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PagerDuty, Inc.

15.56

-1.4300-8.42%

Post-market: 15.11-0.4500-2.89%19:57 EDT

Volume:2.51M

Turnover:39.53M

Market Cap:1.42B

PE:-26.29

High:16.59

Open:16.48

Low:15.37

Close:16.99

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Overview Company News Filings

Anaptys to Announce Top-line Data from Phase 2b Trial of Rosnilimab, a PD-1 Depleter and Agonist, in Rheumatoid Arthritis on Feb. 12, 2025

Supernus Pharmaceuticals to Host Conference Call and Webcast on February 25, 2025, to Discuss Fourth Quarter and Full Year 2024 Financial Results

Annovis to Present at Oppenheimer's 35th Annual Healthcare Life Sciences Conference

Gain Therapeutics CEO Gene Mack Issues Letter To Shareholders and Provides Operational Update

Coya Therapeutics Reports Statistically Significant Improvement of Inflammatory Blood Markers in Patients with Alzheimer’s Disease Following Monthly Dosing with Low-Dose IL-2, Further Supporting Clinical Development

TransCode Therapeutics Announces Completion of Cohort 3 Initial Dosing with Lead Candidate in Phase 1 Clinical Trial

Annovis Announces First Patients Entered into Pivotal Phase 3 Study of Buntanetap for Early Alzheimer’s Disease

Pasithea Therapeutics Announces Positive Safety Review Committee (SRC) Recommendation from its ongoing Phase 1 Clinical Trial of PAS-004 in Advanced Cancer

Supernus Announces FDA Approval of ONAPGO™ (apomorphine hydrochloride) for Parkinson’s Disease

Annovis Bio, Inc. Announces Pricing of $21 Million Public Offering

PLX: Revisiting the Thesis

Zacks Small Cap Research

Buy/Sell: Wall Street's Top 10 Stock Calls This Week

Annovis Bio, Inc. Announces Proposed Public Offering

BofA cuts rating on PagerDuty stock to 'underperform' on slowing growth

BofA Downgrades PagerDuty to Underperform, Price Target is $18

MT Newswires Live

Investors Aren't Buying PagerDuty, Inc.'s (NYSE:PD) Revenues

Simply Wall St.

Supernus Announces Label Update for Non-Stimulant ADHD Treatment, Qelbree®, Including New Pharmacodynamic Data and Information for Breastfeeding Women

Traws Pharma Announces Completion of Phase I Studies with Tivoxavir Marboxil, a Single Dose Oral Investigational Drug for the Treatment and Prevention of H5N1 Bird Flu

SAB BIO Announces R&D Webinar Event to Review Phase 1 Topline Results for SAB-142, a Disease-Modifying T1D Therapy

Vigil Neuroscience Reports Positive Data from its Phase 1 Clinical Trial Evaluating VG-3927 for the Potential Treatment of Alzheimer’s Disease

