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Dyne Therapeutics, Inc.

15.62

-0.5700-3.52%

Pre-market: 15.30-0.3200-2.05%09:21 EST

Volume:1.93M

Turnover:29.97M

Market Cap:2.53B

PE:-4.31

High:16.01

Open:15.72

Low:15.10

Close:16.19

52wk High:25.00

52wk Low:6.36

Shares:162.00M

Float Shares:152.00M

Volume Ratio:0.92

T/O Rate:1.27%

Dividend:- -

Dividend Rate:- -

EPS(TTM):-3.6224

EPS(LYR):-3.3716

ROE:-60.66%

ROA:-34.32%

PB:3.66

PE(LYR):-4.63

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Overview Company News Filings

Dyne Therapeutics reports $791.9 million cash position as of September 30, 2025

Dyne Therapeutics Q3 Basic EPS USD -0.76

THOMSON REUTERS

Dyne Therapeutics Q3 EPS USD -0.76 VS. Ibes Estimate USD -0.84

THOMSON REUTERS

Dyne Therapeutics Inc: Reaffirming Expected Cash Runway Into Q3 2027

THOMSON REUTERS

Dyne Therapeutics Inc : JP Morgan Raises Target Price to $18 From $9

THOMSON REUTERS

Dyne Therapeutics to Present at Evercore Healthcare Conference

This biotech's stock soared as investors look for the next buyout target

Small U.S. Stocks End Mixed As Dyne Therapeutics Leads, Intellia Therapeutics Lags

Dyne Therapeutics Shares Rise After Novartis Reaches Deal to Buy Avidity

BUZZ-U.S. STOCKS ON THE MOVE-PepGen, Turbo Energy, Qualcomm

BUZZ-PepGen, Dyne rise after Novartis' $12 bln deal to buy rival Avidity

Dyne Therapeutics rises 42.4%

Stifel Nicolaus Keeps Their Buy Rating on Dyne Therapeutics (DYN)

Dyne Therapeutics Faces Overhang Ahead of Data Readout, Oppenheimer Says

MT Newswires Live

Dyne Therapeutics, Inc. : Oppenheimer Cuts to Perform From Outperform

THOMSON REUTERS

Dyne Therapeutics downgraded to Perform at Oppenheimer following additional data

Dyne Therapeutics Announces Positive One-Year Phase 1/2 Data for Zeleciment Basivarsen Demonstrating Functional Improvement in Myotonic Dystrophy Type 1

Dyne Therapeutics Announces Additional One-Year Clinical Data Demonstrating Functional Improvement From Phase 1/2 Achieve Trial of Zeleciment Basivarsen (Dyne-101) for Myotonic Dystrophy Type 1 (Dm1)

THOMSON REUTERS

A Fresh Look at Dyne Therapeutics (DYN) Valuation Following Japan Orphan Drug Win and Board Addition

Simply Wall St.

