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AbbVie shares rose 1%.Pliant Therapeutics  shares fell 52% after it said it has ended its Beacon-IPF phase 2b trial of bexotegrast in idiopathic pulmonary fibrosis after an independent review found an imbalance in IPF-related adverse events between treatment and placebo groups.TG Therapeutics'  shares jumped past 18% after it reported Q4 net income of $0.15 per diluted share, swinging from a loss of $0.10 a year 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touches record low after scrapping trial of lung-disease drug","url":"https://stock-news.laohu8.com/highlight/detail?id=2516583396","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516583396?lang=en_us&edition=fundamental","pubTime":"2025-03-03 23:45","pubTimestamp":1741016711,"startTime":"0","endTime":"0","summary":"BUZZ-Pliant touches record low after scrapping trial of lung-disease drug  ** Shares of drug developer Pliant Therapeutics PLRX.O hit their lowest level on record at $1.59   ** The company discontinue","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250303:nL3N3PM14Y:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PLRX","BK4007"],"gpt_icon":0},{"id":"2516263088","title":"Pliant Therapeutics Ends Phase 2b Trial of Bexotegrast for Idiopathic Pulmonary Fibrosis; Shares Fall","url":"https://stock-news.laohu8.com/highlight/detail?id=2516263088","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516263088?lang=en_us&edition=fundamental","pubTime":"2025-03-03 23:20","pubTimestamp":1741015255,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics  shares were down almost 50% Monday after the company said it has ended its Beacon-IPF phase 2b trial of bexotegrast in idiopathic pulmonary fibrosis after an independent review found an imbalance in IPF-related adverse events between treatment and placebo groups.Despite this safety concern, early data showed efficacy on forced vital capacity, the company said.The study is the first late-stage IPF trial halted due to safety reasons while also demonstrating \"strong\" efficacy signals, it added.The percentage of IPF-related adverse events in the active groups was around 10%, similar to the phase 2a Integris-IPF trial; however, the placebo group in Beacon-IPF showed a lower adverse event rate, driving the observed imbalance, according to the company.Pliant Therapeutics said it will review the full dataset to better understand the benefit-risk profile and may plan new studies with lower doses for pulmonary fibrosis or other diseases, such as liver conditions.Price: 1.75,","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4007","BK4139","PLRX","LENZ"],"gpt_icon":0},{"id":"2516632651","title":"BRIEF-Pliant Therapeutics Provides Update On Beacon-IPF","url":"https://stock-news.laohu8.com/highlight/detail?id=2516632651","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516632651?lang=en_us&edition=fundamental","pubTime":"2025-03-03 22:50","pubTimestamp":1741013420,"startTime":"0","endTime":"0","summary":"BRIEF-Pliant Therapeutics Provides Update On Beacon-IPFMarch 3 (Reuters) - Pliant Therapeutics Inc PLRX.O:PLIANT THERAPEUTICS PROVIDES UPDATE ON BEACON-IPF, A PHASE 2B/3 TRIAL IN PATIENTS WITH IDIOPAT","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250303:nTUAB0YXYR:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PLRX","BK4007"],"gpt_icon":0},{"id":"2516371126","title":"Pliant Therapeutucs Shares Halted After Bexotegrast Phase 2b Trial Discontinued","url":"https://stock-news.laohu8.com/highlight/detail?id=2516371126","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516371126?lang=en_us&edition=fundamental","pubTime":"2025-03-03 22:47","pubTimestamp":1741013220,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics shares were halted in early morning trading after falling 25% to $2.57, after the company said it is discontinuing a phase 2b trial for bexotegrast in patients with idiopathic pulmonary fibrosis.The discontinuation follows a prespecified data review and recommendation by an independent Data Safety Monitoring Board, as well as a secondary review and recommendation by an outside expert panel.The late-stage biopharmaceutical company said that while an imbalance in unadjudicated IPF-related adverse events between the treatment and placebo groups led to the discontinuation of the trial, early evidence of efficacy on the forced vital capacity endpoint was also observed.Overall, the percentage of IPF-related adverse events in both dose groups was comparable--about 10%.The company plans to analyze the complete data from the trial and evaluate next steps for bexotegrast's development, including additional dose-ranging Phase 2b studies with lower doses in pulmonary fibrosis.