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We will also continue building upon the already extensive preclinical dossier for GT-02287 under the leadership of Joanne Taylor, Senior VP of Research, and Terenzio Ignoni, Senior VP of Technical Operations. Together, they will look to further characterize GT-02287’s mechanism of action and elucidate the broader neuroprotective role of GCase, suggested by the work of their respective teams, that goes beyond the lysosome to other cellular compartments including the endoplasmic reticulum and mitochondria. We have observed the stabilization of the mitochondria associated with administration of GT-02287 and its allosteric modulation","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/gain-therapeutics-ceo-gene-mack-134500386.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4023","BK4588","BK4585","LU1169590202.USD","GANX","GT","LU1169589451.USD","PD","BK4139","LENZ","BK4119"],"gpt_icon":0},{"id":"2509755202","title":"Coya Therapeutics Reports Statistically Significant Improvement of Inflammatory Blood Markers in Patients with Alzheimer’s Disease Following Monthly Dosing with Low-Dose IL-2, Further Supporting Clinical Development","url":"https://stock-news.laohu8.com/highlight/detail?id=2509755202","media":"Business Wire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509755202?lang=en_us&edition=fundamental","pubTime":"2025-02-06 21:00","pubTimestamp":1738846800,"startTime":"0","endTime":"0","summary":"Investigator-initiated data from Houston Methodist Hospital showed LD IL-2 reduced proinflammatory factors, both systemically and within the central nervous system, while demonstrating statistically significant improvement in beta amyloid 42 clearance with stabilization of cognitive decline over a five-month treatment period. 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In addition, patients receiving monthly LD IL-2 showed a 4.93-point improvemen","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/coya-therapeutics-reports-statistically-significant-130000484.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU1169590202.USD","COYA","CSF","LU1169589451.USD","LENZ","BK4023","PD","BK4139"],"gpt_icon":0},{"id":"2509273961","title":"TransCode Therapeutics Announces Completion of Cohort 3 Initial Dosing with Lead Candidate in Phase 1 Clinical Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2509273961","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509273961?lang=en_us&edition=fundamental","pubTime":"2025-02-06 21:00","pubTimestamp":1738846800,"startTime":"0","endTime":"0","summary":"PK data from Cohorts 1 and 2 consistent with preclinical and Phase 0 trial results. 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The Safety Review Committee monitoring the clinical trial unanimously approved opening of the third cohort based on its review of Cohort 1 and 2 safety and pharmacokinetic  data and is monitoring Cohort 3 as preliminary data becomes available.The dose administered to patients in the third cohort is approximately double the dose administered in the second cohort.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/transcode-therapeutics-announces-completion-cohort-130000434.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/transcode-therapeutics-announces-completion-cohort-130000434.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU1169589451.USD","BK4139","RNAZ","LU1169590202.USD","BK4539","BK4218","LENZ","PK","BK4023","PD","BK4181"],"gpt_icon":0},{"id":"2509285314","title":"Annovis Announces First Patients Entered into Pivotal Phase 3 Study of Buntanetap for Early Alzheimer’s Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2509285314","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509285314?lang=en_us&edition=fundamental","pubTime":"2025-02-05 21:00","pubTimestamp":1738760400,"startTime":"0","endTime":"0","summary":"MALVERN, Pa., Feb.  05, 2025  (GLOBE NEWSWIRE) -- via IBN – Annovis Bio Inc. (NYSE: ANVS) (\"Annovis\" or the \"Company\"), a late-stage clinical drug platform company pioneering transformative therapies ","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/02/05/3021101/0/en/Annovis-Announces-First-Patients-Entered-into-Pivotal-Phase-3-Study-of-Buntanetap-for-Early-Alzheimer-s-Disease.