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22:15","pubTimestamp":1737036900,"startTime":"0","endTime":"0","summary":"– Newly Completed Sensitivity Analyses Demonstrate Robustness of Previously Announced Survival Superiority Over External Control in Patients with TA-TMA –。Sensitivity analyses support the results of the primary endpoint analysis, with representative sensitivity analyses demonstrating:. Narsoplimab-treated patients had an over 2-fold reduction  to an over 4-fold reduction (hazard ratio = 0.24 [95% confidence interval: 0.13, 0.47] in risk of mortality. The primary endpoint analysis, previously reported on December 19, 2024, showed an over 3-fold reduction in risk of mortality  in TA-TMA patients treated with narsoplimab compared to the external control registry TA-TMA patients not treated with narsoplimab. Omeros plans to resubmit to FDA later this quarter the BLA for narsoplimab to become the first approved therapeutic for TA-TMA, a life-threatening complication of hematopoietic stem cell transplantation; MAA submission to European regulators targeted by mid-year. Overall survival with ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/omeros-announces-statistical-analysis-narsoplimab-141500628.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4007","BK4585","MAA","BK4588","BK4215","OMER"],"gpt_icon":0},{"id":"2494021328","title":"When Can We Expect A Profit From Omeros Corporation (NASDAQ:OMER)?","url":"https://stock-news.laohu8.com/highlight/detail?id=2494021328","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2494021328?lang=en_us&edition=fundamental","pubTime":"2024-12-27 19:35","pubTimestamp":1735299337,"startTime":"0","endTime":"0","summary":"With the business potentially at an important milestone, we thought we'd take a closer look at Omeros Corporation's  future prospects. Omeros Corporation, a clinical-stage biopharmaceutical company, discovers, develops, and commercializes small-molecule and protein therapeutics, and orphan indications targeting immunologic diseases, including complement-mediated diseases, cancers, and addictive and compulsive disorders. The US$579m market-cap company posted a loss in its most recent financial year of US$175m and a latest trailing-twelve-month loss of US$185m leading to an even wider gap between loss and breakeven. The most pressing concern for investors is Omeros' path to profitability – when will it breakeven?We've put together a brief outline of industry analyst expectations for the company, its year of breakeven and its implied growth rate.One thing we would like to bring into light with Omeros is it currently has negative equity on its balance sheet. This can sometimes arise from a","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/expect-profit-omeros-corporation-nasdaq-113537867.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BGHQF748.EUR",".IXIC","QID","USAW.SI","NVIW.SI","NQmain","IE00B3QW5Z07.USD","BK4007","LU2095319765.USD","BK4588","PSQ","LU2210149790.SGD","LU2210150020.SGD","USJW.SI","BK4585","TQQQ","IE00BKPKM429.USD","TSYW.SI","OMER","IE00B64PRP62.GBP","SQQQ","NDAQ","MNQmain","BK4112","QLD"],"gpt_icon":1},{"id":"2493719870","title":"retail investors who own 52% along with institutions invested in Omeros Corporation (NASDAQ:OMER) saw increase in their holdings value last week","url":"https://stock-news.laohu8.com/highlight/detail?id=2493719870","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493719870?lang=en_us&edition=fundamental","pubTime":"2024-12-24 02:18","pubTimestamp":1734977913,"startTime":"0","endTime":"0","summary":"Key Insights Omeros' significant retail investors ownership suggests that the key decisions are influenced by...