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(NYSE:CRL)?","url":"https://stock-news.laohu8.com/highlight/detail?id=2494675848","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2494675848?lang=en_us&edition=fundamental","pubTime":"2024-12-27 00:31","pubTimestamp":1735230660,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International (NYSE:CRL) has had a rough three months with its share price down 6.1%. But if...","market":"nz","thumbnail":"https://images.simplywall.st/asset/industry/9551728-choice2-main-header/1585186774276","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/9551728-choice2-main-header/1585186774276"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nyse-crl/charles-river-laboratories-international/news/declining-stock-and-solid-fundamentals-is-the-market-wrong-a-1448","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4121","BK4585","BK4588","LU0390134368.USD","NYSE","CRL","BK4530"],"gpt_icon":0},{"id":"2493711600","title":"Charles River Laboratories International Inc. Stock Outperforms Competitors Despite Losses On The Day","url":"https://stock-news.laohu8.com/highlight/detail?id=2493711600","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493711600?lang=en_us&edition=fundamental","pubTime":"2024-12-24 06:26","pubTimestamp":1734992760,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  slipped 0.20% to $185.39 Monday, on what proved to be an all-around positive trading session for the stock market, with the S&P 500 Index  rising 0.73% to 5,974.07 and the Dow Jones Industrial Average  rising 0.16% to 42,906.95.Charles River Laboratories International Inc. closed $89.61 below its 52-week high , which the company reached on March 8th.Despite its losses, the stock outperformed some of its competitors Monday, as Labcorp Holdings Inc.  fell 0.34% to $227.84 and Alnylam Pharmaceuticals Inc.  fell 1.30% to $242.26.Trading volume  remained 181,168 below its 50-day average volume of 701,289.Data source: Dow Jones Market Data, FactSet. Data compiled December 23, 2024.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published independently from Dow Jones Newswires and The Wall Street ","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2493670230","title":"Year-end selling is hitting these 7 stocks. How their tax loss can be your gain.","url":"https://stock-news.laohu8.com/highlight/detail?id=2493670230","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493670230?lang=en_us&edition=fundamental","pubTime":"2024-12-21 21:27","pubTimestamp":1734787620,"startTime":"0","endTime":"0","summary":"Foot Locker, CVS Health and Charles River Laboratories are among hard-hit stocks that look ready to recover. Hard-core investors hunt for stock-market castoffs every holiday season. Specifically,  they look for stocks that fell so much during the year, they get hit by waves of tax-loss selling from investors wanting to offset capital gains.This \"tax loss selling\" turns banged-up stocks into bargains. To round up names, I recently checked in with four money managers. Stock candidates needed just two qualifications. The stocks had to be down a lot this year - to trigger the tax-loss selling. And the money managers had to be able to make the case that these shares had a good chance to rebound over the next year or two.Nike's move did not work out well, so now it's partnering with retailers again, including Foot Locker. Nike realized \"they need retail partners to reach people who do not buy online,\" Allspring Special Mid Cap Value fund WFMIX portfolio manager Bryant VanCronkhite said in a ","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BSNM7G36.USD","BK4533","LU0070302665.USD","LU0208291251.USD","VAL","IE00BZ1G4Q59.USD","BK4121","BK4585","LU0786609619.USD","LU2098885051.SGD","LU1303367103.USD","BK4020","CRL","SDRL","IE00BKVL7J92.USD","IFSPF","LU0006061336.USD","BK4094","BK4530","LU0211331839.USD","BK4092","FL","LU0162691827.USD","LU1059921491.USD","BK4504","LU0390134368.USD","BK4581","LU1571399168.USD","LU1699723380.USD","LU0823411888.USD","AVNW","BK4561","BK4186","DLHC","BK4550","BK4566","BK4534","BK4130","LU0061475181.USD","NKE","BK4146","LU0072461881.USD","CVS","LU0320765489.SGD","BK4196","BK4558","BIRK","BK4588"],"gpt_icon":1},{"id":"2493408583","title":"Penny Stock Applied Therapeutics' FDA Troubles Trigger Investor Lawsuit, Shareholders Claim Deception Over Govorestat Clinical Data","url":"https://stock-news.laohu8.com/highlight/detail?id=2493408583","media":"Benzinga","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493408583?lang=en_us&edition=fundamental","pubTime":"2024-12-21 06:15","pubTimestamp":1734732951,"startTime":"0","endTime":"0","summary":"Adrian Alexandru, representing all similarly affected investors, has filed a federal securities class-action lawsuit against Applied Therapeutics , alleging the company violated federal securities laws.The lawsuit claims that the company provided misleading information about its clinical trials and failed to disclose key adverse facts, causing significant