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Dr. Tiago Reis Marques, Chief Executive Officer of Pasithea stated, “We are pleased to observe that as we continue to dose escalate, we have not yet seen rash emerge. Rash is a common adverse event  that is observed at low doses with competitor MEK inhibitors and may lead to the high discontinuation rate in real world practice. In addition, we are excited to dose patients with our potential commercial formulation.”Pasithea is a biotechnology company focused on the discovery, research and development of innovative treatments for central nervous system  disorders and RASopathies. 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memory and storage product maker's revenue above Wall Street's estimates.Shares climbed more than 13% Thursday, with intraday trading volume at over 83.8 million compared with a daily average of about 24.3 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of Pasithea Therapeutics Rise 77.4% on Positive Early-Stage Data From Cancer Drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2470306787","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470306787?lang=en_us&edition=fundamental","pubTime":"2024-09-26 22:28","pubTimestamp":1727360908,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20240926:nFWN3L80W6:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["KTTA","BK4139"],"gpt_icon":0},{"id":"2470773771","title":"Pasithea Therapeutics Shares Move Higher After Positive Data for Cancer Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2470773771","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470773771?lang=en_us&edition=fundamental","pubTime":"2024-09-26 22:20","pubTimestamp":1727360400,"startTime":"0","endTime":"0","summary":"Pasithea Therapeutics shares jumped after the company said it saw positive results in data from a trial for PAS-004 for the treatment of neurofibromatosis type 1 and other cancer indications.Shares of the biotechnology company were up 76% at $6.78, and are down 28% in the past 12 months.The Phase 1 study showed positive safety, tolerability, pharmacokinetic and preliminary efficacy data from the first two cohorts of patients, being conducted at four clinical sites in the U.S.The Miami company said plasma exposure increased with an increase in dose, and PAS-004's long half-life of about 70 hours will allow for once-daily dosing or longer intervals.No treatment-related adverse events or dose-limiting toxicities were observed to date, the company said. In the first two dosing cohorts, PAS-004 was shown to be well-tolerated with a favorable safety profile with no drug-related dose interruptions, reductions or discontinuations.A study-independent Safety Review Committee has completed its sa","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","KTTA","BK4139"],"gpt_icon":0},{"id":"2470736587","title":"Why Is Pasithea Therapeutics Stock Surging On Thursday?","url":"https://stock-news.laohu8.com/highlight/detail?id=2470736587","media":"Benzinga","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470736587?lang=en_us&edition=fundamental","pubTime":"2024-09-26 20:56","pubTimestamp":1727355401,"startTime":"0","endTime":"0","summary":"On Thursday, Pasithea Therapeutics Corp. announced safety, tolerability, pharmacokinetic , and preliminary efficacy data from the first 2 cohorts of patients (n=6) in its Phase 1 trial of PAS-004 in patients with MAPK pathway-driven advanced solid tumors with a documented RAS, NF1 or RAF mutation or patients who have failed BRAF/MEK inhibition.Pasithea stock is trading higher on a strong volume of 9.01 million versus an average of 17.3k as per data from Benzinga Pro.Plasma exposure increased with an increase in dose, and linear PK was observed.A long half-life of approximately 70 hours will allow for once-daily dosing or longer intervals.Prolonged systemic exposure with minimal fluctuation in PAS-004 plasma concentration at a steady state indicates a potential to achieve constant target inhibition.Also Read: Neurology Focused Pasithea Therapeutics Stock Soars Over 150% Today – Here’s Why. In the first 2 dosing cohorts (n=6), PAS-004 was shown to be well-tolerated with a favorable safet","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/PE85NMCltDiSgZngbbFbqA--~B/aD01NTM7dz05ODM7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/Benzinga/60721e8ba91c96cfb5f5c44671b8c27e","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/PE85NMCltDiSgZngbbFbqA--~B/aD01NTM7dz05ODM7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/Benzinga/60721e8ba91c96cfb5f5c44671b8c27e"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/why-pasithea-therapeutics-stock-surging-125641743.