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8 PRs out of 27 evaluable heavily pre-treated  MTAP-deletion UC and NSCLC patients. 9 of 9 responses have confirmed by RECIST 1.1 . MTAP-deletion UC: 40%  confirmed ORR and 3 pts on treatment >250 days. MTAP-deletion SqNSCLC: ~38%  confirmed ORR and 4 pts on treatment >200 days. Multiple PRs with genetic co-alterations, including MTAP-deletion and KRAS G12D mutation in NSCLC, and MTAP-deletion and FGFR-TACC3 fusion in UC. Median DOT not yet reached and >6.2 months, and median TTR ~2.7 months. Targeting expansion of Phase 1/2 study of IDE397 in combination with Trodelvy in MTAP-deletion UC in Q4 2024; patient case study of PR by RECIST 1.1 and rapid >95% ctDNA reduction of combination will be presented at ENA 2024. IDE397 demonstrated deep and durable regressions in combination with PRMT5 inhibitors BMS-986504 and AMG 193 in preclinical models. \"The clinical data update from the late breaker oral presentation at ENA 2024 provides further clinical proof-of-","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/KpavzFXG.KOmjdIMYuZXbA--~B/aD0yNjM7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/74efd2e2f7cc28d3a6ce5efb40fb6e7d","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/KpavzFXG.KOmjdIMYuZXbA--~B/aD0yNjM7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/74efd2e2f7cc28d3a6ce5efb40fb6e7d"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/ideaya-announces-positive-interim-phase-100000393.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/ideaya-announces-positive-interim-phase-100000393.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["QD","NCI","BK4121","BK4166","CR","IDYA","BK4161","BK4202","BK4503","BK4563","BK4139","BK4138","SD","AE","SEER","BK4213"],"gpt_icon":0},{"id":"2478677865","title":"Revolution Medicines Presents Initial Data from RMC-9805 Monotherapy Study in Patients with Advanced Pancreatic Ductal Adenocarcinoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2478677865","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2478677865?lang=en_us&edition=fundamental","pubTime":"2024-10-25 16:15","pubTimestamp":1729844100,"startTime":"0","endTime":"0","summary":"First clinical results for RMC-9805, a RAS(ON) G12D-selective inhibitor, demonstrate encouraging tolerability and antitumor activity in patients with PDAC Investor webcast to be held Friday, October 2","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/10/25/2969288/0/en/Revolution-Medicines-Presents-Initial-Data-from-RMC-9805-Monotherapy-Study-in-Patients-with-Advanced-Pancreatic-Ductal-Adenocarcinoma.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4157","BK4503","IE00BD6J9T35.USD","LU1720051108.HKD","BK4585","LU1854104046.USD","BK4141","LU1861215975.USD","LU2298322129.HKD","IE00B7SZL793.SGD","ON","IE00BZ199S13.USD","LU0348723411.USD","LU2360107325.USD","LU1861220033.SGD","BK4166","LU0124384867.USD","LU2357305700.SGD","IE00B66KJ199.SGD","BK4139","BK4590","LU0724618433.USD","BK4581","LU1548497426.USD","LU1720051017.SGD","LU1854103824.USD","LU1861219969.SGD","BK4561","QD","BK4512","BK4144","LU1978683503.SGD","IE0031619046.USD","IE00B19Z4B17.USD","RVMD","ET","LU1861214812.USD","BK4563","MDCO","AEIS","BK4588"],"gpt_icon":0},{"id":"2478411697","title":"Tyra Biosciences Reports Interim Clinical Proof-of-Concept Data for TYRA-300, an Investigational Oral FGFR3-Selective Inhibitor, in Phase 1/2 SURF301 Study in Patients with Metastatic Urothelial Cancer (mUC)","url":"https://stock-news.laohu8.com/highlight/detail?id=2478411697","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2478411697?lang=en_us&edition=fundamental","pubTime":"2024-10-25 06:05","pubTimestamp":1729807500,"startTime":"0","endTime":"0","summary":"- Encouraging preliminary anti-tumor activity observed in heavily pre-treated population -. - At ≥ 90 mg QD, 6 out of 11  patients with FGFR3+ mUC achieved a confirmed partial response , with 100% disease control rate and sustained duration of activity -. - Positive safety results across all QD doses, with infrequent FGFR2/FGFR1-associated toxicities -. - Conference call scheduled for October 25th, 2024, at 8AM EDT -. CARLSBAD, Calif., Oct. 24, 2024 /PRNewswire/ -- Tyra Biosciences, Inc. , a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor  biology, announced today clinical proof-of-concept data for TYRA-300 in patients with metastatic urothelial  cancer from its ongoing SURF301 Phase 1/2 study. These data will be presented in a late-breaking oral presentation at the 36th EORTC-NCI-AACR  Symposium on Molecular Targets and Cancer Therapeutics, being held October 23-25, 2024","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/14NqX0.RJgyZke145_EJTw--~B/aD0xNjQ7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/38a561c6850218e47560162fca1bdb04","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/14NqX0.RJgyZke145_EJTw--~B/aD0xNjQ7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/38a561c6850218e47560162fca1bdb04"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/tyra-biosciences-reports-interim-clinical-220500412.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/tyra-biosciences-reports-interim-clinical-220500412.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["TYRA","BK4213","BK4139","QD","BK4183","LU1878469433.USD","PACI.U","BK4563","ODD","BK4503","BK4097","RPD","BK4166","TRAE","PR"],"gpt_icon":0},{"id":"2477309998","title":"Revolution Medicines Presents Updated Data from RMC-6236 Monotherapy Study in Patients with Advanced Pancreatic Ductal Adenocarcinoma","url":"https://stock-news.laohu8.com/highlight/detail?id=2477309998","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2477309998?lang=en_us&edition=fundamental","pubTime":"2024-10-23 18:00","pubTimestamp":1729677600,"startTime":"0","endTime":"0","summary":"Safety findings consistent with previously reported data, no new safety signals observed. Investor webcast to be held Friday, October 25 at 12:00 p.m. Eastern Time . “The maturing data reported today continue to solidify the compelling progression-free survival and overall survival for patients with pancreatic cancer treated with RMC-6236, our oral RAS multi-selective inhibitor, in the Phase 1 study,” said Mark A. Goldsmith, M.D., Ph.D., chief executive officer and chairman of Revolution Medicines. “These results support our ongoing Phase 3 registrational study, RASolute 302, and our belief that RMC-6236 monotherapy could potentially become an important therapeutic option for patients living with advanced or metastatic pancreatic cancer.”RMC-6236 demonstrated durable antitumor activity as evidenced by updated progression-free survival  and overall survival  at daily doses ranging from 160 mg to 300 mg, as described below. Patients with PDAC harboring a KRAS G12X mutation in the second-","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/mONgtKYbT.aDZPHhJadxUg--~B/aD02NDE7dz0yMDgxO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/globenewswire.com/c39d32b4c3f69d5f9c483b0895061001","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/mONgtKYbT.aDZPHhJadxUg--~B/aD02NDE7dz0yMDgxO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/globenewswire.com/c39d32b4c3f69d5f9c483b0895061001"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/revolution-medicines-presents-updated-data-100000615.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU1854104046.USD","LU0266512127.USD","BK4157","IE00B19Z4B17.USD","MDCO","IE0031619046.USD","OS","BK4139","LU0058720904.USD","LU1059921491.USD","LU0868494617.USD","CI","AEIS","LU0124384867.USD","LU1854103824.USD","LU0456854461.SGD","ON","LU1861214812.USD","CRC","BK4141","BK4503","LU1720051017.SGD","BK4581","BK4561","NE","RVMDW","LU1261432733.SGD","BK4563","IE00BZ199S13.USD","PFS","LU1548497426.USD","LU2360107325.USD","LU1861215975.USD","BK4512","LU1978683503.SGD","QD","BK4144","IE00B66KJ199.SGD","IE00B7SZLL34.SGD","IE00B7SZL793.SGD","RVMD","BK4196","BK4211","ET","BK4166","IE00BD6J9T35.USD","LU0724618433.USD","IE00BSNM7G36.USD","LU2357305700.SGD","IE00B19Z3B42.SGD","BK4195"],"gpt_icon":0},{"id":"2477406331","title":"Oncternal Therapeutics Announces Updated Safety and Efficacy Data for Phase 1/2 Study of ONCT-534 for the Treatment of R/R Metastatic Castration-Resistant Prostate Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2477406331","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2477406331?lang=en_us&edition=fundamental","pubTime":"2024-10-22 21:00","pubTimestamp":1729602000,"startTime":"0","endTime":"0","summary":"SAN DIEGO, Oct.  22, 2024  (GLOBE NEWSWIRE) -- Oncternal Therapeutics, Inc. (Nasdaq: ONCT) (the “Company”) today announced updated data from its Phase 1/2 Study of ONCT-534 for the treatment of patien","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/10/22/2967000/0/en/Oncternal-Therapeutics-Announces-Updated-Safety-and-Efficacy-Data-for-Phase-1-2-Study-of-ONCT-534-for-the-Treatment-of-R-R-Metastatic-Castration-Resistant-Prostate-Cancer.