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/6121000-choice2-main-header/1585186699299"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/pharmaceuticals-biotech/nasdaq-omer/omeros/news/retail-investors-who-own-52-along-with-institutions-invested-4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["TSYW.SI","USJW.SI","LU2210150020.SGD","BK4007","IE00B3QW5Z07.USD","NQmain","QID","IE00BKPKM429.USD","PSQ","IE00BGHQF748.EUR","NDAQ","QLD","BK4112",".IXIC","IE00B64PRP62.GBP","NVIW.SI","TQQQ","BK4585","LU2210149790.SGD","MNQmain","SQQQ","OMER","BK4588","LU2095319765.USD","USAW.SI"],"gpt_icon":1},{"id":"2493759015","title":"Omeros initiated with a Buy at D. Boral Capital","url":"https://stock-news.laohu8.com/highlight/detail?id=2493759015","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2493759015?lang=en_us&edition=fundamental","pubTime":"2024-12-23 20:16","pubTimestamp":1734956162,"startTime":"0","endTime":"0","summary":"D. Boral Capital initiated coverage of Omeros (OMER) with a Buy rating and $36 price target With Narsoplimab now poised for U.S. approval, followed...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/omeros-initiated-with-a-buy-at-d-boral-capital?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/omeros-initiated-with-a-buy-at-d-boral-capital?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OMER","BK4007"],"gpt_icon":0},{"id":"2492005631","title":"Sector Update: Health Care Stocks Lower Thursday Afternoon","url":"https://stock-news.laohu8.com/highlight/detail?id=2492005631","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492005631?lang=en_us&edition=fundamental","pubTime":"2024-12-20 02:49","pubTimestamp":1734634181,"startTime":"0","endTime":"0","summary":"Health care stocks were declining Thursday afternoon, with the NYSE Health Care Index shedding 0.4% and the Health Care Select Sector SPDR Fund  down 0.3%.The iShares Biotechnology ETF  fell 1.1%.In corporate news, Eli Lilly's  tirzepatide injection products Zepbound and Mounjaro are no longer in shortage, the US Food and Drug Administration said Thursday. Eli Lilly shares were down 0.8%.Omeros  shares surged 44% after it said Thursday that its trial of narsoplimab in hematopoietic stem cell transplant-associated thrombotic microangiopathy met its primary endpoint in overall survival.Aquestive Therapeutics  shares jumped 5.6% after it said Thursday that its Libervant buccal film has received seven years of orphan drug exclusivity from the US Food and Drug Administration to treat seizure clusters in patients with epilepsy ages two to five.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["AQST","LU0320765059.SGD","LU1868836757.USD","IE00B4R5TH58.HKD","LU1035775433.USD","IE0009355771.USD","IBB","LU0122379950.USD","LU0640476718.USD","SG9999015986.USD","LU2112291526.USD","LU1291159041.SGD","BK4581","LU0471298694.HKD","LU0417517546.SGD","IE00B1BXHZ80.USD","LLY","LU2468319806.SGD","LU0097036916.USD","LU0823416689.USD","LU2237443622.USD","LU2211815571.USD","BK4588","IE0002141913.USD","BK4516","IE00BJJMRZ35.SGD","LU1023059063.AUD","LU1093756325.SGD","OMER","LU1868836591.USD","SG9999017495.SGD","LU0471298777.SGD","BK4599","LU2237443549.SGD","LU2361044865.SGD","LU0058720904.USD","BK4534","LU0096364046.USD","LU0354030438.USD","LU1551013342.USD","SGXZ51526630.SGD","LU2063271972.USD","LU0689472784.USD","IE0004445239.USD","SG9999018857.SGD","LU0672654240.SGD","SG9999014898.SGD","LU0114720955.EUR","LU0820561909.HKD","XLV"],"gpt_icon":1},{"id":"2492079170","title":"Omeros Stock Gains 52% On Successful Trial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2492079170","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492079170?lang=en_us&edition=fundamental","pubTime":"2024-12-19 23:56","pubTimestamp":1734623760,"startTime":"0","endTime":"0","summary":"Omeros shares gained Thursday after the company shared positive results for a trial of its treatment of a stem-cell transplantation complication.The stock rose 52% to $11.15. It has nearly doubled over the past month and a half after reporting third-quarter earnings in mid-November.The Seattle-based biopharmaceutical company said its narsoplimab treatment met its primary endpoint in a trial.Narsoplimab is a monoclonal antibody designed to treat a complication in stem-cell transplantation called hematopoietic stem cell transplant-associated thrombotic microangiopathy .The trial compared the survival rate of 28 patients with more than 100 patients in a control group who did not receive narsoplimab. Patients receiving the treatment showed significantly better survival rates.Omeros plans to resubmit a biologics license application for its narsoplimab to the Food and