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":"Pliant Therapeutucs Shares Halted After Bexotegrast Phase 2b Trial Discontinued","news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","PLRX"],"gpt_icon":0},{"id":"2516631123","title":"Pliant Therapeutics Inc - Committed to Development of Other Clinical Assets Including Pln-101095 in Oncology","url":"https://stock-news.laohu8.com/highlight/detail?id=2516631123","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516631123?lang=en_us&edition=fundamental","pubTime":"2025-03-03 22:27","pubTimestamp":1741012023,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250303:nTUAB0YXYR:4","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PLRX","BK4007"],"gpt_icon":0},{"id":"2516311406","title":"Pliant Therapeutics Inc - Discontinues Beacon-Ipf Phase 2B Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2516311406","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2516311406?lang=en_us&edition=fundamental","pubTime":"2025-03-03 22:27","pubTimestamp":1741012023,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250303:nTUAB0YXYR:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PLRX","BK4007"],"gpt_icon":0},{"id":"2512157055","title":"Blade Air Mobility Leads The Charge Among 3 US Penny Stocks","url":"https://stock-news.laohu8.com/highlight/detail?id=2512157055","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512157055?lang=en_us&edition=fundamental","pubTime":"2025-02-18 21:13","pubTimestamp":1739884425,"startTime":"0","endTime":"0","summary":"As the U.S. stock market flirts with record highs, investors are keenly watching for opportunities that may not be immediately apparent in the headlines. Penny stocks, often representing smaller or newer companies, continue to intrigue those looking beyond established giants for potential growth. Despite their historical reputation as speculative bets, some penny stocks today boast robust financial health and present intriguing possibilities for investors seeking unique opportunities.Get an in-depth perspective on Blade Air Mobility's performance by reading our balance sheet health report here.Gain insights into Blade Air Mobility's outlook and expected performance with our report on the company's earnings estimates.Overview: Nautilus Biotechnology, Inc. is a development stage life sciences company focused on creating platform technology to quantify and unlock the complexity of the proteome, with a market cap of $214.71 million.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/blade-air-mobility-leads-charge-131345868.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4213","BK4209","PVL","SB","BABB","BLDEW","BLDE","NAUT","PLRX","AIRI","BK4563","PHX","BK4021","BK4187"],"gpt_icon":0},{"id":"2512152624","title":"TD Cowen Keeps Their Buy Rating on Pliant Therapeutics (PLRX)","url":"https://stock-news.laohu8.com/highlight/detail?id=2512152624","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512152624?lang=en_us&edition=fundamental","pubTime":"2025-02-18 21:06","pubTimestamp":1739883998,"startTime":"0","endTime":"0","summary":"TD Cowen analyst Ritu Baral maintained a Buy rating on Pliant Therapeutics (PLRX – Research Report) today. The company’s shares closed last Friday ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/td-cowen-keeps-their-buy-rating-on-pliant-therapeutics-plrx?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/td-cowen-keeps-their-buy-rating-on-pliant-therapeutics-plrx?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PLRX","COWN","TD"],"gpt_icon":0},{"id":"2512911522","title":"Positive Outlook on Pliant Therapeutics Despite Trial Uncertainty","url":"https://stock-news.laohu8.com/highlight/detail?id=2512911522","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2512911522?lang=en_us&edition=fundamental","pubTime":"2025-02-17 16:15","pubTimestamp":1739780155,"startTime":"0","endTime":"0","summary":"Leerink Partners analyst Faisal Khurshid has maintained their bullish stance on PLRX stock, giving a Buy rating on February 13. Faisal Khurshid has...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/positive-outlook-on-pliant-therapeutics-despite-trial-uncertainty?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/positive-outlook-on-pliant-therapeutics-despite-trial-uncertainty?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PLRX","LENZ","BK4007","BK4139"],"gpt_icon":0},{"id":"2511468056","title":"All You Need to Know About PLIANT THERAPT (PLRX) Rating Upgrade to Buy","url":"https://stock-news.laohu8.com/highlight/detail?id=2511468056","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511468056?lang=en_us&edition=fundamental","pubTime":"2025-02-15 01:00","pubTimestamp":1739552412,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics, Inc.  could be a solid choice for investors given its recent upgrade to a Zacks Rank #2 . This rating change essentially reflects an upward trend in earnings estimates -- one of the most powerful forces impacting stock prices.A company's changing earnings picture is at the core of the Zacks rating. The system tracks the Zacks Consensus Estimate -- the consensus measure of EPS estimates from the sell-side analysts covering the stock -- for the current and following years.Individual investors often find it hard to make decisions based on rating upgrades by Wall Street analysts, since these are mostly driven by subjective factors that are hard to see and measure in real time. In these situations, the Zacks rating system comes in handy because of the power of a changing earnings picture in determining near-term stock price movements.Therefore, the Zacks rating upgrade for PLIANT THERAPT basically reflects positivity about its earnings outlook that could translate into ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/know-pliant-therapt-plrx-rating-170012800.