Dyne Therapeutics Elects Brian Posner to Board

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Therapeutics reports $791.9 million cash position as of September 30, 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2581470216","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581470216?lang=en_us&edition=fundamental","pubTime":"2025-11-06 05:27","pubTimestamp":1762378073,"startTime":"0","endTime":"0","summary":"Dyne Therapeutics Inc. reported a net loss of $108.0 million, or $0.76 per basic and diluted share, for the third quarter ended September 30, 2025, compared to a net loss of $97.1 million, or $0.96 per basic and diluted share, for the same period in 2024. Research and development expenses were $97.2 million, up from $92.8 million in the prior year quarter. General and administrative expenses were $16.7 million, compared to $12.9 million a year earlier. As of September 30, 2025, cash, cash equivalents, and marketable securities totaled $791.9 million, with the company expecting these funds to support operations into the third quarter of 2027. Business developments included the company remaining on track to report topline data from the registrational expansion cohort of the DELIVER trial of zeleciment rostudirsen in December 2025, supporting a potential U.S. accelerated approval submission in the second quarter of 2026. The FDA granted Breakthrough Therapy Designation to zeleciment rostu","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251105:nNDL21Ch0f:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4505","DYN","BK4585","BK4588","BK4139"],"gpt_icon":0},{"id":"2581941701","title":"Dyne Therapeutics Q3 Basic EPS USD -0.76","url":"https://stock-news.laohu8.com/highlight/detail?id=2581941701","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581941701?lang=en_us&edition=fundamental","pubTime":"2025-11-06 05:10","pubTimestamp":1762377001,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251105:nPLX5333A1:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","BK4505","BK4588","BK4585","DYN"],"gpt_icon":0},{"id":"2581470194","title":"Dyne Therapeutics Q3 EPS USD -0.76 VS. Ibes Estimate USD -0.84","url":"https://stock-news.laohu8.com/highlight/detail?id=2581470194","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581470194?lang=en_us&edition=fundamental","pubTime":"2025-11-06 05:10","pubTimestamp":1762377001,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251105:nPLX5333A1:5","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4505","BK4139","BK4585","DYN","BK4588"],"gpt_icon":0},{"id":"2581088063","title":"Dyne Therapeutics Inc: Reaffirming Expected Cash Runway Into Q3 2027","url":"https://stock-news.laohu8.com/highlight/detail?id=2581088063","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581088063?lang=en_us&edition=fundamental","pubTime":"2025-11-06 05:10","pubTimestamp":1762377001,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251105:nPLX5333A1:6","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4585","DYN","BK4139","BK4505","BK4588"],"gpt_icon":0},{"id":"2581203897","title":"Dyne Therapeutics Inc : JP Morgan Raises Target Price to $18 From $9","url":"https://stock-news.laohu8.com/highlight/detail?id=2581203897","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581203897?lang=en_us&edition=fundamental","pubTime":"2025-11-05 21:06","pubTimestamp":1762347999,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251105:nFWN3WH26L:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","DYN","BK4585","BK4505","BK4588"],"gpt_icon":0},{"id":"2580290714","title":"Dyne Therapeutics to Present at Evercore Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2580290714","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2580290714?lang=en_us&edition=fundamental","pubTime":"2025-11-03 20:30","pubTimestamp":1762173026,"startTime":"0","endTime":"0","summary":"Dyne Therapeutics Inc., a clinical-stage company focused on genetically driven neuromuscular diseases, will participate in a fireside chat at the 8th Annual Evercore Healthcare Conference on December 2, 2025, in Coral Gables, FL. A live webcast of the presentation will be available on the company's website.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Dyne Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire  on November 03, 2025, and is solely responsible for the information contained therein.