financial losses for shareholders.Also Read: Rare Disease-Focused Applied Therapeutics' Lead Candidate Govorestat Has Blockbuster Potential, Analyst Sees 140% Stock Upside. The class action covers investors who purchased Applied Therapeutics securities between January 3, 2024, and December 2, 2024.Central to the lawsuit are claims that the company touted positive results from its Phase 3 INSPIRE trial for govorestat for Galactosemia, without disclosing significant issues. Bloomberg Law published a copy of the lawsuit online.Allegations include problems with electronic data capture and dosing errors during the dose-escalation phase of ","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/UajFcVXyBbGW._8YHZnAzA--~B/aD01NTM7dz05ODM7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/Benzinga/d3cae5694e766314b62be2ea5ce66552","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/UajFcVXyBbGW._8YHZnAzA--~B/aD01NTM7dz05ODM7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/Benzinga/d3cae5694e766314b62be2ea5ce66552"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/penny-stock-applied-therapeutics-fda-221551580.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0390134368.USD","BK4585","BK4121","LU0320765992.SGD","CRL","BK4588","LU0889565916.HKD","LENZ","APLT","BK4139","BK4530","LU0109394709.USD"],"gpt_icon":1},{"id":"2493474710","title":"Lexicon receives CRL for Zynquista","url":"https://stock-news.laohu8.com/highlight/detail?id=2493474710","media":"TIPRANKS","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493474710?lang=en_us&edition=fundamental","pubTime":"2024-12-21 05:35","pubTimestamp":1734730553,"startTime":"0","endTime":"0","summary":"Lexicon (LXRX) Pharmaceuticals announced it has received a complete response letter from the U.S. Food and Drug Administration regarding the New Dr...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/lexicon-receives-crl-for-zynquista?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/lexicon-receives-crl-for-zynquista?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4121","CRL","LXRX","BK4585","BK4530","LU0390134368.USD","BK4588"],"gpt_icon":0},{"id":"2493474605","title":"Lexicon Announces Receipt of Complete Response Letter for Zynquista™ (sotagliflozin)","url":"https://stock-news.laohu8.com/highlight/detail?id=2493474605","media":"GlobeNewswire","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493474605?lang=en_us&edition=fundamental","pubTime":"2024-12-21 05:30","pubTimestamp":1734730200,"startTime":"0","endTime":"0","summary":"Confirms Previously Disclosed and Anticipated FDA DecisionTHE WOODLANDS, Texas, Dec.  20, 2024  (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced it has received a compl","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/12/20/3000869/0/en/Lexicon-Announces-Receipt-of-Complete-Response-Letter-for-Zynquista-sotagliflozin.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL","BK4530","BK4121","BK4585","BK4007","HCM","LU0390134368.USD","BK4588","BK4531"],"gpt_icon":0},{"id":"2492410649","title":"Tax-related selling is hitting these 7 stocks - but their loss could be your gain","url":"https://stock-news.laohu8.com/highlight/detail?id=2492410649","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492410649?lang=en_us&edition=fundamental","pubTime":"2024-12-20 20:51","pubTimestamp":1734699060,"startTime":"0","endTime":"0","summary":"Foot Locker, CVS Health and Charles River Laboratories are among hard-hit stocks that look ready to recover. Hard-core investors hunt for stock-market castoffs every holiday season. Specifically,  they look for stocks that fell so much during the year, they get hit by waves of tax-loss selling from investors wanting to offset capital gains.This \"tax loss selling\" turns banged-up stocks into bargains. To round up names, I recently checked in with four money managers. Stock candidates needed just two qualifications. The stocks had to be down a lot this year - to trigger the tax-loss selling. And the money managers had to be able to make the case that these shares had a good chance to rebound over the next year or two.","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4121","CVS","LU0006061336.USD","IE00BKVL7J92.USD","DLHC","BK4094","LU0162691827.USD","BK4092","BK4534","BK4196","AVNW","BK4533","LU1571399168.USD","LU1303367103.USD","VAL","BK4186","LU1699723380.USD","BK4588","IE00BSNM7G36.USD","IFSPF","IE00BZ1G4Q59.USD","BK4130","FL","BK4020","LU0070302665.USD","BIRK","LU0061475181.USD","NKE","LU0211331839.USD","BK4146","BK4566","LU0208291251.USD","LU0786609619.USD","BK4558","BK4504","LU0072461881.USD","LU2098885051.SGD","LU0823411888.USD","LU1059921491.USD","BK4581","LU0320765489.SGD","BK4561","SDRL","CRL","BK4530","LU0390134368.USD","BK4585","BK4550"],"gpt_icon":1},{"id":"2492438315","title":"Charles River Laboratories International Inc. Stock Underperforms Thursday When Compared To Competitors","url":"https://stock-news.laohu8.com/highlight/detail?id=2492438315","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492438315?lang=en_us&edition=fundamental","pubTime":"2024-12-20 