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4166","ONCT","QD","AR","BK4503","BK4139","PFS","BK4563","BK4213","BK4195","BK4211"],"gpt_icon":0},{"id":"2477784895","title":"Discover 3 US Penny Stocks With Market Caps Over $70M","url":"https://stock-news.laohu8.com/highlight/detail?id=2477784895","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2477784895?lang=en_us&edition=fundamental","pubTime":"2024-10-22 06:04","pubTimestamp":1729548287,"startTime":"0","endTime":"0","summary":"As of October 2024, the U.S. stock market is experiencing mixed movements with the S&P 500 and Dow Jones Industrial Average pulling back from record highs, while the Nasdaq Composite continues to rise driven by strong performances in technology stocks like Nvidia. For investors eyeing opportunities beyond large-cap stocks, penny stocks—despite their somewhat outdated label—remain a relevant investment area, especially when they are backed by solid financial health. These smaller or newer companies can offer unique growth potential and affordability; let's examine several penny stocks that stand out for their financial strength in today's market landscape.Take a closer look at FTC Solar's potential here in our financial health report.Gain insights into FTC Solar's outlook and expected performance with our report on the company's earnings estimates.","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/NPWPwaqd_YNMPuUbekamwQ--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/17286ad821a1799fbe520d67c5c5f1ea","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/NPWPwaqd_YNMPuUbekamwQ--~B/aD00MzI7dz0xMTk0O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/simply_wall_st__316/17286ad821a1799fbe520d67c5c5f1ea"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/discover-3-us-penny-stocks-220447345.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4585","DFS","LU1861217088.USD","BK4563","BABB","BK4143","QD","PVL","LU0106831901.USD","FTCI","BK4551","RLX","BK4526","BK4096","BK4209","LU1668664300.SGD","BK4503","ARC","SES","LU2360107671.USD","LU1861220207.SGD","BK4213","BK4588","LU1791807156.HKD","BK4075","BK4166","BK4539"],"gpt_icon":1},{"id":"2475608932","title":"HUTCHMED Announces that TAGRISSO® plus ORPATHYS® demonstrated high, clinically meaningful response rate in lung cancer patients with high levels of MET overexpression and/or amplification in SAVANNAH Phase II trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2475608932","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2475608932?lang=en_us&edition=fundamental","pubTime":"2024-10-16 12:30","pubTimestamp":1729053000,"startTime":"0","endTime":"0","summary":"—New data demonstrate efficacy for the oral treatment combination to address MET-driven resistance in EGFR-mutated lung cancer— —MET is a common biomarker in this setting for patients who develop resi","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/10/16/2963756/0/en/HUTCHMED-Announces-that-TAGRISSO-plus-ORPATHYS-demonstrated-high-clinically-meaningful-response-rate-in-lung-cancer-patients-with-high-levels-of-MET-overexpression-and-or-amplifica.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4585","BK4563","LU1496350502.SGD","QD","00013","CNS","BK1587","BK4503","MET","LU1989772840.SGD","BK4135","BK1191","BK1588","LU1291159041.SGD","BK4162","BK4588","LU1989771016.USD","BK4156","LU1989772923.USD","BK4166"],"gpt_icon":0},{"id":"2474742794","title":"Asian Equities Traded in the US as American Depositary Receipts Decline in Thursday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2474742794","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2474742794?lang=en_us&edition=fundamental","pubTime":"2024-10-10 22:43","pubTimestamp":1728571401,"startTime":"0","endTime":"0","summary":"Asian equities traded