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251103:nNDL360rPG:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B64PRP62.GBP","DYN","BK4505","BK4585","LU2210149790.SGD","IE00BGHQF748.EUR","BK4112","IE00BKPKM429.USD","BK4139","LU2210150020.SGD","IE00B3QW5Z07.USD","LU0314104364.USD","NDAQ","LU2095319765.USD","BK4588"],"gpt_icon":0},{"id":"2578676161","title":"This biotech's stock soared as investors look for the next buyout target","url":"https://stock-news.laohu8.com/highlight/detail?id=2578676161","media":"Dow Jones","labels":["merge"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578676161?lang=en_us&edition=fundamental","pubTime":"2025-10-28 04:54","pubTimestamp":1761598440,"startTime":"0","endTime":"0","summary":"A big premium paid to acquire Avidity Biosciences is bolstering the merger case for Dyne Therapeutics, analyst says. Dyne Therapeutics' stock sees record rally, but one analyst says it could still climb a lot further, after a rival got bought out for a big premium.The buyout of one biotechnology company can sometimes hurt the shares of its competitors, as investors may feel like they picked the wrong merger candidate. But not in the case for those who bought into Avidity Biosciences Inc.'s top competitor.Avidity  said over the weekend that it agreed to be acquired by Switzerland-based drug giant Novartis AG  in a $12 billion deal that valued Avidity shares at a 46.5% premium to Friday's closing price.What Novartis wants is access to Avidity's drug-delivery platform for RNA therapeutics, and the company's clinical development programs and pipeline in neuroscience, including those in late-stage trials, such as its treatment for Duchenne muscular dystrophy.And besides, he doesn't believe ","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"merge","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4532","BK4505","BK4585","NVS","IE00BJJMRZ35.SGD","IE00B2B36J28.USD","LU0211331839.USD","BK4588","IE0002141913.USD","DYN","BK4007","IE00B4R5TH58.HKD","LU0070302665.USD","BK4550","IE0009355771.USD","FDN","BK4578","IE00BFTCPJ56.SGD","LU0320765489.SGD","IE00BJT1NW94.SGD","LU0208291251.USD","RNA"],"gpt_icon":0},{"id":"2578673025","title":"Small U.S. Stocks End Mixed As Dyne Therapeutics Leads, Intellia Therapeutics Lags","url":"https://stock-news.laohu8.com/highlight/detail?id=2578673025","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578673025?lang=en_us&edition=fundamental","pubTime":"2025-10-28 04:20","pubTimestamp":1761596400,"startTime":"0","endTime":"0","summary":"This article was automatically generated using Dow Jones technology.Shares of small-cap companies were mixed Monday, as the Russell 2000 Index added 0.3%, while the S&P Small Cap 600 Index was down 0.1%.Among companies with a market value of $1 billion to $6.7 billion, Dyne Therapeutics Inc. was the best performer during the session, surging 41%, followed by Zenas BioPharma Inc., which jumped 33%. Hotel101 Global Holdings Corp. shares surged 20%, Corporacion America Airports S.A. jumped 17%, and shares of Immunovant Inc. jumped 13%.Intellia Therapeutics Inc. was the biggest laggard, dropping 42%, followed by shares of Organon & Co., which dropped 23%. Shares of United States Antimony Corp. dropped 20%, Jyong Biotech Ltd. shares tumbled 18%, and Critical Metals Corp. plunged 14%.Major stock indexes in the U.S. closed up Monday as the Nasdaq Composite Index increased 1.9%. Meanwhile, the S&P 500 Index increased 1.2%, and the Dow Jones Industrial Average increased 0.7%.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1861559042.SGD","BK4535","BK4139","LU1861558580.USD","BK4556","NTLA","DYN","BK4588","BK4505","BK4585"],"gpt_icon":0},{"id":"2578651621","title":"Dyne Therapeutics Shares Rise After Novartis Reaches Deal to Buy Avidity","url":"https://stock-news.laohu8.com/highlight/detail?id=2578651621","media":"Dow Jones","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578651621?lang=en_us&edition=fundamental","pubTime":"2025-10-28 01:22","pubTimestamp":1761585720,"startTime":"0","endTime":"0","summary":"Dyne Therapeutics shares were higher Monday after Avidity Biosciences, a competitor developing drugs for neuromuscular disorders, agreed to be sold to Novartis for $12 billion.Dyne shares rose 41% to $24.14 and are up about 2% this year.Stifel said in a note that it expected Dyne shares to trade \"meaningfully higher\" after the Avidity announcement. It said it considers the Avidity deal \"highly validating for the space.\"","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NVS","BK4505","BK4532","BK4585","LU0320765489.SGD","RNA","BK4139","DYN","IE00BJT1NW94.SGD","IE0002141913.USD","LU0070302665.USD","IE00BJJMRZ35.SGD","IE00BFTCPJ56.SGD","BK4578","IE00B2B36J28.USD","LU0208291251.USD","LU0211331839.USD","BK4588","IE0009355771.USD","IE00B4R5TH58.HKD","BK4007"],"gpt_icon":0},{"id":"2578080626","title":"BUZZ-U.S. STOCKS ON THE MOVE-PepGen, Turbo Energy, Qualcomm","url":"https://stock-news.laohu8.com/highlight/detail?id=2578080626","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578080626?lang=en_us&edition=fundamental","pubTime":"2025-10-28 00:35","pubTimestamp":1761582919,"startTime":"0","endTime":"0","summary":"BUZZ-U.S. STOCKS ON THE MOVE-PepGen, Turbo Energy, QualcommEikon search string for individual stock moves: STXBZThe Day Ahead newsletter: https://refini.tv/3LI4BU7The Morning News Call newsletter: htt","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251027:nL6N3W80QU:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["NEE","NVD3.UK","RVTY","NTLA","NVDD","GE","CRI","NVDS.UK","HL","PLD","SCCO","TURB","NVD","RNA","ADM","CADE","DQ","QCOM","SOHO","WEC","BBIO","ES","OGN","ALB","CDE","RVMD","HON","3NVD.UK","XEL","PPTA","WTRG","KDP","PEPG","NVD2.UK","PRE","SNVD.UK","DYN"],"gpt_icon":1},{"id":"2578236466","title":"BUZZ-PepGen, Dyne