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0164881194.USD","LU0823039010.USD","LU0143863198.USD","LU0251143458.SGD","SG9999004220.SGD","ANVS","BK4548","BK4588","LU0261950470.USD","LU0181495838.USD","LU0531971678.HKD","IBN","BK4023","IE00B0JY6M65.USD","BK4207","BK4535","LU1868838027.USD","BK4523","LU0066902890.USD","LU0048575426.USD","LU0828237940.HKD","LU0264410563.USD","BK4585","LU1481012133.USD","LU0143863784.USD","LU0823038988.USD","IE00B7N09G41.SGD","LU1169590202.USD","BK4139","PD","IE00BYTNYM70.SGD","LU1102505762.USD","LU1169589451.USD","LU1102505929.USD","LU1868837565.USD","LU1868837722.USD"],"gpt_icon":0},{"id":"2509402104","title":"Pasithea Therapeutics Announces Positive Safety Review Committee (SRC) Recommendation from its ongoing Phase 1 Clinical Trial of PAS-004 in Advanced Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2509402104","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2509402104?lang=en_us&edition=fundamental","pubTime":"2025-02-05 19:59","pubTimestamp":1738756740,"startTime":"0","endTime":"0","summary":"SRC recommended that the trial escalate to the next dose level of 22mg capsule. “As we are observing substantial exposure levels of PAS-004, we remain encouraged by the safety profile PAS-004 continues to exhibit,” stated Dr. Tiago Reis Marques, Chief Executive Officer of Pasithea. “With the differentiated profile of PAS-004, we believe it is possible that this highly specific macrocyclic MEK inhibitor with a half life of greater than 60 hours may change the treatment paradigm for patients with NF1 and inoperable plexiform neurofibromas. We are looking forward to presenting updated pharmakokinetic  and pharmacodynamic  data during Q1 2025.”This press release contains statements that constitute “forward-looking statements” made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include statements regarding the Company’s ongoing Phase 1 clinical trial and the saf","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pasithea-therapeutics-announces-positive-safety-115900013.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4218","BK4181","PK","LENZ","BK4139","IE0031619046.USD","BK4135","SRC","CNS","LU1169590202.USD","IE00B66KJ199.SGD","IE00B19Z4B17.USD","BK4231","BK4080","BK4023","KTTA","IE00B7SZL793.SGD","LU1169589451.USD","BK4157","AE","BK4138","PD","KTTAW","AEIS"],"gpt_icon":1},{"id":"2508454681","title":"Supernus Announces FDA Approval of ONAPGO™ (apomorphine hydrochloride) for Parkinson’s Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2508454681","media":"GlobeNewswire","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508454681?lang=en_us&edition=fundamental","pubTime":"2025-02-04 22:00","pubTimestamp":1738677600,"startTime":"0","endTime":"0","summary":"ONAPGO is the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in adults with advanced Parkinson’s diseaseONAPGO is a wearable subcutaneous infusion devi","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/02/04/3020423/19871/en/Supernus-Announces-FDA-Approval-of-ONAPGO-apomorphine-hydrochloride-for-Parkinson-s-Disease.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1169590202.USD","CNS","LU1169589451.USD","ADHD","BK4135","BK4023","PD"],"gpt_icon":0},{"id":"2508311157","title":"Annovis Bio, Inc. 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(NYSE: ANVS) (“Annovis” or the “Company”), a late-stage clinical drug platform company pioneering transformative therapies","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/02/03/3019319/0/en/Annovis-Bio-Inc-Announces-Pricing-of-21-Million-Public-Offering.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"shareholding","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PD","LU0048575426.USD","LU0823038988.USD","IE00B0JY6M65.USD","IBN","ANVS","LU0828237940.HKD","LU1868837565.USD","LU1102505929.USD","LU0143863198.USD","LU0261950470.USD","BK4535","IE00B7N09G41.SGD","BK4523","SG9999004220.SGD","LU1102505762.USD","LU1868837722.USD","LU1169590202.USD","IE00BYTNYM70.SGD","LU0066902890.USD","BK4585","LU0181495838.USD","LU0143863784.USD","LU0531971678.HKD","BK4139","BK4207","BK4548","LU0164881194.USD","LU0823039010.USD","LU1169589451.USD","BK4588","LU1481012133.USD","LU0264410563.USD","LU0251143458.SGD","LU1868838027.USD","BK4023"],"gpt_icon":0},{"id":"2508494161","title":"PLX: Revisiting the Thesis","url":"https://stock-news.laohu8.com/highlight/detail?id=2508494161","media":"Zacks Small Cap Research","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508494161?lang=en_us&edition=fundamental","pubTime":"2025-02-03 