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PK","KTTA","BK4181","KTTAW","BK4139","LENZ","BK4218"],"gpt_icon":0},{"id":"2470336117","title":"BUZZ-Pasithea Therapeutics rises on positive early-stage data from cancer drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2470336117","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470336117?lang=en_us&edition=fundamental","pubTime":"2024-09-26 20:34","pubTimestamp":1727354069,"startTime":"0","endTime":"0","summary":"** Shares of drug developer Pasithea Therapeutics    rise 64.3% to $6.31 premarket    ** KTTA says its experimental cancer drug, PAS-004, was safe and well tolerated in an early-stage study   ** Says one heavily pre-treated patient with stage three colon cancer showed prolonged stable disease     ** Co is testing the drug in certain cancer patients whose tumor has an RAF mutation    ** Says no treatment-related adverse events were observed and no drug-related dose interruptions or discontinuations   ** Co expects to provide additional trial updates on a periodic basis as the trial progresses   ** Up to last close, stock down 48% YTD ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","KTTA","BK4139"],"gpt_icon":0},{"id":"2470478052","title":"Top Premarket Gainers","url":"https://stock-news.laohu8.com/highlight/detail?id=2470478052","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470478052?lang=en_us&edition=fundamental","pubTime":"2024-09-26 20:03","pubTimestamp":1727352233,"startTime":"0","endTime":"0","summary":"Telesis Bio (TBIO) shares increased more than two-fold pre-bell Thursday after the company said it teamed up with Beckman Coulter Life Sciences to create scalable biofoundries.Pasithea Therapeutics 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Therapeutics Says Interim Phase 1 Data Show Tumor Drug Candidate's Efficacy, Safety; Shares Rise Pre-Bell","url":"https://stock-news.laohu8.com/highlight/detail?id=2470201787","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470201787?lang=en_us&edition=fundamental","pubTime":"2024-09-26 19:56","pubTimestamp":1727351817,"startTime":"0","endTime":"0","summary":"Pasithea Therapeutics  said Thursday that interim data from a phase 1 study showed that its experimental drug, PAS-004, was effective and safe in treating neurofibromatosis type 1 and other cancer indications.The company said PAS-004's long half-life of about 70 hours enables once-daily or less frequent oral dosing compared with previous versions of the drug, which required twice-daily dosing and exhibited short half-lives.Pasithea also said that the drug's pharmacokinetic profile indicated consistent plasma levels at a steady state, which may reduce the risk of toxicity related to peak concentrations.The drug developer said that the study results support the advancement of PAS-004 into clinical trials for treating cutaneous and plexiform neurofibromas in NF1, as well as other MAPK-driven conditions.The company plans to provide additional trial updates periodically as the trial progresses.Shares of the company rose more than 63% in premarket activity Thursday.Price: 6.2800, Change: +2.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LENZ","KTTA","BK4139"],"gpt_icon":0},{"id":"2470781782","title":"BRIEF-Pasithea Therapeutics Announces Positive Efficacy Data From Its Phase 1 Clinical Trial Of Pas-004 In Advanced Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2470781782","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470781782?lang=en_us&edition=fundamental","pubTime":"2024-09-26 19:07","pubTimestamp":1727348879,"startTime":"0","endTime":"0","summary":"Sept 26  - Pasithea Therapeutics Corp   :   * PASITHEA THERAPEUTICS ANNOUNCES POSITIVE INITIAL SAFETY, TOLERABILITY, PHARMACOKINETIC , AND PRELIMINARY EFFICACY DATA FROM ITS PHASE 1 CLINICAL TRIAL OF PAS-004 IN ADVANCED CANCER   * PASITHEA THERAPEUTICS CORP - PATIENT WITH STAGE 3 COLON CANCER ACHIEVES PROLONGED STABLE DISEASE   * PASITHEA THERAPEUTICS CORP - NO TREATMENT-RELATED ADVERSE EVENTS OR DOSE-LIMITING TOXICITIES OBSERVEDSource text for Eikon:    Further company coverage:    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