in the US as American depositary receipts were moving modestly lower Thursday morning, declining 0.26% to 2,111.40 on the S&P Asia 50 ADR Index.From North Asia, the gainers were led by financial services company CNFinance  and property technology company Fangdd Network Group , which climbed 6.8% and 6.2% respectively. They were followed by online game developer The9  and consumer lending firm Qudian , which rose 3.6% and 2.7% respectively.The decliners from North Asia were led by mobile big data platform Aurora Mobile  and fintech firm AMTD Digital , which fell 8.3% and 6.3% respectively. They were followed by game live-streaming platform HUYA  and solar panel maker JinkoSolar , which dropped 5.2% and 4.4% respectively.From South Asia, the only gainers were IT firm Sify Technologies  and financial services company HDFC Bank , which increased 8.9% and 1.4% respectively.The decliners from South Asia were led by IT firms Infosys  and Wipro , which lost 3.4% and 2.9% ","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["LU0791590937.USD","SIFY","RDY.AU","BK4585","WIT","BK4107","LU0231203729.USD","BK4141","HKD","LU0012050646.USD","LU0197229882.USD","IE00B7SZL793.SGD","JG","DUO","IE00B7N09G41.SGD","NCTY","LU0898667661.SGD","BK4166","LU0333810181.USD","LU0918141705.HKD","CNF","LU1559883803.SGD","SG9999014021.USD","LU0390134368.USD","BK4531","LU1366334578.USD","AFG","LU2045819591.USD","WNS","LU0348744763.USD","JKS","LU0862451753.SGD","QD","LU1805238398.USD","HUYA","IE00B19Z4B17.USD","BK4085","BK4513","LU1267930656.SGD","BK4195","LU0890818403.SGD","BK4563","BK4226","LU2087589342.USD","HDB","LU0066902890.USD","INFY","LU1169590202.USD","RDY","BK4588"],"gpt_icon":1},{"id":"2472896507","title":"Asian Equities Traded in the US as American Depositary Receipts Rise Sharply in Friday Trading","url":"https://stock-news.laohu8.com/highlight/detail?id=2472896507","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2472896507?lang=en_us&edition=fundamental","pubTime":"2024-10-04 22:52","pubTimestamp":1728053557,"startTime":"0","endTime":"0","summary":"Asian equities traded in the US as American depositary receipts were moving sharply higher Friday morning, rising 1.17% to 2,157.49 on the S&P Asia 50 ADR Index. With the rally, the index is poised to end the week up about 1.3%.From North Asia, the gainers were led by consumer lending firm LexinFintech  and solar panel maker JinkoSolar , which climbed 13% and 10% respectively. Mobile big data platform Aurora Mobile  was up 8.7% and online brokerage UP Fintech  added 7.7%.The decliners from North Asia were led by fintech firm AMTD Digital  and consumer lending company Qudian , which fell 11% and 4.3%, respectively. They were followed by electric vehicle maker NIO  and video-sharing platform Bilibili , which retreated 3.4% and 2.3%, respectively.From South Asia, the gainers were led by IT firms Infosys  and Wipro , which rose 1.5% and 1.2%, respectively. They were followed by business process management company WNS  and financial services company HDFC Bank , which were up 1.1% and 0.7%, ","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["SG9999014021.USD","BK4510","LU0890818403.SGD","09866","IE00B7SZL793.SGD","INFY","BK4504","RDY","TIGR","IE00BYTNYM70.SGD","SIFY","LU0348816934.USD","JG","BK4566","LU1267930656.SGD","JKS","BK4007","NIO","HKD","RDY.AU","BK4503","BK4554","WNS","NIO.SI","AFG","EVS.SI","IE00B3M56506.USD","BK4099","IE00B7N09G41.SGD","BK4519","LU1804176565.USD","LU0066902890.USD","LX","LU0791591158.USD","TLK","WIT","NQGM","BK4548","LU0708995583.HKD","HDB","IE00B66KJ199.SGD","LU1105468828.SGD","LU0531971678.HKD","LU0791590937.USD","IE00B19Z4B17.USD","BK4509","LU0320764599.SGD","BILI","LU0431992006.USD","QD"],"gpt_icon":1},{"id":"2470504751","title":"Enliven Therapeutics Announces Positive Data Update from Phase 1 Clinical Trial of ELVN-001 in Chronic Myeloid Leukemia","url":"https://stock-news.laohu8.com/highlight/detail?id=2470504751","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470504751?lang=en_us&edition=fundamental","pubTime":"2024-09-28 21:35","pubTimestamp":1727530500,"startTime":"0","endTime":"0","summary":"Updated Phase 1 data presented at ESH-iCMLf 26th Annual John Goldman Conference Reported cumulative MMR rate of 44% (8/18) by 24 weeks, with stable or deepening responses between weeks 12 and 24, whic","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/09/28/2954762/0/en/Enliven-Therapeutics-Announces-Positive-Data-Update-from-Phase-1-Clinical-Trial-of-ELVN-001-in-Chronic-Myeloid-Leukemia.