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Monte Rosa Therapeutics

16.35

+0.33002.06%

Post-market: 16.24-0.1100-0.67%18:38 EDT

Volume:629.88K

Turnover:10.43M

Market Cap:1.25B

PE:64.77

High:16.89

Open:16.59

Low:16.31

Close:16.02

52wk High:25.77

52wk Low:3.50

Shares:76.24M

Float Shares:24.48M

Volume Ratio:0.77

T/O Rate:2.57%

Dividend:- -

Dividend Rate:- -

EPS(TTM):0.2524

EPS(LYR):-0.9836

ROE:9.28%

ROA:1.37%

PB:5.07

PE(LYR):-16.62

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Overview Company News Filings

Monte Rosa Therapeutics Announces Phase 1 Study of NEK7 Degrader MRT-8102 for Cardiovascular Diseases

Monte Rosa Therapeutics presents preclinical data on MRT-8102

Monte Rosa Therapeutics Presents Preclinical Data at AHA Scientific Sessions 2025 on the Potential of MRT-8102, a NEK7-directed Molecular Glue Degrader, to Treat Cardiovascular and Cardiometabolic Diseases

Monte Rosa Therapeutics Is Maintained at Equal-Weight by Wells Fargo

Monte Rosa Therapeutics Reports Strong Revenue Growth

Monte Rosa Therapeutics Inc reports results for the quarter ended September 30 - Earnings Summary

Monte Rosa Therapeutics: Strategic Partnerships and Growth Potential Justify Buy Rating

Monte Rosa Therapeutics Showcases Pipeline Advances and Strategic Partnerships in Protein Degradation Therapies

Monte Rosa Therapeutics Q3 Sales $12.768M Beat $5.420M Estimate

Monte Rosa Q3 net loss widens, but revenue increases on Novartis payment

BRIEF-Monte Rosa Therapeutics Q3 Operating Income USD -32.975 Million

Press Release: Monte Rosa Therapeutics Announces Third Quarter 2025 Financial Results and Business Updates

Monte Rosa Therapeutics Inc expected to post a loss of 37 cents a share - Earnings Preview

Monte Rosa Therapeutics to Present at Piper Sandler 37th Annual Healthcare Conference

Monte Rosa Therapeutics to Participate in Upcoming Investor Conferences

Monte Rosa Therapeutics Advances with MRT-8102: A Promising Phase 1 Study

Guggenheim Sticks to Their Buy Rating for Monte Rosa Therapeutics (GLUE)

Monte Rosa Therapeutics Unveils Preclinical Data on MRT-6160 for Autoimmune Diseases

