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signal in AA is encouraging, the trial \"barely worked\" and overall data is significantly below expectations   ** Sees limited hope for applicability of the study for AA based on totality of data   ** Four of seven brokerages rate stock \"buy\" or higher, three \"hold\"; their median PT is $20   ** Including session's moves, stock d","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.rkd.refinitiv.com/api/News/News.svc/REST/News_1/RetrieveStoryML_1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QTTB"],"gpt_icon":0},{"id":"2491577331","title":"Q32 Bio Inc Shares Hit Record Low After Guggenheim Downgrades Stock, Last Down 21.2%","url":"https://stock-news.laohu8.com/highlight/detail?id=2491577331","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491577331?lang=en_us&edition=fundamental","pubTime":"2024-12-13 01:00","pubTimestamp":1734022859,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241212:nFWN3ND0OZ:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","QTTB"],"gpt_icon":0},{"id":"2491377703","title":"Here's Why Q32 Bio Stock Hit a New Record Low on Wednesday","url":"https://stock-news.laohu8.com/highlight/detail?id=2491377703","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2491377703?lang=en_us&edition=fundamental","pubTime":"2024-12-13 00:00","pubTimestamp":1734019200,"startTime":"0","endTime":"0","summary":"Shares of Q32 Bio QTTB lost nearly 77% yesterday after it reported mixed results from two separate phase IIa studies evaluating its investigational drug bempikibart one in atopic dermatitis  and the other in alopecia areata .While data from the AA study showed promising clinical activity for the drug, the study did not meet its primary endpoint in part B of the eczema study.Based on the above results, management has decided to proceed with developing the drug for AA, but will no longer pursue development in the eczema indication.Following the news, shares of Q32 Bio hit an all-time low of $5.80. The latest announcement did not impress investors, who raised concerns about the drug’s efficacy. Wall Street analysts were also not impressed with the results, one even calling it ‘messy.’。Year to date, Q32 Bio’s shares have lost 45.6% compared with the industry’s 8.7% decline.In the past 60 days, 2024 estimates for Castle Biosciences have improved from a loss of 58 cents per share to earnings","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/B7EfA6ERTo_QO90H15uyXw--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/9c1d11cd27737fac4805145de6e5eee0","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/B7EfA6ERTo_QO90H15uyXw--~B/aD00MDA7dz02MzU7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/zacks.com/9c1d11cd27737fac4805145de6e5eee0"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/heres-why-q32-bio-stock-160000430.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4196","SPRO","BK4139","AA","BK4585","BK4588","BK4153","CTMX","CSTL","QTTB"],"gpt_icon":0},{"id":"2490380148","title":"Q32 Bio Cut to Neutral From Buy by Guggenheim","url":"https://stock-news.laohu8.com/highlight/detail?id=2490380148","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490380148?lang=en_us&edition=fundamental","pubTime":"2024-12-12 23:24","pubTimestamp":1734017040,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/QTTB/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  December 12, 2024 10:24 ET (15:24 GMT)","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["QTTB"],"gpt_icon":0},{"id":"2490680067","title":"Q32 Bio Inc : Bmo Cuts Target Price to $22 From $64","url":"https://stock-news.laohu8.com/highlight/detail?id=2490680067","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490680067?lang=en_us&edition=fundamental","pubTime":"2024-12-12 20:46","pubTimestamp":1734007572,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241212:nFWN3ND16L:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","QTTB"],"gpt_icon":0},{"id":"2490800105","title":"Q32 Bio price target lowered to $20 from $80 at Oppenheimer","url":"https://stock-news.laohu8.com/highlight/detail?id=2490800105","media":"TipRanks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490800105?lang=en_us&edition=fundamental","pubTime":"2024-12-12 20:45","pubTimestamp":1734007529,"startTime":"0","endTime":"0","summary":"Oppenheimer lowered the firm’s price target on Q32 Bio  to $20 from $80 and keeps an Outperform rating on the shares. The firm notes Q32 Bio reported negative AD but positive AA results along with an update on clinical development plans for bempikibart. While Oppenheimer is clearly disappointed by bempi’s failure to advance in AD, it also thinks the AA opportunity remains underappreciated, with a potentially differentiated MoA in a highly underserved disease dominated by JAK inhibitors.Discover top-rated stocks from highly ranked analysts with Analyst Top Stocks!Easily identify outperforming stocks and invest smarter with Top Smart Score Stocks. Q32 Bio Announces Mixed Results in Clinical Trials. Q32 Bio downgraded to Market Perform from Outperform at Leerink. Q32 Bio downgraded to Outperform from Strong Buy at Raymond James. Q32 Bio downgraded to Equal Weight from Overweight at Wells Fargo","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/JAkd0u.p7aqm9cNkwT3ICg--~B/aD0xOTI7dz0xOTI7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/tipranks_452/c7cc0ee97ba22ee31ce2f6fcf51d1f91","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/JAkd0u.p7aqm9cNkwT3ICg--~B/aD0xOTI7dz0xOTI7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/tipranks_452/c7cc0ee97ba22ee31ce2f6fcf51d1f91"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/q32-bio-price-target-lowered-124529735.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/q32-bio-price-target-lowered-124529735.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["OPY","QTTB"],"gpt_icon":0},{"id":"2490180901","title":"Q32 Bio Inc : Guggenheim Cuts to Neutral","url":"https://stock-news.laohu8.com/highlight/detail?id=2490180901","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2490180901?lang=en_us&edition=fundamental","pubTime":"2024-12-12 19:32","pubTimestamp":1734003123,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20241212:nFWN3ND0UW:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4139","QTTB"],"gpt_icon":0}],"pageSize":16,"totalPage":5,"pageCount":2,"totalSize":67}]}}