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Wainwright Cuts to Neutral Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2510853993","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510853993?lang=en_us&edition=fundamental","pubTime":"2025-02-10 19:40","pubTimestamp":1739187654,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250210:nFWN3P10LF:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PLRX","BK4007"],"gpt_icon":0},{"id":"2510535668","title":"Pliant Therapeutics Shares Fall on Drug Trial Pause After Safety Board Review","url":"https://stock-news.laohu8.com/highlight/detail?id=2510535668","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510535668?lang=en_us&edition=fundamental","pubTime":"2025-02-10 19:28","pubTimestamp":1739186880,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics shares fell sharply in pre-market trading Monday after it said it would pause its pulmonary fibrosis drug following a review by independent monitors.Shares traded 55% lower ahead of the morning bell at $3.51.The clinical stage biopharmaceutical company said Friday it decided to pause the Beacon-IPF phase 2b trial of bexotegrast after a prespecified data review and recommendations by the trial's independent Data Safety Monitoring Board.The drug is a treatment for idiopathic pulmonary fibrosis, a common type of pulmonary fibrosis which is characterized by scarring of the lungs but in particular, where the scarring is of unknown cause.The pause means that the company won't enroll anymore patients to the study and will also halt dosing for the time being.Pliant said that it will review the data to understand the monitoring board's rationale for their recommendation. It has also informed clinical trial investigators and is in the process of informing global regulatory au","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4007","BK4139","PLRX","LENZ"],"gpt_icon":0},{"id":"2510583108","title":"RBC Downgrades Pliant Therapeutics to Sector Perform From Outperform, Cuts Price Target to $4 From $45, Keeps Speculative Risk","url":"https://stock-news.laohu8.com/highlight/detail?id=2510583108","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510583108?lang=en_us&edition=fundamental","pubTime":"2025-02-10 19:17","pubTimestamp":1739186249,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics (PLRX) has an average rating of overweight and mean price target of $36, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from m","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate","earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["PLRX","LENZ"],"gpt_icon":0},{"id":"2510832836","title":"Pliant Therapeutics Inc : RBC Cuts to Sector Perform From Outperform","url":"https://stock-news.laohu8.com/highlight/detail?id=2510832836","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510832836?lang=en_us&edition=fundamental","pubTime":"2025-02-10 18:20","pubTimestamp":1739182802,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250210:nFWN3P10CQ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["PLRX","BK4007"],"gpt_icon":0},{"id":"2510834454","title":"Pliant Therapeutics Suspends Enrollment in Phase 2b Idiopathic Pulmonary Fibrosis Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2510834454","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2510834454?lang=en_us&edition=fundamental","pubTime":"2025-02-10 18:08","pubTimestamp":1739182090,"startTime":"0","endTime":"0","summary":"Pliant Therapeutics  said late Friday it has suspended enrollment and treatment in a phase 2b trial of bexotegrast for idiopathic pulmonary fibrosis following a recommendation from the trial's data safety monitoring board.The company said it is analyzing data to better understand the board's reasoning.\"Blinding of the study will be maintained to preserve trial integrity,\" Pliant Therapeutics said.The company's shares were down 54% in Monday premarket 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07:19","pubTimestamp":1738970370,"startTime":"0","endTime":"0","summary":"BUZZ-Pliant pauses enrollment for lung disease treatment trial** Shares of drug developer Pliant Therapeutics PLRX.O fall 65.5% to $2.72 in extended trading** Company says a mid-stage trial testing experimental drug bexotegrast in patients with idiopathic pulmonary fibrosis has been paused ** Says enrollment and dosing has been paused while a Data Safety Monitoring Board  reviews its trial data** A DSMB refers to an independent group of experts that reviews clinical trial data to ensure the safety of participants and the validity of the trial** Idiopathic pulmonary fibrosis is a chronic lung disease that causes scarring and stiffening of the lung tissue** Up to last close, stock down 40.9% YTD  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Therapeutics (PLRX) trading resumes Published first on TheFly – the ultimate source for real-time, market-moving breaking financia...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/pliant-therapeutics-trading-resumes?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/pliant-therapeutics-trading-resumes?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4007","PLRX","LENZ"],"gpt_icon":0},{"id":"2509720407","title":"Pliant Therapeutics pauses enrollment, dosing in BEACON-IPF Phase 2b 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Monitorin...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/pliant-therapeutics-pauses-enrollment-dosing-in-beacon-ipf-phase-2b-trial?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/pliant-therapeutics-pauses-enrollment-dosing-in-beacon-ipf-phase-2b-trial?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["PLRX","BK4139","BK4007","LENZ"],"gpt_icon":0},{"id":"2509726917","title":"BRIEF-Pliant Therapeutics Provides Update On BEACON-IPF, A Phase 2B/3 Trial In Patients With Idiopathic Pulmonary 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