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These RSU awards were granted as of October 31, 2024  pursuant to the Company's 2022 Inducement Stock Incentive Plan, as amended, as inducements material to the new employees entering into employment with Karyopharm in accordance with Nasdaq Listing Rule 5635.Each RSU award will vest over three years, with 33 1/3% of the shares underlying the RSU award vesting on each of the three consecutive anniversaries of the Grant Date. The vesting of each RSU award is subject to the employee's continued service as an employee of, or other service provider to, Karyopharm through the applicable vesting dates. In addition, each RSU award will be immediately exercisable in full if, on or prior to the first anniversary of the consumma","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/zhDwMCnxitlw66uXF9rtiA--~B/aD04ODt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/9c24beccfa37be9075643e7466ba9fc0","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/zhDwMCnxitlw66uXF9rtiA--~B/aD04ODt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/9c24beccfa37be9075643e7466ba9fc0"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/karyopharm-therapeutics-reports-inducement-grants-200500567.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/karyopharm-therapeutics-reports-inducement-grants-200500567.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139",".IXIC","BK4585","BK4588","IE00B3QW5Z07.USD","LU2210149790.SGD","LU2210150020.SGD","NDAQ","IE00B64PRP62.GBP","IE00BKPKM429.USD","BK4112","IE00BGHQF748.EUR","KPTI","LU2095319765.USD"],"gpt_icon":0},{"id":"2480488882","title":"Karyopharm Therapeutics Inc    expected to post a loss of 26 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2480488882","media":"Reuters","labels":["preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480488882?lang=en_us&edition=fundamental","pubTime":"2024-11-01 22:27","pubTimestamp":1730471256,"startTime":"0","endTime":"0","summary":"* Karyopharm Therapeutics Inc     is expected to show a rise in quarterly revenue when it reports  results on November 5 for the period ending September 30 2024   * The Newton Massachusetts-based  com","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Karyopharm Therapeutics Inc    expected to post a loss of 26 cents a share - Earnings Preview","news_tag":"preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI"],"gpt_icon":0},{"id":"2480706600","title":"Karyopharm Therapeutics Price Target Maintained With a $7.00/Share by HC Wainwright & Co.","url":"https://stock-news.laohu8.com/highlight/detail?id=2480706600","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480706600?lang=en_us&edition=fundamental","pubTime":"2024-11-01 18:00","pubTimestamp":1730455200,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/KPTI/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  November 01, 2024 06:00 ET (10:00 GMT)","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI"],"gpt_icon":0},{"id":"2480902267","title":"Barclays Keeps Their Buy Rating on Karyopharm Therapeutics (KPTI)","url":"https://stock-news.laohu8.com/highlight/detail?id=2480902267","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480902267?lang=en_us&edition=fundamental","pubTime":"2024-11-01 15:15","pubTimestamp":1730445350,"startTime":"0","endTime":"0","summary":"Barclays analyst Peter Lawson maintained a Buy rating on Karyopharm Therapeutics (KPTI – Research Report) today and set a price target of $5.00. Th...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/barclays-keeps-their-buy-rating-on-karyopharm-therapeutics-kpti-2?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/barclays-keeps-their-buy-rating-on-karyopharm-therapeutics-kpti-2?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["KPTI"],"gpt_icon":0},{"id":"2480050351","title":"Karyopharm gains after changes to late-stage trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2480050351","media":"seekingalpha","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2480050351?lang=en_us&edition=fundamental","pubTime":"2024-11-01 02:12","pubTimestamp":1730398359,"startTime":"0","endTime":"0","summary":"ShidlovskiKaryopharm (NASDAQ:KPTI) traded higher on Thursday after the company said, based on feedback from the FDA, it has redesigned its Phase 3 SENTRY Trial for its lead asset selinexor in patients","market":"nz","thumbnail":"https://static.seekingalpha.com/cdn/s3/uploads/getty_images/864745546/image_864745546.jpg?io=getty-c-w750","type":0,"news_type":0,"thumbnails":["https://static.seekingalpha.com/cdn/s3/uploads/getty_images/864745546/image_864745546.jpg?io=getty-c-w750"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://seekingalpha.com/news/4230816-karyopharm-stock-gains-late-stage-trial-changes","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"seekingalpha_trending_news","symbols":["INCY","BK4139","QID","QLD","SQQQ","TQQQ","NQmain","BK4585","MNQmain","PSQ","KPTI","BK4588","BK4550","BK4532",".IXIC"],"gpt_icon":1},{"id":"2479037905","title":"Karyopharm