17:38","pubTimestamp":1738575480,"startTime":"0","endTime":"0","summary":"Protalix Biotherapeutics, Inc.  finds itself in an enviable position as we begin 2025. The company has two approved products generating revenues and a pipeline with multiple candidates in development. Its products are produced and manufactured using the ProCellEx platform which uses a plant cell line rather than the usual mammalian one, to produce its therapeutic proteins. The company recently eliminated all debt from its balance sheet and holds over $27 million in cash on its balance sheet. We expect positive free cash flow generation over the next 12 months, which should strengthen the balance sheet even further.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/plx-revisiting-thesis-093800682.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","IE00BD4GTV84.USD","PEG","PLX","BK4208","BK4585","BK4218","BK4181","PK","BK4588","IE00BMG7P819.SGD","IE00BD4GTT62.SGD","IE00BMG7P926.USD","LU1169590202.USD","IE00BMG7P587.USD","BK4023","IE00BMG7P694.USD","PD","LU1169589451.USD","IE00BD4GTW91.USD"],"gpt_icon":0},{"id":"1168223665","title":"Buy/Sell: Wall Street's Top 10 Stock Calls This Week","url":"https://stock-news.laohu8.com/highlight/detail?id=1168223665","media":"the fly","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1168223665?lang=en_us&edition=fundamental","pubTime":"2025-02-02 09:57","pubTimestamp":1738461434,"startTime":"0","endTime":"0","summary":"Wall Street experts reveal the five stocks to buy, five stocks to sell this weekWhat has Wall Street been buzzing about this week?","market":"us","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://thefly.com/landingPageNews.php?id=4062051&headline=RIVN;META;QRVO;SWKS;CSCO;ADSK;EA;FND;PD;HSY;MLNK-BuySell-Wall-Streets-top--stock-calls-this-week&utm_source=https://thefly.com/&utm_medium=referral&utm_campaign=referral_traffic","is_publish_highlight":true,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"lsy1649979459173","symbols":["PD","EA","ADSK","QRVO","MLNK","RIVN","HSY","CSCO","FND","META"],"gpt_icon":1},{"id":"2508391426","title":"Annovis Bio, Inc. Announces Proposed Public Offering","url":"https://stock-news.laohu8.com/highlight/detail?id=2508391426","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508391426?lang=en_us&edition=fundamental","pubTime":"2025-02-01 09:14","pubTimestamp":1738372440,"startTime":"0","endTime":"0","summary":"MALVERN, Pa., Jan.  31, 2025  (GLOBE NEWSWIRE) -- via IBN – Annovis Bio, Inc. (NYSE: ANVS) (“Annovis” or the “Company”), a late-stage clinical drug platform company pioneering transformative therapies","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2025/02/01/3019065/0/en/Annovis-Bio-Inc-Announces-Proposed-Public-Offering.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["ANVS","LU0164881194.USD","LU0828237940.HKD","LU1868838027.USD","LU0066902890.USD","BK4588","IE00B0JY6M65.USD","LU1868837565.USD","LU0531971678.HKD","LU1868837722.USD","LU0143863784.USD","BK4523","LU0823039010.USD","BK4535","LU0251143458.SGD","LU0048575426.USD","LU1481012133.USD","BK4548","IE00BYTNYM70.SGD","BK4585","LU0823038988.USD","LU1169589451.USD","PD","IBN","LU0264410563.USD","LU1102505929.USD","LU1102505762.USD","BK4023","LU1169590202.USD","BK4207","IE00B7N09G41.SGD","BK4139","LU0181495838.USD","SG9999004220.SGD","LU0143863198.USD","LU0261950470.USD"],"gpt_icon":0},{"id":"2507624406","title":"BofA cuts rating on PagerDuty stock to 'underperform' on slowing growth","url":"https://stock-news.laohu8.com/highlight/detail?id=2507624406","media":"Investing.com","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507624406?lang=en_us&edition=fundamental","pubTime":"2025-01-30 23:02","pubTimestamp":1738249370,"startTime":"0","endTime":"0","summary":"Investing.com --Bank of America downgraded Pagerduty Inc  to \"Underperform\" from \"Buy\" on slowing revenue growth and rising competition in the incident management software space. The brokerage also lowered its price target to $18 from $23.BofA noted that PagerDuty’s core incident response revenue is growing at a slower pace, with annual recurring revenue rising just 4% in 2024 and expected to remain in the mid-single digits for fiscal 2025, which is well below the 29-33% growth seen in previous years.Competitive pressures, including Datadog’s On-Call product, could further weigh on its lower-tier small and mid-sized business customers, which account for 16% of revenue.While PagerDuty is expanding into AI-driven operations and customer service tools, BofA cautioned that these new offerings may not be as profitable as its core business and could limit further margin expansion.The new price target values PagerDuty at 3.2 times its estimated 2025 revenue, a discount to infrastructure softw","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/bofa-cuts-rating-pagerduty-stock-150250940.