rise after Novartis' $12 bln deal to buy rival Avidity","url":"https://stock-news.laohu8.com/highlight/detail?id=2578236466","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578236466?lang=en_us&edition=fundamental","pubTime":"2025-10-27 23:24","pubTimestamp":1761578674,"startTime":"0","endTime":"0","summary":"BUZZ-PepGen, Dyne rise after Novartis' $12 bln deal to buy rival Avidity** Shares of drug developer PepGen PEPG.O up 21% at $5.53, while Dyne Therapeutics DYN.O rise 37.5% at $23.54 ** Rival Avidity Biosciences RNA.O on Sunday agreed to be acquired by Swiss drugmaker Novartis NOVN.S for about $12 billion in cash to bolster its portfolio of treatments for rare muscle disorders ** Pepgen and Dyne are also currently developing drugs to treat rare muscle disorders such as myotonic dystrophy type 1 ** \"We anticipate DYN to trade materially higher tomorrow given similar platform, not materially behind RNA and $2.4b cap\"- RBC Capital Markets ** Including session moves, DYN up 1.8% and PEPG up 47.8% YTD ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251027:nL4N3W81AH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","BK4505","BK4585","BK4139","DYN","PEPG","RNA"],"gpt_icon":0},{"id":"2578647221","title":"Dyne Therapeutics rises 42.4%","url":"https://stock-news.laohu8.com/highlight/detail?id=2578647221","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578647221?lang=en_us&edition=fundamental","pubTime":"2025-10-27 22:05","pubTimestamp":1761573943,"startTime":"0","endTime":"0","summary":"Dyne Therapeutics (DYN) is up 42.4%, or $7.26 to $24.38. Published first on TheFly – the ultimate source for real-time, market-moving breaking fina...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/dyne-therapeutics-rises-42-4-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/dyne-therapeutics-rises-42-4-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4505","BK4585","BK4139","BK4588","DYN"],"gpt_icon":0},{"id":"2578610539","title":"Stifel Nicolaus Keeps Their Buy Rating on Dyne Therapeutics (DYN)","url":"https://stock-news.laohu8.com/highlight/detail?id=2578610539","media":"TIPRANKS","labels":["express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578610539?lang=en_us&edition=fundamental","pubTime":"2025-10-27 18:56","pubTimestamp":1761562569,"startTime":"0","endTime":"0","summary":"Stifel Nicolaus analyst Paul Matteis reiterated a Buy rating on Dyne Therapeutics today and set a price target of $36.00. The company’s shares clos...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/stifel-nicolaus-keeps-their-buy-rating-on-dyne-therapeutics-dyn-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/stifel-nicolaus-keeps-their-buy-rating-on-dyne-therapeutics-dyn-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"express","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["DYN","SF"],"gpt_icon":0},{"id":"2574654108","title":"Dyne Therapeutics Faces Overhang Ahead of Data Readout, Oppenheimer Says","url":"https://stock-news.laohu8.com/highlight/detail?id=2574654108","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2574654108?lang=en_us&edition=fundamental","pubTime":"2025-10-10 23:31","pubTimestamp":1760110300,"startTime":"0","endTime":"0","summary":"Dyne Therapeutics'  new data supported DYNE-101's treatment effect on myotonic dystrophy type 1 patients but a key overhang remains, Oppenheimer said in a note Friday.\"We view powering of the pivotal study  as a key overhang given the small cohort size and statistical variability,\" the report said.Following a recent stock rally, Oppenheimer analysts said they are stepping to the sidelines based on valuation ahead of pivotal readout later this year from DYN-251 in duchenne muscular dystrophy, where they remain \"cautious around safety.\"Oppenheimer downgraded the stock to perform.Shares were down over 4% in recent trading.Price: 14.07, Change: -0.61, Percent Change: -4.16","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["DYN","BK4139","OPY","BK4505","BK4585","BK4588","BK4127"],"gpt_icon":0},{"id":"2574175063","title":"Dyne Therapeutics, Inc. : Oppenheimer Cuts to Perform From Outperform","url":"https://stock-news.laohu8.com/highlight/detail?id=2574175063","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2574175063?lang=en_us&edition=fundamental","pubTime":"2025-10-10 20:19","pubTimestamp":1760098759,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251010:nAZN4NA0N7:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4585","DYN","BK4139","BK4505","BK4588"],"gpt_icon":0},{"id":"2574612220","title":"Dyne Therapeutics downgraded to Perform at Oppenheimer following additional data","url":"https://stock-news.laohu8.com/highlight/detail?id=2574612220","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2574612220?lang=en_us&edition=fundamental","pubTime":"2025-10-10 18:20","pubTimestamp":1760091637,"startTime":"0","endTime":"0","summary":"As previously reported, Oppenheimer downgraded Dyne Therapeutics (DYN) to Perform from Outperform but kept a price target of $13 after the company ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/dyne-therapeutics-downgraded-to-perform-at-oppenheimer-following-additional-data-thefly?