Therapeutics (KPTI) May Report Negative Earnings: Know the Trend Ahead of Q3 Release","url":"https://stock-news.laohu8.com/highlight/detail?id=2479037905","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2479037905?lang=en_us&edition=fundamental","pubTime":"2024-10-31 22:02","pubTimestamp":1730383320,"startTime":"0","endTime":"0","summary":"Wall Street expects a year-over-year increase in earnings on higher revenues when Karyopharm Therapeutics  reports results for the quarter ended September 2024. While this widely-known consensus outlook is important in gauging the company's earnings picture, a powerful factor that could impact its near-term stock price is how the actual results compare to these estimates.The earnings report might help the stock move higher if these key numbers are better than expectations. On the other hand, if they miss, the stock may move lower.While the sustainability of the immediate price change and future earnings expectations will mostly depend on management's discussion of business conditions on the earnings call, it's worth handicapping the probability of a positive EPS surprise.This pharmaceutical company is expected to post quarterly loss of $0.27 per share in its upcoming report, which represents a year-over-year change of +10%.Revenues are expected to be $38.15 million, up 5.9% from the ye","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/9tpS8u8rAmiEoUItmUZeOA--~B/aD02MDE7dz05MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/090f58c1efbe3555b861102525e50b39","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/9tpS8u8rAmiEoUItmUZeOA--~B/aD02MDE7dz05MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/090f58c1efbe3555b861102525e50b39"],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/karyopharm-therapeutics-kpti-may-report-140200309.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IONS","KPTI"],"gpt_icon":0},{"id":"2479085063","title":"Karyopharm to Report Third Quarter 2024 Financial Results on November 5, 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2479085063","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2479085063?lang=en_us&edition=fundamental","pubTime":"2024-10-31 20:00","pubTimestamp":1730376000,"startTime":"0","endTime":"0","summary":"-- Conference Call Scheduled for Tuesday, November 5, 2024, at 8:00 a.m. ET --. NEWTON, Mass., Oct. 31, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. , a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced it will report third quarter 2024 financial results on Tuesday, November 5, 2024. Karyopharm's management team will host a conference call and audio webcast at 8:00 a.m. ET on Tuesday, November 5, 2024, to discuss the financial results and other company updates.XPOVIO and NEXPOVIO are registered trademarks of Karyopharm Therapeutics Inc. Any other trademarks referred to in this release are the property of their respective owners.","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/zhDwMCnxitlw66uXF9rtiA--~B/aD04ODt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/9c24beccfa37be9075643e7466ba9fc0","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/zhDwMCnxitlw66uXF9rtiA--~B/aD04ODt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/9c24beccfa37be9075643e7466ba9fc0"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/karyopharm-report-third-quarter-2024-120000173.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/karyopharm-report-third-quarter-2024-120000173.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","KPTI"],"gpt_icon":0},{"id":"2479707419","title":"BRIEF-Karyopharm Announces Favorable Change In Co-Primary Endpoint For Pivotal Phase 3 SENTRY Trial In Myelofibrosis","url":"https://stock-news.laohu8.com/highlight/detail?id=2479707419","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2479707419?lang=en_us&edition=fundamental","pubTime":"2024-10-31 19:33","pubTimestamp":1730374399,"startTime":"0","endTime":"0","summary":"Oct 31  - Karyopharm Therapeutics Inc   :   * KARYOPHARM ANNOUNCES FAVORABLE CHANGE IN CO-PRIMARY ENDPOINT FOR PIVOTAL PHASE 3 SENTRY TRIAL IN MYELOFIBROSIS   * KARYOPHARM THERAPEUTICS INC - CO-PRIMARY ENDPOINT CHANGED TO ABSOLUTE TOTAL SYMPTOM SCORE    * KARYOPHARM THERAPEUTICS INC - SPLEEN VOLUME RESPONSE RATE ≥ 35%  REMAINS CO-PRIMARY ENDPOINT   * KARYOPHARM THERAPEUTICS INC - SENTRY TRIAL SAMPLE SIZE INCREASED TO APPROXIMATELY 350 PATIENTSSource text:    Further company coverage:    ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","KPTI"],"gpt_icon":0},{"id":"2479870783","title":"Karyopharm Therapeutics Inc - 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Spleen Volume Response Rate ≥ 35%  Remains a Co-primary Endpoint. Promising Improvement inAbs-TSS and SVR35 from Phase 1 Trial of Selinexor in Combination with Ruxolitinib Adds Confidence in Phase 3 SENTRY Trial. NEWTON, Mass., Oct. 31, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. , a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that, following feedback from the U.S. Food and Drug Administration , the Company will be replacing TSS50, one of the co-primary endpoints in the Phase 3 SENTRY Trial  with Abs-TSS. Abs-TSS measures the average improvement in patient symptom scores over 24 weeks relative to the patient's baseline symptom score.