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Rosa Therapeutics Announces Phase 1 Study of NEK7 Degrader MRT-8102 for Cardiovascular Diseases","url":"https://stock-news.laohu8.com/highlight/detail?id=2582810889","media":"Reuters","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2582810889?lang=en_us&edition=fundamental","pubTime":"2025-11-10 10:08","pubTimestamp":1762740521,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics Inc. announced that it will present preclinical data on MRT-8102, a NEK7-directed molecular glue degrader, at the American Heart Association's Scientific Sessions 2025 in New Orleans. MRT-8102 is being developed as a potential treatment for inflammatory diseases driven by the NLRP3 inflammasome, including cardiovascular and cardiometabolic diseases such as pericarditis and atherosclerosis. The company reported that MRT-8102 selectively degrades NEK7, leading to inhibition of the NLRP3 inflammasome and reduced production of multiple inflammatory cytokines in both in vitro and in vivo models. Initial data from an ongoing Phase 1 study of MRT-8102 in healthy volunteers and subjects with elevated cardiovascular disease risk are expected in the first half of 2026. The preclinical findings will be presented in a poster session on November 8, 2025.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strive","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251110:nNDL1QvLpm:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","NDAQ","LU2095319765.USD","BK4112","LU0314104364.USD","BK4139","LU2210149790.SGD","BK4588","BK4585","IE00BKPKM429.USD","IE00BGHQF748.EUR","LU2210150020.SGD","IE00B64PRP62.GBP","GLUE","IE00B3QW5Z07.USD"],"gpt_icon":0},{"id":"2582981805","title":"Monte Rosa Therapeutics presents preclinical data on 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Rosa Therapeutics Reports Strong Revenue Growth","url":"https://stock-news.laohu8.com/highlight/detail?id=2581020509","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581020509?lang=en_us&edition=fundamental","pubTime":"2025-11-07 13:27","pubTimestamp":1762493231,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics, Inc. ( ($GLUE) ) has released its Q3 earnings. Here is a breakdown of the information Monte Rosa Therapeutics, Inc. presen...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/monte-rosa-therapeutics-reports-strong-revenue-growth?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/monte-rosa-therapeutics-reports-strong-revenue-growth?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["GLUE"],"gpt_icon":0},{"id":"2581014747","title":"Monte Rosa Therapeutics Inc reports results for the quarter ended September 30 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2581014747","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581014747?lang=en_us&edition=fundamental","pubTime":"2025-11-07 04:30","pubTimestamp":1762461007,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics Inc reports results for the quarter ended September 30 - Earnings SummaryMonte Rosa Therapeutics Inc GLUE.OQ reported a quarterly adjusted loss of 33 cents per share for the qu","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251106:nL8N3WI3KO:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","GLUE","BK4539"],"gpt_icon":0},{"id":"2581011007","title":"Monte Rosa Therapeutics: Strategic Partnerships and Growth Potential Justify Buy Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2581011007","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581011007?lang=en_us&edition=fundamental","pubTime":"2025-11-07 03:15","pubTimestamp":1762456526,"startTime":"0","endTime":"0","summary":"LifeSci Capital analyst Oliver McCammon has maintained their bullish stance on GLUE stock, giving a Buy rating on October 23. Oliver McCammon has g...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/monte-rosa-therapeutics-strategic-partnerships-and-growth-potential-justify-buy-rating-ratings?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/monte-rosa-therapeutics-strategic-partnerships-and-growth-potential-justify-buy-rating-ratings?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["GLUE"],"gpt_icon":0},{"id":"2581906090","title":"Monte Rosa Therapeutics Showcases Pipeline Advances and Strategic Partnerships in Protein Degradation Therapies","url":"https://stock-news.laohu8.com/highlight/detail?id=2581906090","media":"Reuters","labels":["corporation"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581906090?lang=en_us&edition=fundamental","pubTime":"2025-11-06 20:33","pubTimestamp":1762432432,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics Inc. has presented updates on its pipeline and strategic collaborations. The company highlighted progress in its wholly owned pipeline, with multiple programs approaching Phase 2 trials in 2026 and additional investigational new drug  applications anticipated over the next two years. Monte Rosa is advancing three clinical programs targeting high medical need indications, leveraging its expertise in molecular glue degraders  and AI-driven protein-protein interaction prediction. Recent collaborations include an agreement with Novartis, under which Monte Rosa received a $150 million upfront payment and is eligible for up to $2.1 billion in milestones, along with a 30% share of U.S. profits and ex-U.S. royalties. Another partnership with Roche grants Roche the right to further develop compounds targeting cancer and neurological diseases. Monte