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["PLRX"],"gpt_icon":1},{"id":"2511666697","title":"Pliant Therapeutics Price Target Maintained With a $10.00/Share by Needham","url":"https://stock-news.laohu8.com/highlight/detail?id=2511666697","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511666697?lang=en_us&edition=fundamental","pubTime":"2025-02-14 19:01","pubTimestamp":1739530860,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/PLRX/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 14, 2025 06:01 ET (11:01 GMT)","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["PLRX","LENZ"],"gpt_icon":0},{"id":"2511311579","title":"Sector Update: Health Care Stocks Mixed Thursday Afternoon","url":"https://stock-news.laohu8.com/highlight/detail?id=2511311579","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511311579?lang=en_us&edition=fundamental","pubTime":"2025-02-14 03:02","pubTimestamp":1739473343,"startTime":"0","endTime":"0","summary":"Health care stocks were mixed Thursday afternoon with the NYSE Health Care Index easing 0.1% and the Health Care Select Sector SPDR Fund  increasing 0.1%.The iShares Biotechnology ETF  rose 0.6%.In sector news, the US Senate confirmed Robert F. Kennedy Jr. as head of the US Department of Health and Human Services.In corporate news, Pliant Therapeutics'  shares surged 25% after the company started assembling an external expert panel to evaluate unblinded data from the phase 2b trial of bexotegrast in people with idiopathic pulmonary fibrosis.GE Healthcare Technologies  shares jumped 9.3% after the company reported higher Q4 adjusted earnings and revenue.Aardvark Therapeutics  shares debuted on Nasdaq with an opening price of $15.18, below the initial public offering price of $16. The stock fell 20% in recent trading.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4007","IBB","XLV","GEHC","LU0689626769.HKD","BK4585","PLRX","LU0124676726.USD","BK4588","BK4082","BK4581","AARD"],"gpt_icon":0},{"id":"2511575923","title":"Optimistic Buy Recommendation Amid Pliant Therapeutics’ Trial Review and Stock Surge","url":"https://stock-news.laohu8.com/highlight/detail?id=2511575923","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511575923?lang=en_us&edition=fundamental","pubTime":"2025-02-14 02:15","pubTimestamp":1739470516,"startTime":"0","endTime":"0","summary":"Analyst Joseph Stringer from Needham maintained a Buy rating on Pliant Therapeutics (PLRX – Research Report) and keeping the price target at $10.00...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/optimistic-buy-recommendation-amid-pliant-therapeutics-trial-review-and-stock-surge?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/optimistic-buy-recommendation-amid-pliant-therapeutics-trial-review-and-stock-surge?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4007","LENZ","PLRX","BK4139"],"gpt_icon":0},{"id":"2511527645","title":"Pliant Therapeutics to Assemble Expert Panel to Review BEACON-IPF Trial Data; Shares Jump","url":"https://stock-news.laohu8.com/highlight/detail?id=2511527645","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511527645?lang=en_us&edition=fundamental","pubTime":"2025-02-14 00:15","pubTimestamp":1739463356,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics'  shares rose by than 32% in recent Thursday trading after the company said it has begun assembling an external expert panel to evaluate unblinded data from the ongoing BEACON-IPF Phase 2b trial of bexotegrast in patients with idiopathic pulmonary fibrosis.This move comes after the trial's independent Data Safety Monitoring Board recommended pausing enrollment and dosing, the company said, adding that it has been unable to identify the rationale behind the DSMB's recommendation after reviewing blinded data.The panel, consisting of pulmonary disease and biostatistics experts, will offer an independent recommendation and later collaborate with an expanded DSMB to reach a consensus on BEACON-IPF. The process is expected to conclude in 2 to 4 weeks.Following the DSMB's recommendation, Pliant voluntarily paused enrollment and dosing in the BEACON-IPF trial while remaining blinded to preserve data integrity of the BEACON-IPF 2b and its potential as a registrational study,","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4007","BK4139","PLRX","LENZ"],"gpt_icon":0},{"id":"2511521154","title":"Pliant Therapeutics Shares Rise After Board Recommendations for Bexotegrast","url":"https://stock-news.laohu8.com/highlight/detail?id=2511521154","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511521154?lang=en_us&edition=fundamental","pubTime":"2025-02-13 23:27","pubTimestamp":1739460420,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics shares were up 23% to $3.34 after the company said an independent Data Safety Monitoring Board is allowing it to begin the assembly of an outside expert panel to review unblinded data from an ongoing Phase 2b trial of bexotegrast in patients with idiopathic pulmonary fibrosis.The biopharmaceutical company said the panel, consisting of experts in pulmonary diseases and biostatistics, will provide an independent recommendation to Pliant regarding the trial.The panel will serve as part of an expanded DSMB with the goal to reach a consensus recommendation regarding the trial. The decision to assemble the outside panel was taken as the company hasn't been able, through review of blinded data, to determine the rationale for the DSMB's recommendation to pause enrollment and dosing in the trial.Pliant expects this process to conclude in two to four weeks.Following the DSMB's previously announced recommendation, Pliant voluntarily paused enrollment and dosing in the clinical","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","BK4139","PLRX","LENZ"],"gpt_icon":1}],"pageSize":16,"totalPage":5,"pageCount":2,"totalSize":80}]}}