"Alnylam Pharmaceuticals Shares up About 7% Premarket After FDA Expands Approval for Drug to Treat Rare Heart Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2521404424","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521404424?lang=en_us&edition=fundamental","pubTime":"2025-03-21 19:04","pubTimestamp":1742555058,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250321:nFWN3Q31DQ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ALNY","BK4548","BK4588","BK4585"],"gpt_icon":0},{"id":"2521401614","title":"Alnylam Pharmaceuticals Inc : Scotiabank Raises Target Price to $338 From $300","url":"https://stock-news.laohu8.com/highlight/detail?id=2521401614","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521401614?lang=en_us&edition=fundamental","pubTime":"2025-03-21 18:46","pubTimestamp":1742553999,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250321:nFWN3Q40LA:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ALNY","BK4548","BK4588","BK4585"],"gpt_icon":0},{"id":"2521427079","title":"Alnylam Pharmaceuticals Recieives US FDA Approval for ATTR-CM Drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2521427079","media":"MT Newswires Live","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521427079?lang=en_us&edition=fundamental","pubTime":"2025-03-21 15:58","pubTimestamp":1742543897,"startTime":"0","endTime":"0","summary":"Alnylam Pharmaceuticals  said late Thursday that the US Food and Drug Administration has approved the supplemental new drug application for its drug Amvuttra for the treatment of cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis  in adults.The approval of the drug, also known as vutrisiran, is meant to reduce cardiovascular mortality, cardiovascular hospitalizations, and urgent heart failure visits, the company said.ATTR-CM is a rapidly progressive and ultimately heart disease without a cure.The approval is based on a phase 3 clinical trial in which Amvuttra showed statistically significant improvement compared with a placebo in all of its 10 pre-specified primary and secondary endpoints, reducing mortality by 36% over 42 months, the company said.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4207","CM","BK4139","ALNY","BK4548","BK4588","BK4585"],"gpt_icon":0},{"id":"2521422224","title":"Barclays Keeps Their Buy Rating on Alnylam Pharma (ALNY)","url":"https://stock-news.laohu8.com/highlight/detail?id=2521422224","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521422224?lang=en_us&edition=fundamental","pubTime":"2025-03-21 15:36","pubTimestamp":1742542565,"startTime":"0","endTime":"0","summary":"Barclays analyst Gena Wang maintained a Buy rating on Alnylam Pharma (ALNY – Research Report) today and set a price target of $329.00. The company’...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/barclays-keeps-their-buy-rating-on-alnylam-pharma-alny-3?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/barclays-keeps-their-buy-rating-on-alnylam-pharma-alny-3?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["ALNY"],"gpt_icon":0},{"id":"2521424845","title":"U.S. RESEARCH ROUNDUP-Darden Restaurants, Nike, Optinose","url":"https://stock-news.laohu8.com/highlight/detail?id=2521424845","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521424845?lang=en_us&edition=fundamental","pubTime":"2025-03-21 15:17","pubTimestamp":1742541448,"startTime":"0","endTime":"0","summary":"U.S. RESEARCH ROUNDUP-Darden Restaurants, Nike, Optinose March 21 (Reuters) - Wall Street securities analysts revised their ratings and price targets on several U.S.-listed companies, including Darden","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250321:nL4N3Q40HD:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0128525689.USD","BK4561","LU1303367103.USD","BK4543","SG9999014039.USD","NKE","KTOS","LU0889566641.SGD","IE0002270589.USD","JBL","LU0792757196.USD","AJG","LU1852331112.SGD","DYN","LU0251131958.USD","SG9999014880.SGD","IE00B19Z3581.USD","BK4588","LU0786609619.USD","LU0081259029.USD","BK4512","BK4505","RWAY","LU0154245673.USD","LU0251142724.SGD","ASO","BK4209","BK4532","LU1861220033.SGD","LU0157215616.USD","OPTN","BK4539","BK4007","BK4603","IE00B3PB1722.GBP","BK4605","FDX","DRI","BK4533","VSTM","LU0082616367.USD","PLMR","GLUE","LU0823411888.USD","ALNY","BK4135","ELEV","BK4107","LU2048586759.USD"],"gpt_icon":1},{"id":"2521774440","title":"Alnylam Pharmaceuticals Inc : RBC Raises Target Price to $330 From $310","url":"https://stock-news.laohu8.com/highlight/detail?id=2521774440","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521774440?lang=en_us&edition=fundamental","pubTime":"2025-03-21 13:29","pubTimestamp":1742534994,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250321:nFWN3Q408C:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","ALNY","BK4548","BK4588","BK4585"],"gpt_icon":0},{"id":"2521841880","title":"Alnylam's Amvuttra Gets Approval for Expanded Indication From FDA","url":"https://stock-news.laohu8.com/highlight/detail?id=2521841880","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2521841880?lang=en_us&edition=fundamental","pubTime":"2025-03-21 06:47","pubTimestamp":1742510820,"startTime":"0","endTime":"0","summary":"Alnylam Pharmaceuticals' amyloidosis drug Amvuttra received Food and Drug Administration approval for an expanded indication.The drug was approved for treatment of the cardiomyopathy of wild-type or hereditary transthyretin-mediated amyloidosis in adults to reduce cardiovascular mortality, cardiovascular hospitalizations and urgent heart-failure visits.Cantor Fitzgerald wrote that \"The most important thing is that it's approved with a broad label: by this, we mean mortality language is in fact included on the front page\" and that the language about urgent heart failure visits is a differentiator compared with other products.Amvuttra was previously approved 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