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Yervoy in First-Line Colorectal Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2494032546","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2494032546?lang=en_us&edition=fundamental","pubTime":"2024-12-25 00:06","pubTimestamp":1735056360,"startTime":"0","endTime":"0","summary":"Bristol Myers Squibb BMY announced that the European Commission has approved the combination of its blockbuster immuno-oncology drug Opdivo  and Yervoy  for a new cancer indication.The EC has approved Opdivo plus Yervoy for the first-line treatment of adult patients with microsatellite instability–high  or mismatch repair deficient  unresectable or metastatic colorectal cancer .Following the latest nod, Opdivo plus Yervoy became the first dual checkpoint inhibitor therapy to be approved for the first-line treatment of MSI-H/dMMR mCRC in the European Union.The Committee for Medicinal Products for Human Use of the European Medicines Agency recommended approval of Opdivo plus Yervoy for the given indication in November.Year to date, shares of Bristol Myers have rallied 12.2% against the industry’s decline of 13.7%.The latest approval for Opdivo plus Yervoy in first-line MSI-H/dMMR mCRC was based on data from the phase III CheckMate -8HW study.Also, the safety profile of Opdivo plus 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Doses First Patient in Phase 1 Trial of Potential Cancer Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2493763831","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493763831?lang=en_us&edition=fundamental","pubTime":"2024-12-23 22:07","pubTimestamp":1734962847,"startTime":"0","endTime":"0","summary":"Immunocore Holdings  said Monday it has dosed the first patient in a phase 1 trial of IMC-P115C, a half-life extended Immune mobilizing monoclonal T-cell receptor against cancer, or ImmTAC, candidate.The drug candidate was developed to improve patient convenience by reducing the frequency of treatment administration, the company said.The phase 1 trial will assess the safety, pharmacokinetics and clinical activity of IMC-P115C in patients with a specific type of advanced solid tumor.According to the company, ImmTAC molecules are designed to redirect the immune system to recognize and kill cancerous cells.Shares of the company rose more than 5% in recent premarket activity Monday.Price: 30.00, Change: +1.67, Percent Change: +5.91","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","IMCR","BK4505"],"gpt_icon":0},{"id":"2493765825","title":"Buy 5 Genomics & Synthetic Biology Stocks Likely to Soar in Short Term","url":"https://stock-news.laohu8.com/highlight/detail?id=2493765825","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493765825?lang=en_us&edition=fundamental","pubTime":"2024-12-23 20:49","pubTimestamp":1734958140,"startTime":"0","endTime":"0","summary":"Genomics companies analyze and interpret genetic information to uncover insights about genetic variations and disease mechanisms and develop tests, therapies and technologies to advance personalized medicine.Companies in synthetic biology, engineer biological systems for practical applications, including pharmaceuticals and agriculture, using genetic engineering and biotechnology techniques to design novel organisms and processes. The promise of curing genetic diseases and extending human lifespan positions these industries for substantial growth.We recommend five small and mid-sized Genomics & Synthetic Biology stocks with a favorable Zacks Rank that are set to skyrocket in near future. These stocks are: CRISPR Therapeutics AG CRSP, Immunocore Holdings plc IMCR, Monte Rosa Therapeutics Inc. GLUE, Rigel Pharmaceuticals Inc. RIGL and Castle Biosciences Inc. CSTL.Pros and Cons of Genomics & Synthetic Biology Space. Genomics enables tailored treatments to individuals based on their geneti","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/_9OKqED6rOANF8VtUei37A--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/5d5a6eb884ce28277f39a4369974b5ea","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/_9OKqED6rOANF8VtUei37A--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/5d5a6eb884ce28277f39a4369974b5ea"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/buy-5-genomics-synthetic-biology-124900313.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IMCR","BK4539","BK4505","BK4139","CRSP","CSTL","BK4556","GLUE","BK4588","RIGL","LU1861558580.USD","BK4585","BK4196","LU1861559042.SGD"],"gpt_icon":1},{"id":"2493756282","title":"Immunocore Announces First Patient Dosed in the Phase 1 Trial of Imc-P115c, a Half-Life Extended (Hle) Immtac Candidate in Patients With Tumors That Express Prame","url":"https://stock-news.laohu8.com/highlight/detail?id=2493756282","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493756282?lang=en_us&edition=fundamental","pubTime":"2024-12-23 20:00","pubTimestamp":1734955201,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241223:nTUA6DZWPK:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4505","BK4139","IMCR"],"gpt_icon":0},{"id":"2492956606","title":"Immunocore announces treatment of first patient in Phase 1/2 trial of IMC-R117C","url":"https://stock-news.laohu8.com/highlight/detail?id=2492956606","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492956606?lang=en_us&edition=fundamental","pubTime":"2024-12-17 20:05","pubTimestamp":1734437120,"startTime":"0","endTime":"0","summary":"Immunocore (IMCR) announces that the first patient has been treated in the Phase 1/2 trial of its novel ImmTAC candidate, IMC-R117C, targeting PIWI...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/immunocore-announces-treatment-of-first-patient-in-phase-1-2-trial-of-imc-r117c?