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","ELVN","BK4007","BK4166","BK4503","TRAE","QD","BK4139","BK4563"],"gpt_icon":0},{"id":"2470781135","title":"Pasithea Therapeutics Announces Positive Initial Safety, Tolerability, Pharmacokinetic (PK), and Preliminary Efficacy Data from its Phase 1 Clinical Trial of PAS-004 in Advanced Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2470781135","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470781135?lang=en_us&edition=fundamental","pubTime":"2024-09-26 19:02","pubTimestamp":1727348520,"startTime":"0","endTime":"0","summary":"-- Single patient in 2mg cohort with stage 3 colon cancer who received 4 prior lines of therapy achieves prolonged stable disease and remains on drug into 6th dosing cycle -- -- No treatment-related a","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/09/26/2953686/0/en/Pasithea-Therapeutics-Announces-Positive-Initial-Safety-Tolerability-Pharmacokinetic-PK-and-Preliminary-Efficacy-Data-from-its-Phase-1-Clinical-Trial-of-PAS-004-in-Advanced-Cancer.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4139","QD","BK4181","PK","BK4157","BK4563","IE0031619046.USD","CNS","IE00B66KJ199.SGD","IE00B7SZL793.SGD","LU1169589451.USD","LU1169590202.USD","BK4503","BK4135","KTTA","PD","IE00B19Z4B17.USD","BK4218","AEIS","LENZ","BK4023","BK4166"],"gpt_icon":0},{"id":"2470785672","title":"Enanta Pharmaceuticals Announces Positive Topline Results for EDP-323 in a Phase 2a Human Challenge Study of Healthy Adults Infected With Respiratory Syncytial Virus (RSV)","url":"https://stock-news.laohu8.com/highlight/detail?id=2470785672","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2470785672?lang=en_us&edition=fundamental","pubTime":"2024-09-26 18:00","pubTimestamp":1727344800,"startTime":"0","endTime":"0","summary":"Treatment With Once-Daily EDP-323 Met Primary and Secondary Endpoints, Achieving Highly Statistically Significant Reductions in Both Viral Load and Clinical Symptoms Compared to Placebo. Conference Call and Webcast to Discuss Data at 8:30 a.m. ET Today. \"We are excited about these impressive data that demonstrate a rapid and sustained reduction in viral load. These results are among the strongest ever reported in an RSV challenge study, raising the high bar set by zelicapavir. The significant antiviral activity and symptom alleviation observed in this study highlight EDP-323’s potential as a safe, highly effective, direct-acting antiviral for the treatment of RSV,\" said Scott T. Rottinghaus, M.D., Chief Medical Officer of Enanta Pharmaceuticals.This Phase 2a study was a randomized, double-blind, placebo-controlled, human challenge study of 142 healthy adult participants inoculated with RSV. Randomized participants  received either a once-daily  600 mg dose of EDP-323 for five days [hig","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/duWwzJl3g4gfLmJLgxAfsg--~B/aD03MzI7dz0yMTkwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/business-wire.com/ded82048504c55dff7f880137a591978","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/duWwzJl3g4gfLmJLgxAfsg--~B/aD03MzI7dz0yMTkwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/business-wire.com/ded82048504c55dff7f880137a591978"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/enanta-pharmaceuticals-announces-positive-topline-100000763.