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lines.At high doses above 76 mg/m2, the confirmed ORR among evaluable patients was 22%  across all B7-H4 high tumors.Additionally, 78%  had ≥30% tumor reduction in target lesions.Mersana is implementing proteinuria mitigation efforts and continues to examine higher doses in dose escalation and backfill cohorts ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/why-cancer-focused-mersana-therapeutics-174937358.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4563","BK4139","MRSN","LENZ"],"gpt_icon":0},{"id":"2502529038","title":"BUZZ-Mersana rises on FDA's 'fast track' tag for cancer drug, early-stage trial 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Friday that the US Food and Drug Administration recently granted an additional Fast Track designation to XMT-1660 for the treatment of advanced or metastatic breast cancer in patients with human epidermal growth factor receptor 2 low or HER2-negative disease, including triple-negative breast cancer, who have received a prior topoisomerase-1 inhibitor antibody-drug conjugate, the company said.The FDA previously granted the drug Fast Track designation for the treatment of adult patients with advanced or metastatic recurrent triple-negative breast cancer.The company also said that the World Health Organization has approved emiltatug ledadotin as XMT-1660's international nonproprietary name.Shares of the company were up more than 15% in Friday's premarket activity.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4563","MRSN","LENZ","BK4139","FAST"],"gpt_icon":0},{"id":"2502851144","title":"Mersana Shares Rise on Advances With Breast-Cancer Treatment","url":"https://stock-news.laohu8.com/highlight/detail?id=2502851144","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2502851144?lang=en_us&edition=fundamental","pubTime":"2025-01-10 19:45","pubTimestamp":1736509500,"startTime":"0","endTime":"0","summary":"Mersana Therapeutics shares rose sharply after the biopharmaceutical company won a second Food and Drug Administration fast-track designation for a proposed treatment for breast cancer and reported positive early stage study results for the drug.Mersana on Friday said the new designation covers the drug, XMT-1660, for the treatment of advanced or metastatic breast cancer in patients with human epidermal growth factor receptor 2 low or HER2-negative disease, including triple-negative breast cancer, who have received a prior topoisomerase-1 inhibitor antibody-drug conjugate.Mersana shares, which closed Wednesday at $1.30, were recently up 22% at $1.59 in premarket trading.The FDA's fast-track program is designed to facilitate the development and expedite the review of treatments for serious or potentially life-threatening illnesses with high unmet medical needs.The agency previously granted fast-track designation to XMT-1660 for the treatment of adults with advanced or metastatic recurre","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4563","MRSN","BK4139"],"gpt_icon":0},{"id":"2502516518","title":"Mersana Therapeutics Shares up 22.3% at $1.59 Premarket on FDA's Fast Track Tag for Cancer Drug, Early Stage Trial Data","url":"https://stock-news.laohu8.com/highlight/detail?id=2502516518","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2502516518?lang=en_us&edition=fundamental","pubTime":"2025-01-10 19:40","pubTimestamp":1736509221,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250110:nFWN3O60HY:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["MRSN","BK4563","BK4139"],"gpt_icon":0},{"id":"2502785165","title":"Mersana Therapeutics Says Initial Data From Cancer Drug Trial Shows Promise, Shares Rise Premarket","url":"https://stock-news.laohu8.com/highlight/detail?id=2502785165","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2502785165?lang=en_us&edition=fundamental","pubTime":"2025-01-10 19:37","pubTimestamp":1736509034,"startTime":"0","endTime":"0","summary":"Mersana Therapeutics (MRSN) said Friday initial clinical data from the phase 1 study of its lead candidate, emiltatug ledadotin, targeting B7-H4, showed clinical activity across multiple tumor types a","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","BK4563","LENZ","MRSN"],"gpt_icon":0},{"id":"2502104856","title":"Mersana Therapeutics: FDA grants additional Fast Track designation to XMT-1660","url":"https://stock-news.laohu8.com/highlight/detail?id=2502104856","media":"TIPRANKS","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2502104856?lang=en_us&edition=fundamental","pubTime":"2025-01-10 19:11","pubTimestamp":1736507480,"startTime":"0","endTime":"0","summary":"Mersana Therapeutics (MRSN) announced the U.S. FDA recently granted an additional Fast Track designation to XMT-1660. The company also announced th...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/mersana-therapeutics-fda-grants-additional-fast-track-designation-to-xmt-1660?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/mersana-therapeutics-fda-grants-additional-fast-track-designation-to-xmt-1660?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["IE00BFXG0V08.USD","MRSN","BK4567","BK4104","BK4585","IE00BYQQ9H92.USD","BK4139","LENZ","IE00B5TLWC47.USD","BK4563","FAST","BK4588"],"gpt_icon":0},{"id":"2502856192","title":"Mersana Therapeutics: ‘Positive’ results from Phase 1 emiltatug ledadotin trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2502856192","media":"TIPRANKS","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2502856192?lang=en_us&edition=fundamental","pubTime":"2025-01-10 19:05","pubTimestamp":1736507107,"startTime":"0","endTime":"0","summary":"Mersana Therapeutics (MRSN) announced positive initial clinical data from the Phase 1 dose escalation and backfill cohorts for emiltatug ledadotin,...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/mersana-therapeutics-positive-results-from-phase-1-emiltatug-ledadotin-trial?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/mersana-therapeutics-positive-results-from-phase-1-emiltatug-ledadotin-trial?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["MRSN","BK4563","LENZ","BK4139"],"gpt_icon":0}],"pageSize":16,"totalPage":4,"pageCount":2,"totalSize":54}]}}