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/dyne-therapeutics-downgraded-to-perform-at-oppenheimer-following-additional-data-thefly?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["DYN","OPY"],"gpt_icon":0},{"id":"2573298965","title":"Dyne Therapeutics Announces Positive One-Year Phase 1/2 Data for Zeleciment Basivarsen Demonstrating Functional Improvement in Myotonic Dystrophy Type 1","url":"https://stock-news.laohu8.com/highlight/detail?id=2573298965","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573298965?lang=en_us&edition=fundamental","pubTime":"2025-10-07 06:01","pubTimestamp":1759788074,"startTime":"0","endTime":"0","summary":"Dyne Therapeutics Announces Positive One-Year Phase 1/2 Data for Zeleciment Basivarsen Demonstrating Functional Improvement in Myotonic Dystrophy Type 1. Dyne Therapeutics Inc. announced additional one-year data from its ongoing Phase 1/2 ACHIEVE clinical trial evaluating zeleciment basivarsen  in patients with myotonic dystrophy type 1 . The results demonstrated clinically meaningful improvements in function and strength at the selected registrational dose, with both patients and physicians reporting reductions in overall disease burden. These findings were presented at the 30th Annual International Congress of the World Muscle Society , held virtually and in Vienna, Austria, from October 7-11, 2025. Poster presentations and symposium materials are available on Dyne's website in the Scientific Publications & Presentations section.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely i","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251006:nNDL2VmhZF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","BK4112","DYN","LU0314104364.USD","LU2210149790.SGD","IE00B64PRP62.GBP","BK4585","LU2210150020.SGD","NDAQ","BK4505","BK4588","IE00B3QW5Z07.USD","LU2095319765.USD","IE00BKPKM429.USD","IE00BGHQF748.EUR"],"gpt_icon":0},{"id":"2573989651","title":"Dyne Therapeutics Announces Additional One-Year Clinical Data Demonstrating Functional Improvement From Phase 1/2 Achieve Trial of Zeleciment Basivarsen (Dyne-101) for Myotonic Dystrophy Type 1 (Dm1)","url":"https://stock-news.laohu8.com/highlight/detail?id=2573989651","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573989651?lang=en_us&edition=fundamental","pubTime":"2025-10-07 06:01","pubTimestamp":1759788060,"startTime":"0","endTime":"0","summary":null,"market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251006:nTUA8FNWP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["DYN","BK4139","BK4505","BK4585","BK4588"],"gpt_icon":0},{"id":"2573695628","title":"A Fresh Look at Dyne Therapeutics (DYN) Valuation Following Japan Orphan Drug Win and Board Addition","url":"https://stock-news.laohu8.com/highlight/detail?id=2573695628","media":"Simply Wall St.","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2573695628?lang=en_us&edition=fundamental","pubTime":"2025-10-06 05:15","pubTimestamp":1759698951,"startTime":"0","endTime":"0","summary":"Dyne Therapeutics (DYN) just received Orphan Drug designation in Japan for its experimental drug DYNE-251, following encouraging results from the DELIVER trial. The company also named veteran executive Brian Posner to its board.\nSee our latest analysis for Dyne Therapeutics.\nAfter gaining Orphan Drug status in Japan and welcoming a seasoned leader to its board, Dyne Therapeutics has caught more eyes in the biotech space. While the latest share price sits at $13.06, the 90-day share price...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6111000-choice2-main-header/1585186599552"],"rights":{"source":"simplywall_highlight","url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-dyn/dyne-therapeutics/news/a-fresh-look-at-dyne-therapeutics-dyn-valuation-following-ja","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-dyn/dyne-therapeutics/news/a-fresh-look-at-dyne-therapeutics-dyn-valuation-following-ja","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["BK4588","DYN","BK4505","BK4585","BK4139"],"gpt_icon":0},{"id":"2572523943","title":"Dyne Therapeutics Elects Brian Posner to Board","url":"https://stock-news.laohu8.com/highlight/detail?id=2572523943","media":"TIPRANKS","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2572523943?lang=en_us&edition=fundamental","pubTime":"2025-10-03 04:30","pubTimestamp":1759437052,"startTime":"0","endTime":"0","summary":"An announcement from Dyne Therapeutics ( ($DYN) ) is now available. On October 1, 2025, Dyne Therapeutics, Inc. announced the election of Brian Pos...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/dyne-therapeutics-elects-brian-posner-to-board?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/dyne-therapeutics-elects-brian-posner-to-board?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4505","DYN","BK4588","BK4585","BK4139"],"gpt_icon":0}],"pageSize":20,"totalPage":6,"pageCount":5,"totalSize":111,"code":"91000000","status":"200"}]}}