Rosa's technology platform, QuEEN, supports the discovery and rational design of novel MGDs with high selectivity and oral d","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251106:nNDL51FSm2:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"corporation","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["GLUE","BK4539","BK4139"],"gpt_icon":0},{"id":"2581677280","title":"Monte Rosa Therapeutics Q3 Sales $12.768M Beat $5.420M Estimate","url":"https://stock-news.laohu8.com/highlight/detail?id=2581677280","media":"Benzinga","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581677280?lang=en_us&edition=fundamental","pubTime":"2025-11-06 20:24","pubTimestamp":1762431847,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics (NASDAQ:GLUE) reported quarterly sales of $12.768 million which beat the analyst consensus estimate of $5.420 million by 135.57 percent.  This is a 38.54 percent increase over sales of $9.216","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.benzinga.com/news/earnings/25/11/48682830/monte-rosa-therapeutics-q3-sales-12-768m-beat-5-420m-estimate","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["GLUE"],"gpt_icon":0},{"id":"2581067282","title":"Monte Rosa Q3 net loss widens, but revenue increases on Novartis payment","url":"https://stock-news.laohu8.com/highlight/detail?id=2581067282","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581067282?lang=en_us&edition=fundamental","pubTime":"2025-11-06 20:20","pubTimestamp":1762431618,"startTime":"0","endTime":"0","summary":"Monte Rosa Q3 net loss widens, but revenue increases on Novartis paymentOverviewMonte Rosa Q3 net loss widens to $27.1 mln, driven by increased R&D expensesCollaboration revenue for Q3 rises to $12.8 ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251106:nL1N3WI0KC:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","GLUE","BK4139"],"gpt_icon":0},{"id":"2581062236","title":"BRIEF-Monte Rosa Therapeutics Q3 Operating Income USD -32.975 Million","url":"https://stock-news.laohu8.com/highlight/detail?id=2581062236","media":"Reuters","labels":["dataReport","express"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581062236?lang=en_us&edition=fundamental","pubTime":"2025-11-06 20:00","pubTimestamp":1762430457,"startTime":"0","endTime":"0","summary":"BRIEF-Monte Rosa Therapeutics Q3 Operating Income USD -32.975 Million\n\n\nNov 06 (Reuters) - Monte Rosa Therapeutics Q3 collaboration revenue USD 12.768 million.\n\nQ3 net income USD -27.081 million\nQ3 operating expenses USD 45.743 million","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251106:nPLXD56B45:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,express","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4539","BK4139","GLUE"],"gpt_icon":0},{"id":"2581062810","title":"Press Release: Monte Rosa Therapeutics Announces Third Quarter 2025 Financial Results and Business Updates","url":"https://stock-news.laohu8.com/highlight/detail?id=2581062810","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2581062810?lang=en_us&edition=fundamental","pubTime":"2025-11-06 20:00","pubTimestamp":1762430400,"startTime":"0","endTime":"0","summary":"Second agreement signed with Novartis to develop novel degraders for immune-mediated diseases, providing upfront payment of $120 million plus option maintenance payments, and eligibility for option exercise payments, milestones, and tiered royalties. Phase 1 study of NEK7-directed MGD MRT-8102 underway, investigating a potential novel approach to treat inflammatory diseases driven by the NLRP3 inflammasome; initial readout including data from high-CVD risk cohort on track for H1 2026. VAV1-directed MGD MRT-6160 advancing toward anticipated initiation of multiple Phase 2 studies in immune-mediated diseases. \"In regard to our clinical programs, we are enrolling our Phase 1 study of MRT-8102, the only clinical-stage degrader targeting NEK7, which we believe offers a highly differentiated approach to potentially address a wide range of inflammatory and cardio-immunology indications driven by the NLRP3 inflammasome, IL-1<BETA> and IL-6. We have recently initiated dosing a cohort of subjects","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4203","BK4588","BK4099","BK4139","BK4585","TM","BK4604","GLUE","03160","BK4555","HR","BK4225","BK4539"],"gpt_icon":0},{"id":"2580214141","title":"Monte Rosa Therapeutics Inc  expected to post a loss of 37 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2580214141","media":"Reuters","labels":["dataReport","preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2580214141?lang=en_us&edition=fundamental","pubTime":"2025-11-03 22:49","pubTimestamp":1762181385,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics Inc  expected to post a loss of37cents a share - Earnings Preview Monte Rosa Therapeutics Inc GLUE.OQ GLUE.O is expected to  show a fall in quarterly revenue when it reports  r","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251103:nL8N3WF1FU:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport,preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["GLUE","BK4139","BK4539"],"gpt_icon":0},{"id":"2580370297","title":"Monte Rosa Therapeutics to Present at Piper Sandler 37th Annual Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2580370297","media":"Reuters","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2580370297?lang=en_us&edition=fundamental","pubTime":"2025-11-03 20:00","pubTimestamp":1762171234,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics Inc. will participate in the Piper Sandler 37th Annual Healthcare Conference in New York, NY, on December 2, 2025, at 1:30 p.m. ET. Chief Executive Officer Markus Warmuth, MD, will take part in a fireside chat, with a webcast available on the company's website.