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["ENTA","BK4139","QD","BK4503","BK4563","BK4166"],"gpt_icon":0},{"id":"2469116614","title":"Kazia Therapeutics Announces Presentation of EVT801 Clinical Data at 15th Biennial Ovarian Cancer Research Symposium","url":"https://stock-news.laohu8.com/highlight/detail?id=2469116614","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2469116614?lang=en_us&edition=fundamental","pubTime":"2024-09-23 20:30","pubTimestamp":1727094600,"startTime":"0","endTime":"0","summary":"SYDNEY, Sept. 23, 2024 /PRNewswire/ -- Kazia Therapeutics Limited , an oncology-focused drug development company, is pleased to announce the presentation of data highlighting promising clinical activity of EVT801 in high grade serous  Ovarian Cancer at the 15th Biennial Ovarian Cancer Research Symposium, co-presented by American Association of Cancer Research  and the Rivkin Center for Ovarian Cancer Research on Saturday, September 21, 2024 in Seattle Washington.Dr. John Friend, CEO Kazia Therapeutics presented preliminary data from a Phase 1 first-in-human clinical trial evaluating the safety and tolerability of EVT801, a highly selective small molecule VEGFR3 inhibitor targeting tumour angiogenesis. The Phase 1 study met its primary objectives, with the maximal tolerated dose identified at 500mg twice a day . The Phase 1 study also identified the recommended Phase 2 dose starting at 400mg BID. It was observed that EVT801 was tolerated across all doses, with the majority of toxicities","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/7d1Pp00nd36xGLybjR7CaQ--~B/aD0xNTA7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/a0db042be43a53b84547568a8e78101c","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/7d1Pp00nd36xGLybjR7CaQ--~B/aD0xNTA7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/a0db042be43a53b84547568a8e78101c"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/kazia-therapeutics-announces-presentation-evt801-123000464.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/kazia-therapeutics-announces-presentation-evt801-123000464.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","QD","BK4166","BK4503","BK4563","KZIA","LENZ"],"gpt_icon":0},{"id":"2468482147","title":"Incyte Announces Promising New Data on Oncology Candidate at ESMO","url":"https://stock-news.laohu8.com/highlight/detail?id=2468482147","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2468482147?lang=en_us&edition=fundamental","pubTime":"2024-09-17 01:21","pubTimestamp":1726507260,"startTime":"0","endTime":"0","summary":"Incyte INCY announced new data from a phase I study on pipeline candidate INCB123667 in patients with advanced solid tumors.INCB123667 is a highly selective, potential first-in-class CDK2 inhibitor.The new data was presented during a mini-oral presentation at the European Society of Medical Oncology.The updated data highlight the potential of the candidate as a differentiated treatment option for cancers with increased cyclin E1 activity, amplification and/or overexpression in cells predictive of CDK2 dependency.Shares of Incyte have risen 3.1% year to date compared with the industry’s growth of 0.5%.Nine participants of the 37 evaluable participants with platinum-resistant ovarian cancer treated at three selected dose levels  in this portion of the trial experienced an overall response . Two of them achieved complete responses  and seven obtained partial responses .The highest OR rate of 31.3% was found in the 50mg BID cohort. Additionally, a disease control rate of 75.7% was achieved","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/sb.6qRd7FfGt7.wCjWz2vw--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/675c0ae70cb5036ad2ceb9062f13afc2","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/sb.6qRd7FfGt7.wCjWz2vw--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/675c0ae70cb5036ad2ceb9062f13afc2"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/incyte-announces-promising-data-oncology-172100704.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4007","FULC","MTD","KRYS","BK4017","BK4585","BK4166","BK4503","BK4550","BK4139","BK4532","BK4548","LU1721428933.USD","LU1093756168.USD","INCY","LU2413666426.HKD","BK4567","CR","BK4588","OR","BK4161","BK4563","LU2413666699.HKD","BK4121","SNDX","QD","LU0347712357.USD","BK4533","LU1093756325.SGD"],"gpt_icon":0},{"id":"2467607590","title":"Nuvalent Highlights Presentation of Clinical Data at ESMO 2024 for Parallel Lead Programs for ROS1 and ALK-positive NSCLC and Accelerated Development Timelines","url":"https://stock-news.laohu8.com/highlight/detail?id=2467607590","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2467607590?lang=en_us&edition=fundamental","pubTime":"2024-09-14 17:00","pubTimestamp":1726304400,"startTime":"0","endTime":"0","summary":"Updated Phase 1 dose-escalation data from ARROS-1 and