\"Our confidence in the success of our Phase 3 SENTRY trial increases based on the change in the co-primary endpoint to Abs-TSS, the increased sample size and the da","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/zhDwMCnxitlw66uXF9rtiA--~B/aD04ODt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/9c24beccfa37be9075643e7466ba9fc0","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/zhDwMCnxitlw66uXF9rtiA--~B/aD04ODt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/9c24beccfa37be9075643e7466ba9fc0"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/karyopharm-announces-favorable-change-co-113000223.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/karyopharm-announces-favorable-change-co-113000223.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","KPTI"],"gpt_icon":0},{"id":"2479768689","title":"Karyopharm to Host Investor Event With Leading Myelofibrosis Kols and Provide a Favorable Study Design Update on October 31, 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2479768689","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2479768689?lang=en_us&edition=fundamental","pubTime":"2024-10-31 04:30","pubTimestamp":1730320205,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241030:nTUA7DCCYB:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["KPTI","BK4139"],"gpt_icon":0},{"id":"2479763463","title":"Karyopharm to Host Investor Event with Leading Myelofibrosis KOLs and Provide a Favorable Study Design Update on October 31, 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2479763463","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2479763463?lang=en_us&edition=fundamental","pubTime":"2024-10-31 04:30","pubTimestamp":1730320200,"startTime":"0","endTime":"0","summary":"Company to host a conference call tomorrow at 8:00 a.m. ET. NEWTON, Mass., Oct. 30, 2024 /PRNewswire/ -- Karyopharm Therapeutics Inc. , a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced it will host a conference call and audio webcast at 8:00 a.m. ET on Thursday, October 31, 2024 to provide a favorable study design update on the Company's pivotal Phase 3 SENTRY study in JAKi naive myelofibrosis.The call will feature leading myelofibrosis key opinion leaders Dr. Raajit Rampal, Director of the Center for Hematologic Malignancies and Director of the Myeloproliferative Neoplasms Program at Memorial Sloan Kettering Cancer Center and Dr.John Mascarenhas, principal investigator of the Phase 3 SENTRY trial, Professor of Medicine at the Icahn School of Medicine at Mount Sinai and Director of the Center of Excellence for Blood Cancers and Myeloid Disorders.","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/zhDwMCnxitlw66uXF9rtiA--~B/aD04ODt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/9c24beccfa37be9075643e7466ba9fc0","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/zhDwMCnxitlw66uXF9rtiA--~B/aD04ODt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/9c24beccfa37be9075643e7466ba9fc0"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/karyopharm-host-investor-event-leading-203000345.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/karyopharm-host-investor-event-leading-203000345.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4218","BK4181","BK4588","KPTI","BK4585","HST","BK4139"],"gpt_icon":0},{"id":"2479283110","title":"Karyopharm Therapeutics Inc    expected to post a loss of 26 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2479283110","media":"Reuters","labels":["preview"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2479283110?lang=en_us&edition=fundamental","pubTime":"2024-10-29 21:53","pubTimestamp":1730210022,"startTime":"0","endTime":"0","summary":"* Karyopharm Therapeutics Inc     is expected to show a rise in quarterly revenue when it reports  results on October 31 (estimated) for the period ending September 30 2024   * The Newton Massachusett","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":"Karyopharm Therapeutics Inc    expected to post a loss of 26 cents a share - Earnings Preview","news_tag":"preview","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["KPTI"],"gpt_icon":0}],"pageSize":16,"totalPage":7,"pageCount":6,"totalSize":98}]}}