Drug Administration as soon as possible, it said. If approved, narsoplimab would be the first approved treatment for TA-TMA, ","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":"Omeros Stock Gains 52% On Successful Trial Results","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OMER","PA3.SI","BK6512","BK4007","BK6045"],"gpt_icon":0},{"id":"2492385105","title":"Omeros Reports Narsoplimab TA-TMA Trial Success; Stock Surges","url":"https://stock-news.laohu8.com/highlight/detail?id=2492385105","media":"GuruFocus.com","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492385105?lang=en_us&edition=fundamental","pubTime":"2024-12-19 23:46","pubTimestamp":1734623201,"startTime":"0","endTime":"0","summary":"As of the latest noted price at the time of writing, Omeros Corporation's  stock price jumped to $12.54, up $5.08 or 68.1%. The rise corresponds with the announcement that its main endpoint in the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy reached a noteworthy mark, so targeting the lectin pathway of complement activation. The outcomes showed a three-fold lower death risk than those of patients not receiving narsoplimab.The business claims that an independent group performed the main statistical analysis and compared general survival rates between 28 narsoplimab-treated patients and over 100 high-risk TA-TMA patients in an external control registry. The study produced a hazard ratio of 0.32 with a p-value of less than 0.00001 and a confidence range of 0.23 to 0.44. Omeros said these findings support the therapeutic effectiveness of narsoplimab.These results lead Omeros to intend to resubmit its Biologics License Application to the U.S. Food an","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/0PB4TOrOAeKHOwqkHI8RbA--~B/aD0zNjY7dz01NTA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/us.finance.gurufocus/35e641d07792297605196243342e6b7f","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/0PB4TOrOAeKHOwqkHI8RbA--~B/aD0zNjY7dz01NTA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/us.finance.gurufocus/35e641d07792297605196243342e6b7f"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/omeros-reports-narsoplimab-ta-tma-154641593.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["OMER","BK4007"],"gpt_icon":0},{"id":"2492177331","title":"Omeros Up Over 66%, On Track for Highest Close Since September 2021 -- Data Talk","url":"https://stock-news.laohu8.com/highlight/detail?id=2492177331","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492177331?lang=en_us&edition=fundamental","pubTime":"2024-12-19 23:27","pubTimestamp":1734622020,"startTime":"0","endTime":"0","summary":"Omeros Corporation  is currently at $12.40, up $4.94 or 66.22%. --Would be highest close since Sept. 30, 2021, when it closed at $13.79. --On pace for largest percent increase since July 1, 2022, when it rose 68.73%. --Up 279.2% year-to-date; on pace for best year on record . --Down 53.54% from its all-time closing high of $26.69 on Sept. 4, 2018. --Up 289.94% from 52 weeks ago , when it closed at $3.18. --Traded as high as $12.62; highest intraday level since Dec. 6, 2024, when it hit $12.65. --Up 69.17% at today's intraday high; largest intraday percent increase since Nov. 14, 2024, when it rose as much as 79.24%","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OMER","BK4007"],"gpt_icon":0},{"id":"2492746511","title":"Omeros' Pivotal Trial of Narsoplimab Meets Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2492746511","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492746511?lang=en_us&edition=fundamental","pubTime":"2024-12-19 22:57","pubTimestamp":1734620267,"startTime":"0","endTime":"0","summary":"Omeros  said Thursday that its pivotal trial of narsoplimab in hematopoietic stem cell transplant-associated thrombotic microangiopathy met its primary endpoint in overall survival.The company said an independent analysis compared overall survival of the trial's 28 patients withover 100 similarly high-risk patients who did not receive narsoplimab treatment, and results showed \"statistically significant superiority\" of overall survival data from the trial's patients.Omeros said it plans to resubmit the