ALKOVE-1 clinical trials continue to support potential best-in-class profiles for zidesamtinib and NVL-655. Rapid enrollment in Phase 2 portions of the ARROS-1 and ALKOVE-1 clinical trials; Pivotal data from both ROS1 and ALK programs now anticipated in 2025. Initiation of ALKAZAR Phase 3 randomized, controlled trial of NVL-655 for treatment-nave patients with advanced ALK-positive NSCLC anticipated in the first half of 2025. Company to host a conference call today at 8:30 a.m. ET/2:30 p.m. CEST. ALKAZAR Phase 3 randomized, controlled trial of NVL-655 for TKI-nave patients with advanced ALK-positive NSCLC: The Phase 3 ALKAZAR trial will be a global, randomized, controlled trial designed to evaluate NVL-655 versus the current standard of care for the treatment of patients with TKI-nave ALK-positive NSCLC. Patients will be randomized 1:1 to receive NVL-655 monotherapy or ALECENSA  monotherapy, reflecting input from collaborating physi","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/3pzNUKilN4Kx4KmjfFqBRA--~B/aD0xMTk7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/006d4b5652d5dd7204d997761f53cb52","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/3pzNUKilN4Kx4KmjfFqBRA--~B/aD0xMTk7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/006d4b5652d5dd7204d997761f53cb52"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/nuvalent-highlights-presentation-clinical-data-090000835.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/nuvalent-highlights-presentation-clinical-data-090000835.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2413666699.HKD","BK4135","LU1093756325.SGD","BK4139","BK4585","BK4166","BK4500","BK4195","BK4121","LU0347712357.USD","BK4503","BK4563","BK4097","NUVL","BK4211","MTD","LU1721428933.USD","LU2413666426.HKD","BK4548","LU1093756168.USD","QD","BK4588","BK4008","CNS","BK4567","PFS","ALK","BK4539","BK4533","OS"],"gpt_icon":0},{"id":"2467082645","title":"ESSA Pharma Presents Updated Phase 1/2 Masofaniten (EPI-7386) Clinical Data at the 2024 ESMO Congress","url":"https://stock-news.laohu8.com/highlight/detail?id=2467082645","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2467082645?lang=en_us&edition=fundamental","pubTime":"2024-09-14 05:19","pubTimestamp":1726262340,"startTime":"0","endTime":"0","summary":"Combination of masofaniten plus enzalutamide continues to be well tolerated with durable reductions in PSA in patients with mCRPC. Phase 2 dose expansion currently underway at the RP2CDs of masofaniten 600 mg BID in combination with enzalutamide 160 mg QD. Across all dosing cohorts, 88% of patients achieved PSA90, 69% of patients achieved PSA90 in less than 90 days, and 63% of patients achieved PSA <0.2ng/mL. After 15.2 months of follow up, median time to PSA progression and radiographic progression free survival have not yet been reached.Title:Phase 1/2 trial of oral EPI-7386  in combination with enzalutamide  compared with Enz alone in subjects with metastatic castration-resistant prostate cancer : Phase 1 results and Phase 2 designPresenting Author:Christos Kyriakopoulos, MD, University of Wisconsin-Madison Carbone Cancer CenterPresentation #:1641PDate and time: Sunday, September 15, 2024; 12:00-1:30 p.m. CEST/ 6:00-7:30 a.m. ET. Data summary: This Phase 1/2 multicenter, open-label ","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/ncyP05DE5y6K3EKDxJpMxQ--~B/aD0xNjt3PTE2O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/prnewswire.com/3adb42c2627903cc92d3e6129fdab790","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/ncyP05DE5y6K3EKDxJpMxQ--~B/aD0xNjt3PTE2O2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/prnewswire.com/3adb42c2627903cc92d3e6129fdab790"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/essa-pharma-presents-updated-phase-211900257.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/essa-pharma-presents-updated-phase-211900257.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4503","ESSA","LU2413666699.HKD","QD","LU1093756168.USD","LU2413666426.HKD","BK4211","BK4585","BK4548","BK4166","BK4563","LU1721428933.USD","LU1093756325.SGD","BK4195","BK4567","LU0347712357.USD","MTD","EPIX","BK4588","BK4121","BK4139","BK4533"],"gpt_icon":0}],"pageSize":16,"totalPage":5,"pageCount":4,"totalSize":71}]}}