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligence. While PUBT strives to provide accurate and timely information, this AI-generated content is for informational purposes only and should not be interpreted as financial, investment, or legal advice. Monte Rosa Therapeutics Inc. published the original content used to generate this news brief via GlobeNewswire  on November 03, 2025, and is solely responsible for the information contained therein.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251103:nNDL6xDCKN:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4112","LU2210149790.SGD","IE00B3QW5Z07.USD","BK4588","GLUE","IE00BKPKM429.USD","LU0314104364.USD","LU2095319765.USD","LU2210150020.SGD","BK4585","BK4539","NDAQ","IE00BGHQF748.EUR","BK4139","IE00B64PRP62.GBP"],"gpt_icon":0},{"id":"2580297967","title":"Monte Rosa Therapeutics to Participate in Upcoming Investor Conferences","url":"https://stock-news.laohu8.com/highlight/detail?id=2580297967","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2580297967?lang=en_us&edition=fundamental","pubTime":"2025-11-03 20:00","pubTimestamp":1762171200,"startTime":"0","endTime":"0","summary":"BOSTON, Nov.  03, 2025  (GLOBE NEWSWIRE) -- Monte Rosa Therapeutics, Inc. (Nasdaq: GLUE), a clinical-stage biotechnology company developing novel molecular glue degrader (MGD)-based medicines, today a","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/11/03/3179046/0/en/Monte-Rosa-Therapeutics-to-Participate-in-Upcoming-Investor-Conferences.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4588","XLV","BK4539","BK4585","LABU","XBI","BK4139","GLUE","BK4581"],"gpt_icon":0},{"id":"2578742676","title":"Monte Rosa Therapeutics Advances with MRT-8102: A Promising Phase 1 Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2578742676","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2578742676?lang=en_us&edition=fundamental","pubTime":"2025-10-28 06:19","pubTimestamp":1761603584,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics, Inc. (($GLUE)) announced an update on their ongoing clinical study. Monte Rosa Therapeutics, Inc. is conducting a Phase 1 ...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/monte-rosa-therapeutics-advances-with-mrt-8102-a-promising-phase-1-study?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/monte-rosa-therapeutics-advances-with-mrt-8102-a-promising-phase-1-study?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["MRT","BK4230","BK4539","BK4139","GLUE"],"gpt_icon":0},{"id":"2577365518","title":"Guggenheim Sticks to Their Buy Rating for Monte Rosa Therapeutics (GLUE)","url":"https://stock-news.laohu8.com/highlight/detail?id=2577365518","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2577365518?lang=en_us&edition=fundamental","pubTime":"2025-10-24 19:16","pubTimestamp":1761304589,"startTime":"0","endTime":"0","summary":"In a report released yesterday, Michael Schmidt from Guggenheim maintained a Buy rating on Monte Rosa Therapeutics, with a price target of $16.00. ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/guggenheim-sticks-to-their-buy-rating-for-monte-rosa-therapeutics-glue-blurbs?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/guggenheim-sticks-to-their-buy-rating-for-monte-rosa-therapeutics-glue-blurbs?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["GLUE"],"gpt_icon":0},{"id":"2577826590","title":"Monte Rosa Therapeutics Unveils Preclinical Data on MRT-6160 for Autoimmune Diseases","url":"https://stock-news.laohu8.com/highlight/detail?id=2577826590","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2577826590?lang=en_us&edition=fundamental","pubTime":"2025-10-24 19:00","pubTimestamp":1761303624,"startTime":"0","endTime":"0","summary":"Monte Rosa Therapeutics Inc. announced that it will present new preclinical data on MRT-6160, a VAV1-directed molecular glue degrader, at ACR Convergence 2025, held October 24-29 in Chicago, IL. The data will be presented in a poster session on October 26 at 10:30 am CDT. Preclinical results demonstrate that MRT-6160 inhibited disease pathology, including proteinuria, lymphadenopathy, skin lesion formation, autoantibody production, and organomegaly, in a spontaneous autoimmune disease mouse model. The findings support the potential of MRT-6160 to address multiple rheumatic autoimmune and inflammatory diseases, such as Sjgren's disease, systemic lupus erythematosus, and rheumatoid arthritis. According to the company, MRT-6160 attenuated T and B cell effector functions and reduced disease progression in preclinical studies. Further development toward Phase 2 clinical studies is underway.Disclaimer: This news brief was created by Public Technologies  using generative artificial intelligen","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20251024:nNDL6wTVPS:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2095319765.USD","LU2210150020.SGD","LU0314104364.USD","BK4539","BK4585","BK4588","IE00B64PRP62.GBP","BK4139","GLUE","IE00BKPKM429.USD","BK4112","NDAQ","LU2210149790.SGD","IE00B3QW5Z07.USD","IE00BGHQF748.EUR"],"gpt_icon":0}],"pageSize":20,"totalPage":4,"pageCount":4,"totalSize":78,"code":"91000000","status":"200"}]}}