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/immunocore-announces-treatment-of-first-patient-in-phase-1-2-trial-of-imc-r117c?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IMCR","BK4505","BK4139"],"gpt_icon":0},{"id":"2492623955","title":"Immunocore Announces Treatment of First Patient in the Phase 1/2 Trial of Imc-R117c Targeting Piwil1 in Advanced Gastrointestinal Cancers","url":"https://stock-news.laohu8.com/highlight/detail?id=2492623955","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492623955?lang=en_us&edition=fundamental","pubTime":"2024-12-17 20:00","pubTimestamp":1734436800,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241217:nTUA2KLVKR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IMCR","BK4505","BK4139"],"gpt_icon":0},{"id":"2491302522","title":"Why Are Amicus, Immunocore, & Immuneering Stocks Trading Lower On Friday?","url":"https://stock-news.laohu8.com/highlight/detail?id=2491302522","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491302522?lang=en_us&edition=fundamental","pubTime":"2024-12-14 03:10","pubTimestamp":1734117050,"startTime":"0","endTime":"0","summary":"Morgan Stanley downgraded Amicus Therapeutics Inc . Over the last year, the company has executed well commercially, met its goals financially by achieving nonGAAP profitability for 2024, and settled its Galafold patent litigation with Teva Pharmaceutical Industries Ltd.The analyst notes that Amicus is well-positioned, but expectations have increased with the company’s progress, which are now largely priced into shares.The analyst downgraded the stock to Equal-weight from Overweight and lowered the price target from $17 to $12.Investors have shifted focus to what will provide the company’s next leg of growth. The analyst would look to see potential updates to the company’s pipeline in 2025 and beyond, as those programs have the greatest potential to unlock further value for Amicus stock.Morgan Stanley has also lowered the price target for Immunocore Holdings plc  from $74 to $35 on launch timing and pricing for brenetafusp given disappointing data earlier this year in cutaneous melanoma","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/uI4OafKdqumkkqx_HY1gvw--~B/aD01NjM7dz0xMDAwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/Benzinga/83e707c5ba3952b58fca54fa366205fe","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/uI4OafKdqumkkqx_HY1gvw--~B/aD01NjM7dz0xMDAwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/Benzinga/83e707c5ba3952b58fca54fa366205fe"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/why-amicus-immunocore-immuneering-stocks-191050213.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["TSYW.SI","MNQmain","LU1162221912.USD","LU2089284900.SGD","BK4139",".IXIC","NVIW.SI","PSQ","USAW.SI","USJW.SI","LU2271345857.HKD","QID","BK4534","LU1363072403.SGD","BK4585","TQQQ","BK4581","LU2065169927.USD","LU1074936037.SGD","LU1989772923.USD","BK4588","IE00BZ1G4Q59.USD","SQQQ","LU1720051017.SGD","LU0267386448.USD","BK4563","BK4505","LU0320765646.SGD","NQmain","BK4127","LU2065170008.USD","LU0006306889.USD","QLD","BK4539","FOLD","IE00BKVL7J92.USD","LU2089283258.USD","LU2111349929.HKD","LU0158827948.USD","IMRX","LU0971096721.USD","LU1989772840.SGD","LU0158827781.USD","LU0314104364.USD","LU2065171402.SGD","IMCR","LU0106831901.USD","BK4504","LU0098860793.USD"],"gpt_icon":1},{"id":"2491329717","title":"Immunocore Holdings Cut to Equal-Weight From Overweight by Morgan Stanley","url":"https://stock-news.laohu8.com/highlight/detail?id=2491329717","media":"Dow Jones","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491329717?lang=en_us&edition=fundamental","pubTime":"2024-12-13 20:11","pubTimestamp":1734091860,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/IMCR/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 13, 2024 07:11 ET (12:11 GMT)","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IMCR"],"gpt_icon":0},{"id":"2491261383","title":"Morgan Stanley Downgrades Immunocore Holdings to Equalweight From Overweight, Cuts Price Target to $35 From $74","url":"https://stock-news.laohu8.com/highlight/detail?id=2491261383","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491261383?lang=en_us&edition=fundamental","pubTime":"2024-12-13 19:47","pubTimestamp":1734090423,"startTime":"0","endTime":"0","summary":"Immunocore Holdings (IMCR) has an average rating of overweight and mean price target of $65.13, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research fro","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["IMCR"],"gpt_icon":0},{"id":"2491358247","title":"All You Need to Know About Immunocore (IMCR) Rating Upgrade to Strong Buy","url":"https://stock-news.laohu8.com/highlight/detail?id=2491358247","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491358247?lang=en_us&edition=fundamental","pubTime":"2024-12-13 01:00","pubTimestamp":1734022812,"startTime":"0","endTime":"0","summary":"Immunocore Holdings PLC Sponsored ADR  could be a solid choice for investors given its recent upgrade to a Zacks Rank #1 . This rating change essentially reflects an upward trend in earnings estimates -- one of the most powerful forces impacting stock prices.The Zacks rating relies solely on a company's changing earnings picture. It tracks EPS estimates for the current and following years from the sell-side analysts covering the stock through a consensus measure -- the Zacks Consensus Estimate.The power of a changing earnings picture in determining near-term stock price movements makes the Zacks rating system highly useful for individual investors, since it can be difficult to make decisions based on rating upgrades by Wall Street analysts. These are mostly driven by subjective factors that are hard to see and measure in real time.As such, the Zacks rating upgrade for Immunocore is essentially a positive comment on its earnings outlook that could have a favorable impact on its stock pr","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/OL7xfT5pzuzwP2wxb1pcSw--~B/aD02MjU7dz05MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/7ea641b46fe75c0a913349e5e610d6a2","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/OL7xfT5pzuzwP2wxb1pcSw--~B/aD02MjU7dz05MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/7ea641b46fe75c0a913349e5e610d6a2"],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/know-immunocore-imcr-rating-upgrade-170012625.