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safety profile for ONS-5010.ONS-5010/Lytenava  has already been granted Marketing Authorization in the European Union and the U.K.If approved by the FDA, Outlook Therapeutics plans to commercialize ONS-5010/Lytenava  directly in the U.S. It is also assessing partnering options for Lytenava  in Europe and other 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The shares had ended Tuesday at $4.89, down 38% so far in 2024.Wet age-related macular degeneration is an eye condition that occurs when abnormal blood vessels start to grow beneath the retina.Outlook, which received regulatory approval earlier this year in the European Union and the U.K. for the first authorized use of an ophthalmic formulation of bevacizumab for the treatment of wet age-related macular degeneration, said preliminary data from the trial","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OTLK","BK4139","LENZ"],"gpt_icon":0},{"id":"2486082533","title":"Outlook Therapeutics Says Eye Disease Drug Fails Key Trial Endpoint; Shares Plunge","url":"https://stock-news.laohu8.com/highlight/detail?id=2486082533","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486082533?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:31","pubTimestamp":1732710682,"startTime":"0","endTime":"0","summary":"Outlook Therapeutics (OTLK) said Wednesday preliminary results from the second of two clinical trials evaluating its experimental drug, ONS-5010, an opthalmic formulation of bevacizumab in wet age-rel","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["OTLK","LENZ","BK4139"],"gpt_icon":0},{"id":"2486823677","title":"BUZZ-Outlook Therapeutics slumps as eye disease drug fails to meet key goal in study","url":"https://stock-news.laohu8.com/highlight/detail?id=2486823677","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486823677?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:18","pubTimestamp":1732709906,"startTime":"0","endTime":"0","summary":"** Shares of Outlook Therapeutics    decline 82% to 92 cents before the bell   ** Co says preliminary data shows its experimental drug, ONS-5010, did not achieve non-inferiority goal at week 8 in a late-stage study    ** OTLK says non-inferiority goal was being evaluated after reaching an agreement with US FDA    ** Last year, FDA had declined to approve OTLK's drug citing manufacturing issues and need for further clinical evidence    ** Adds that data showed an improvement in vision, presence of biologic activity and a continued favorable safety profile for ONS-5010    ** OTLK is testing the drug in patients with wet age-related macular degeneration, a condition that can lead to irreversible vision loss   ** Co says final efficacy data from the study is expected in January 2025, plans to resubmit its marketing application to FDA in Q1 next year   ** As of last close, OTLK down 38% YTD ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["OTLK","BK4139","LENZ"],"gpt_icon":0},{"id":"2486828309","title":"BRIEF-Outlook Therapeutics Announces Preliminary Topline Results Of Norse Eight Clinical Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2486828309","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486828309?lang=en_us&edition=fundamental","pubTime":"2024-11-27 20:00","pubTimestamp":1732708807,"startTime":"0","endTime":"0","summary":"BRIEF-Outlook Therapeutics Announces Preliminary Topline Results Of Norse Eight Clinical TrialNov 27 (Reuters) - Outlook Therapeutics Inc OTLK.O:OUTLOOK THERAPEUTICS ANNOUNCES PRELIMINARY TOPLINE RESU","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nTUA3QXLTP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","OTLK"],"gpt_icon":0},{"id":"2486071840","title":"Outlook Therapeutics Shares Fall 53% Premarket After Preliminary Results Show Eye Disorder Drug Failed to Meet Main Goal of Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2486071840","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486071840?lang=en_us&edition=fundamental","pubTime":"2024-11-27 19:57","pubTimestamp":1732708671,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nFWN3MY056:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["OTLK","BK4139"],"gpt_icon":0},{"id":"2486828660","title":"Outlook Therapeutics reports preliminary results from Norse Eight trials","url":"https://stock-news.laohu8.com/highlight/detail?id=2486828660","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486828660?lang=en_us&edition=fundamental","pubTime":"2024-11-27 19:55","pubTimestamp":1732708524,"startTime":"0","endTime":"0","summary":"Outlook Therapeutics (OTLK) announced preliminary topline results of Norse Eight, the second of two adequate and well controlled clinical trials ev...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/outlook-therapeutics-reports-preliminary-results-from-norse-eight-trials?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/outlook-therapeutics-reports-preliminary-results-from-norse-eight-trials?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["OTLK","BK4139","LENZ"],"gpt_icon":0},{"id":"2486840162","title":"Outlook Therapeutics Inc - Final Efficacy Data Expected in January 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2486840162","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486840162?lang=en_us&edition=fundamental","pubTime":"2024-11-27 19:50","pubTimestamp":1732708200,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nTUA3QXLTP:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["OTLK","BK4139"],"gpt_icon":0},{"id":"2486840161","title":"Outlook Therapeutics Inc -Anticipate Resubmission of Bla in Calendar Q1 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2486840161","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486840161?lang=en_us&edition=fundamental","pubTime":"2024-11-27 19:50","pubTimestamp":1732708200,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nTUA3QXLTP:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","OTLK"],"gpt_icon":0},{"id":"2486409118","title":"Outlook Therapeutics® Announces Preliminary Topline Results of Norse Eight Clinical Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2486409118","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486409118?lang=en_us&edition=fundamental","pubTime":"2024-11-27 19:50","pubTimestamp":1732708200,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nTUA3QXLTP:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","OTLK"],"gpt_icon":0},{"id":"2486401648","title":"Outlook Therapeutics Inc - Ons-5010 Did Not Meet Non-Inferiority Endpoint in Norse Eight Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2486401648","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486401648?lang=en_us&edition=fundamental","pubTime":"2024-11-27 19:50","pubTimestamp":1732708200,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241127:nTUA3QXLTP:3","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","OTLK"],"gpt_icon":0},{"id":"2486774980","title":"Owning 30% shares,institutional owners seem interested in Outlook Therapeutics, Inc. (NASDAQ:OTLK),","url":"https://stock-news.laohu8.com/highlight/detail?id=2486774980","media":"Simply Wall St.","labels":["shareholding"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2486774980?lang=en_us&edition=fundamental","pubTime":"2024-11-26 20:32","pubTimestamp":1732624375,"startTime":"0","endTime":"0","summary":"Given the large stake in the stock by institutions, Outlook Therapeutics' stock price might be vulnerable to their trading decisions. A total of 6 investors have a majority stake in the company with 52% ownership. Every investor in Outlook Therapeutics, Inc.  should be aware of the most powerful shareholder groups. The group holding the most number of shares in the company, around 30% to be precise, is institutions. In other words, the group stands to gain the most  from their investment into the company.Let's take a closer look to see what the different types of shareholders can tell us about Outlook Therapeutics.While studying institutional ownership for a company can add value to your research, it is also a good practice to research analyst recommendations to get a deeper understand of a stock's expected performance. There are a reasonable number of analysts covering the stock, so it might be useful to find out their aggregate view on the future.","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/d3vISzLZXw94x30FKv9beA--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/4d522452d0da08d8412701a84270533b","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/d3vISzLZXw94x30FKv9beA--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/4d522452d0da08d8412701a84270533b"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/owning-30-shares-institutional-owners-123255293.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["OTLK","BK4585",".IXIC","SQQQ","LU2210150020.SGD","IE00BGHQF748.EUR","IE00BKPKM429.USD","BK4112","QLD","BK4588","LU2210149790.SGD","QID","NQmain","MNQmain","PSQ","IE00B3QW5Z07.USD","BK4139","LU2095319765.USD","TQQQ","NDAQ","IE00B64PRP62.GBP"],"gpt_icon":1}],"pageSize":16,"totalPage":6,"pageCount":5,"totalSize":81}]}}