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PD","DDOG"],"gpt_icon":0},{"id":"2507647707","title":"BofA Downgrades PagerDuty to Underperform, Price Target is $18","url":"https://stock-news.laohu8.com/highlight/detail?id=2507647707","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507647707?lang=en_us&edition=fundamental","pubTime":"2025-01-30 20:41","pubTimestamp":1738240912,"startTime":"0","endTime":"0","summary":"PagerDuty (PD) has an average rating of hold and mean price target of $21.82, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major banks and ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["PD"],"gpt_icon":0},{"id":"2507661489","title":"Investors Aren't Buying PagerDuty, Inc.'s (NYSE:PD) Revenues","url":"https://stock-news.laohu8.com/highlight/detail?id=2507661489","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507661489?lang=en_us&edition=fundamental","pubTime":"2025-01-29 23:26","pubTimestamp":1738164396,"startTime":"0","endTime":"0","summary":"PagerDuty, Inc.'s ( NYSE:PD ) price-to-sales (or \"P/S\") ratio of 3.9x might make it look like a buy right now compared...","market":"sg","thumbnail":"https://images.simplywall.st/asset/industry/8041000-choice1-main-header/1585186668959","type":0,"news_type":0,"thumbnails":["https://images.simplywall.st/asset/industry/8041000-choice1-main-header/1585186668959"],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://simplywall.st/stocks/us/software/nyse-pd/pagerduty/news/investors-arent-buying-pagerduty-incs-nysepd-revenues","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"simplywall_highlight","symbols":["PD","ISBC","NYSE"],"gpt_icon":0},{"id":"2506743963","title":"Supernus Announces Label Update for Non-Stimulant ADHD Treatment, Qelbree®, Including New Pharmacodynamic Data and Information for Breastfeeding Women","url":"https://stock-news.laohu8.com/highlight/detail?id=2506743963","media":"GlobeNewswire","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2506743963?lang=en_us&edition=fundamental","pubTime":"2025-01-27 21:00","pubTimestamp":1737982800,"startTime":"0","endTime":"0","summary":"Updated label includes new data in Section 12.2, detailing serotonin 5-HT2C partial agonist activity and norepinephrine transporter inhibition, highlighting Qelbree’s multimodal pharmacodynamics. Qelbree is the first ADHD treatment to meet its post marketing requirement and receive labeling approval following the 2019 FDA guidance on Clinical Lactation Studies1. The update to include lactation data in the label  follows the 2019 FDA guidance suggesting lactation studies be conducted to inform breastfeeding with drug use recommendations and is based on a study involving 15 healthy lactating women.The study evaluated the secretion of viloxazine and its metabolite  into breast milk following a multi-dose  regimen of viloxazine. Results showed that the estimated daily infant dose  of viloxazine and 5-HVLX-gluc was 0.085 mg/kg and 0.00595 mg/kg, respectively, and the relative infant dose was approximately 1% and 0.07%, respectively, of the weight-normalized maternal daily dose  of viloxazin","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/supernus-announces-label-non-stimulant-130000268.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","ABVC","BK4135","SUPN","III","LU1169589451.USD","BK4134","BK4023","BK4007","PD","CNS","ADHD","LU1169590202.USD"],"gpt_icon":0},{"id":"2505948630","title":"Traws Pharma Announces Completion of Phase I Studies with Tivoxavir Marboxil, a Single Dose Oral Investigational Drug for the Treatment and Prevention of H5N1 Bird Flu","url":"https://stock-news.laohu8.com/highlight/detail?id=2505948630","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2505948630?lang=en_us&edition=fundamental","pubTime":"2025-01-23 20:00","pubTimestamp":1737633600,"startTime":"0","endTime":"0","summary":"Phase I completed in healthy volunteers with pharmacokinetic data supporting dosing for both therapeutic and further development for bird flu prevention. NEWTOWN, Pa., Jan. 23, 2025 /PRNewswire/ -- Traws Pharma, Inc.  , a clinical-stage biopharmaceutical company developing oral small molecule therapies for the treatment of respiratory viral diseases, today announced completion of Phase I clinical studies of its investigational one-dose influenza  therapy, tivoxavir marboxil , for the treatment or prevention of H5N1 bird flu.\"We believe that our clinical data in healthy volunteers support accelerated development of tivoxavir marboxil in response to the growing threat of bird flu,\" said Werner Cautreels, PhD, Chief Executive Officer of Traws Pharma.About Tivoxavir MarboxilSeasonal influenza represents an estimated multi-billion antiviral market opportunity, largely driven by global health organizations, practice guidelines and government tenders1, with upside potential from pandemic flu ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/traws-pharma-announces-completion-phase-120000809.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/traws-pharma-announces-completion-phase-120000809.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4218","CDC","BK4007","PK","LU1169590202.USD","TRAW","CEN","BK4181","BK4023","LU1169589451.USD","PD"],"gpt_icon":0},{"id":"2505831094","title":"SAB BIO Announces R&D Webinar Event to Review Phase 1 Topline Results for SAB-142, a Disease-Modifying T1D Therapy","url":"https://stock-news.laohu8.com/highlight/detail?id=2505831094","media":"GlobeNewswire","labels":["conferences","dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2505831094?lang=en_us&edition=fundamental","pubTime":"2025-01-23 20:00","pubTimestamp":1737633600,"startTime":"0","endTime":"0","summary":"Investor webinar scheduled Tuesday, January 28, 2025, at 8:00 AM EST. MIAMI, Jan. 23, 2025  -- SAB BIO , , a clinical-stage biopharmaceutical company with a novel immunotherapy platform that is developing human anti-thymocyte immunoglobulin  for delaying the onset or progression of type 1 diabetes , announced today that the Company will host a Research and Development webinar on January 28, 2025 to discuss the topline data for Phase 1 clinical trial for its lead candidate, SAB-142. The webinar will feature presentations from SAB BIO’s management team and T1D Key Opinion Leader  Michael Haller, MD, the division chief of the Pediatric Endocrinology Division at the University of Florida and Silverstein Family Eminent Scholar Chair in Pediatric Endocrinology.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/sab-bio-announces-r-d-120000937.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"conferences,dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4023","KOL","LU1169589451.USD","SABSW","LU1169590202.USD","PK","BIO","BK4588","PD","SABS","BK4585","BK4121","BK4218","BK4181"],"gpt_icon":0},{"id":"2505094867","title":"Vigil Neuroscience Reports Positive Data from its Phase 1 Clinical Trial Evaluating VG-3927 for the Potential Treatment of Alzheimer’s Disease","url":"https://stock-news.laohu8.com/highlight/detail?id=2505094867","media":"GlobeNewswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2505094867?lang=en_us&edition=fundamental","pubTime":"2025-01-23 20:00","pubTimestamp":1737633600,"startTime":"0","endTime":"0","summary":"- Safety, tolerability, pharmacokinetic, and pharmacodynamic profile supports continued development of VG-3927 as potential once-daily oral therapy for Alzheimer’s disease  -. - Robust and dose-dependent reductions of sTREM2 were achieved demonstrating sustained functional target engagement –。WATERTOWN, Mass., Jan. 23, 2025  -- Vigil Neuroscience, Inc. , a clinical-stage biotechnology company committed to harnessing the power of microglia for the treatment of neurodegenerative diseases, today announced positive data from its completed Phase 1 clinical trial evaluating VG-3927 for the potential treatment of AD. Collectively, the safety, tolerability, pharmacokinetic , and pharmacodynamic  profile supports the advancement of VG-3927 into a Phase 2 clinical trial as a potential once-daily oral therapy for AD.Achieved robust and dose-dependent reduction of sTREM2 of up to approximately 50% in the cerebral spinal fluid  demonstrating a strong PK/PD relationship, sustained target engagement 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