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IMCR"],"gpt_icon":0},{"id":"2491336030","title":"CORT's Dazucorilant Fails to Meet Goal in Neurologic Disorder Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2491336030","media":"Zacks","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491336030?lang=en_us&edition=fundamental","pubTime":"2024-12-12 23:21","pubTimestamp":1734016860,"startTime":"0","endTime":"0","summary":"Corcept Therapeutics Incorporated CORT announced data from the phase II DAZALS study evaluating its selective cortisol modulator, dazucorilant, for treating patients with amyotrophic lateral sclerosis , a degenerative neurologic disorder.The double-blind, placebo-controlled DAZALS study evaluated two doses of dazucorilant  for treating patients with ALS.The study did not meet its primary endpoint, which was the change from baseline in the ALS Functional Rating Scale-Revised  in patients treated with dazucorilant versus those treated with placebo.Shares of Corcept were down in pre-market trading on Dec. 12 following the announcement of the news on Dec. 11.Year to date, shares of Corcept have rallied 85% against the industry’s decline of 4.6%.Data from the study showed that patients who were treated with dazucorilant experienced substantially more gastrointestinal upset compared to those who received placebo at the onset of treatment.Upon completing the study, patients were eligible to e","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/b7YQi_HTDu1GkQZqPUqgyw--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/59b208c03ab625710a229f805a232093","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/b7YQi_HTDu1GkQZqPUqgyw--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/59b208c03ab625710a229f805a232093"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/corts-dazucorilant-fails-meet-goal-152100886.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4505","IMCR","BK4532","SPRO","CORT","BK4007","BK4196","LU0566484027.USD","LU1559883803.SGD","BK4139","CSTL"],"gpt_icon":0},{"id":"2490338665","title":"AnaptysBio Stock Down as Eczema Study Fails to Meet Goals","url":"https://stock-news.laohu8.com/highlight/detail?id=2490338665","media":"Zacks","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490338665?lang=en_us&edition=fundamental","pubTime":"2024-12-12 22:04","pubTimestamp":1734012240,"startTime":"0","endTime":"0","summary":"Shares of AnaptysBio, Inc. ANAB, a clinical-stage biotechnology company, plunged 32.8% on Dec. 11 after it announced that the phase IIb study of pipeline candidate, ANB032, a BTLA agonist, was unsuccessful.Consequently, ANAB discontinued any further investment in this asset.AnaptysBio has lost 27.6% so far this year compared with the industry’s decline of 8.1%.The ARISE-AD study evaluated the efficacy, safety, tolerability, pharmacokinetics and pharmacodynamics of ANB032 monotherapy in patients with moderate-to-severe atopic dermatitis  or eczema.However, ANB032 did not meet the primary endpoint of the proportion of patients who achieved at least a 75% improvement from baseline in Eczema Area and Severity Index score , irrespective of the patient type.Other antibodies in its portfolio include ANB033, an anti-CD122 antagonist, in a phase I study and ANB101, a BDCA2 modulator, soon to enter clinical development.Anaptys also has an immuno-oncology collaboration with GSK plc GSK. 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Enrolls First Patient in Phase 3 Uveal Melanoma Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2490286462","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490286462?lang=en_us&edition=fundamental","pubTime":"2024-12-12 00:00","pubTimestamp":1733932855,"startTime":"0","endTime":"0","summary":"Immunocore (IMCR) and the European Organization for Research and Treatment of Cancer said Wednesday that they enrolled the first patient in the phase 3 trial of tebentafusp as adjuvant treatment for 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randomization of the first patient in t...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/immunocore-eortc-announce-enrollment-of-first-patient-in-phase-3-atom-trial?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/immunocore-eortc-announce-enrollment-of-first-patient-in-phase-3-atom-trial?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4505","BK4147","BK4139","ATOM","IMCR"],"gpt_icon":0},{"id":"2490853210","title":"Eortc and Immunocore Announce Enrolment of First Patient Onto the Only 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chemotherapy alone.Incyte’s lead drug, Jakafi, is a JAK1/JAK2 inhibitor approved for the treatment of polycythemia vera in adults who have had an inadequate response to or are intolerant of hydroxyurea; intermediate or high-risk myelofibrosis , including primary MF, post-polycythemia vera MF and post-essential 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