06:26","pubTimestamp":1734647160,"startTime":"0","endTime":"0","summary":"This article was automatically generated by MarketWatch using technology from Automated Insights.Shares of Charles River Laboratories International Inc.  slipped 0.55% to $182.15 Thursday, on what proved to be an all-around mixed trading session for the stock market, with the Dow Jones Industrial Average  rising 0.04% to 42,342.24 and the S&P 500 Index  falling 0.09% to 5,867.08.This was the stock's fifth consecutive day of losses.Charles River Laboratories International Inc. closed $92.85 below its 52-week high , which the company reached on March 8th.The stock underperformed when compared to some of its competitors Thursday, as Labcorp Holdings Inc.  rose 0.29% to $226.97 and Alnylam Pharmaceuticals Inc.  rose 0.40% to $238.87.Trading volume  remained 81,626 below its 50-day average volume of 693,056.Data source: Dow Jones Market Data, FactSet. Data compiled December 19, 2024.This content was created by MarketWatch, which is operated by Dow Jones & Co. MarketWatch is published indepe","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CRL"],"gpt_icon":0},{"id":"2492948523","title":"Zealand Pharma says FDA issues CRL for glepaglutide NDA","url":"https://stock-news.laohu8.com/highlight/detail?id=2492948523","media":"TIPRANKS","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492948523?lang=en_us&edition=fundamental","pubTime":"2024-12-20 04:05","pubTimestamp":1734638724,"startTime":"0","endTime":"0","summary":"Zealand Pharma (ZLDPF) announced that the U.S. Food and Drug Administration has issued a Complete Response Letter for the company’s New Drug Applic...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/zealand-pharma-says-fda-issues-crl-for-glepaglutide-nda?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/zealand-pharma-says-fda-issues-crl-for-glepaglutide-nda?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["CRL","ZLDPF","BK4530","BK4585","BK4588","LU0390134368.USD","BK4121","BK4139"],"gpt_icon":0},{"id":"2492489920","title":"U.S. Food and Drug Administration issues Complete Response Letter for the glepaglutide New Drug Application for the treatment of short bowel syndrome","url":"https://stock-news.laohu8.com/highlight/detail?id=2492489920","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492489920?lang=en_us&edition=fundamental","pubTime":"2024-12-20 03:58","pubTimestamp":1734638280,"startTime":"0","endTime":"0","summary":"U.S. Food and Drug Administration issues Complete Response Letter for the glepaglutide New Drug Application for the treatment of short bowel syndrome. The FDA concluded that Zealand Pharma’s application did not meet the full requirements for substantial evidence to establish the efficacy and safety of the to-be-marketed dose of glepaglutide.Zealand Pharma will continue the dialogue with the FDA to align on the path toward obtaining regulatory approval in the U.S.Zealand Pharma expects to proceed with its current plans for a European Marketing Authorization Application submission in 2025.Copenhagen, Denmark, December 19, 2024 – Zealand Pharma A/S   , a biotechnology company focused on the discovery and development of innovative peptide-based medicines, today announced that the U.S. Food and Drug Administration  has issued a Complete Response Letter  for the company’s New Drug Application  for glepaglutide, a long-acting GLP-2 analog, under development for the treatment of adult patients","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/cgyYMo5QPKpW7CjArtwXjQ--~B/aD0yNDQ7dz02MDY7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/globenewswire.com/76be332007740327e38ca6218ee6aa06","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/cgyYMo5QPKpW7CjArtwXjQ--~B/aD0yNDQ7dz02MDY7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/globenewswire.com/76be332007740327e38ca6218ee6aa06"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/u-food-drug-administration-issues-195800394.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CRL","ZLDPF","SBS","BK4588","BK4139","BK4121","BK4172","BK4530","LU0390134368.USD","BK4585"],"gpt_icon":0},{"id":"2492174294","title":"Earnings are growing at Charles River Laboratories International (NYSE:CRL) but shareholders still don't like its prospects","url":"https://stock-news.laohu8.com/highlight/detail?id=2492174294","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492174294?lang=en_us&edition=fundamental","pubTime":"2024-12-19 22:34","pubTimestamp":1734618885,"startTime":"0","endTime":"0","summary":"Investing in stocks inevitably means buying into some companies that perform poorly. But the last three years have been particularly tough on longer term Charles River Laboratories International, Inc.  shareholders. Unfortunately, they have held through a 50% decline in the share price in that time. And over the last year the share price fell 21%, so we doubt many shareholders are delighted. Furthermore, it's down 13% in about a quarter. That's