biologics license application for narsoplimab to the US Food and Drug Administration as soon as possible.Shares of Omeros were up over 48% in early trading.Price: 11.08, Change: +3.62, Percent Change: +48.53","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["OMER","BK4007"],"gpt_icon":0},{"id":"2492179165","title":"Omeros announces narsoplimab trial meets primary endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2492179165","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492179165?lang=en_us&edition=fundamental","pubTime":"2024-12-19 22:20","pubTimestamp":1734618046,"startTime":"0","endTime":"0","summary":"Omeros (OMER) announced that an independent statistical group has completed the primary statistical analysis agreed with the FDA for narsoplimab, O...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/omeros-announces-narsoplimab-trial-meets-primary-endpoint?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/omeros-announces-narsoplimab-trial-meets-primary-endpoint?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OMER","BK4007"],"gpt_icon":0},{"id":"2492761851","title":"Omeros Corp: to Resubmit a Bla to FDA for Narsoplimab","url":"https://stock-news.laohu8.com/highlight/detail?id=2492761851","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492761851?lang=en_us&edition=fundamental","pubTime":"2024-12-19 22:19","pubTimestamp":1734617980,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241219:nFWN3NK0VF:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4007","OMER"],"gpt_icon":0},{"id":"2492176182","title":"Omeros' Narsoplimab Meets Its Pivotal Trial Primary Endpoint","url":"https://stock-news.laohu8.com/highlight/detail?id=2492176182","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492176182?lang=en_us&edition=fundamental","pubTime":"2024-12-19 22:19","pubTimestamp":1734617980,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241219:nFWN3NK0VF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["OMER","BK4007"],"gpt_icon":0},{"id":"2492179355","title":"Omeros’ Narsoplimab Meets its Pivotal Trial Primary Endpoint – Statistical Analysis Shows Survival Superiority Over External Control in Patients with TA-TMA","url":"https://stock-news.laohu8.com/highlight/detail?id=2492179355","media":"Business Wire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2492179355?lang=en_us&edition=fundamental","pubTime":"2024-12-19 22:15","pubTimestamp":1734617700,"startTime":"0","endTime":"0","summary":"Primary statistical analysis of overall survival compared TA-TMA patients treated with narsoplimab in its pivotal trial to a cohort of over 100 TA-TMA patients not treated with narsoplimab in an external control stem cell transplant registry; FDA-agreed analysis was conducted by an independent external statistical group. \"The results of this comparative survival analysis for narsoplimab in TA-TMA are truly outstanding,\" stated Alessandro Rambaldi, M.D., Professor of Hematology at the University of Milan and Head of the Hematology and Bone Marrow Transplant Unit at ASST Papa Giovanni XXIII in Bergamo, Italy. \"As an investigator in the pivotal clinical trial and having since requested and used narsoplimab in a good number of very sick TA-TMA patients through the expanded access program, we have seen first-hand the impressive benefits of narsoplimab in these high-risk patients. While we do not use C5 inhibitors in our transplant patients, nearly 50 patients in the expanded access program ","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/woUQeP7qpLty8qYTbWsKrw--~B/aD0zNDI7dz00ODA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/business-wire.com/8a2f3eaead10ec9eae764fa1a1ec3651","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/woUQeP7qpLty8qYTbWsKrw--~B/aD0zNDI7dz00ODA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/business-wire.com/8a2f3eaead10ec9eae764fa1a1ec3651"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/omeros-narsoplimab-meets-pivotal-trial-141500583.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["OMER","BK4215","BK4023","BK4585","MAA","SAP","BK4528","HSCT","BK4007","BK4588"],"gpt_icon":0}],"pageSize":16,"totalPage":5,"pageCount":2,"totalSize":67}]}}