not much fun for holders.After losing 5.4% this past week, it's worth investigating the company's fundamentals to see what we can infer from past performance.While the broader market gained around 26% in the last year, Charles River Laboratories International shareholders lost 21%. However, keep in mind that even the best stocks will sometimes underperform the market over a twelve month period. Longer term investors wouldn't be so upset, since they would have made 4%, each year, over five years. If the fundamental data continues to indicate long","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/dC75hPkPk1wNzUHQ29Af1A--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/2319011507a24b47a4bb11db126344d3","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/dC75hPkPk1wNzUHQ29Af1A--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/2319011507a24b47a4bb11db126344d3"],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/earnings-growing-charles-river-laboratories-143445589.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["NYSE","CRL"],"gpt_icon":0},{"id":"2492418013","title":"Deutsche Bank Adjusts Charles River Laboratories International Price Target to $245 From $250","url":"https://stock-news.laohu8.com/highlight/detail?id=2492418013","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492418013?lang=en_us&edition=fundamental","pubTime":"2024-12-18 23:42","pubTimestamp":1734536565,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International (CRL) has an average rating of Hold and mean price target of $210.63, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and econom","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["CRL","DB"],"gpt_icon":0},{"id":"2492961008","title":"FDA Gives CRL to J&J's BLA for Subcutaneous Rybrevant in NSCLC","url":"https://stock-news.laohu8.com/highlight/detail?id=2492961008","media":"Zacks","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492961008?lang=en_us&edition=fundamental","pubTime":"2024-12-17 21:21","pubTimestamp":1734441660,"startTime":"0","endTime":"0","summary":"Johnson & Johnson JNJ announced that the FDA has issued a complete response letter  to its biologics license application  seeking approval for the subcutaneous  formulation of its EGFR/MET inhibitor, Rybrevant, for EGFR-mutated non-small cell lung cancer .Rybrevant is currently approved as an intravenous  formulation as a combination therapy for treating NSCLC across different lines of treatment and various mutations.The BLA is seeking approval for a fixed combination of SC Rybrevant and recombinant human hyaluronidase for treating patients with EGFR-mutated NSCLC. The BLA was based on data from the phase III PALOMA-3 study and was granted Priority Review by the FDA in August.The CRL was issued as part of the FDA’s standard pre-approval inspection at a manufacturing facility.Per J&J, the CRL is not related to the product formulation or the efficacy and safety data submitted in the regulatory application. The regulatory body has not requested for any additional clinical studies to be 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Stanley Trims Price Target on Charles River Laboratories International to $220 From $225, Keeps Equalweight Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2492595769","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492595769?lang=en_us&edition=fundamental","pubTime":"2024-12-17 20:30","pubTimestamp":1734438642,"startTime":"0","endTime":"0","summary":"Charles River Laboratories International (CRL) has an average rating of hold and mean price target of $210.94, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and 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Rejection","url":"https://stock-news.laohu8.com/highlight/detail?id=2491658692","media":"Benzinga","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491658692?lang=en_us&edition=fundamental","pubTime":"2024-12-16 22:22","pubTimestamp":1734358921,"startTime":"0","endTime":"0","summary":"On Friday, the FDA approved Checkpoint Therapeutics, Inc.’s  Unloxcyt for metastatic cutaneous squamous cell carcinoma  or locally advanced cSCC who are not candidates for curative surgery or curative radiation.Unloxcyt is the first and only programmed death ligand-1  blocking antibody to receive FDA marketing approval for this indication.The recommended commercial dosage of Unloxcyt is 1,200 mg administered as an intravenous infusion over 60 minutes every three weeks.The FDA approval comes ahead of its PDUFA date of December 28.“Today’s FDA approval of Unloxcyt – the first marketing approval for our company...This approval marks Checkpoint’s transformation to a commercial-stage company, with the opportunity to compete in a U.S. market estimated to exceed $1 billion annually, where we believe Unloxcyt offers a differentiated treatment option versus available therapies,” said James Oliviero, President and Chief Executive Officer of Checkpoint.FDA approval for Unloxcyt was granted based 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